Thiago Guedes Pinto, Thayza Aires Dias, Patricia Ramos Cury, Ana Claudia Muniz Renno, Glenda Nicioli da Silva, Daniel Araki Ribeiro
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Abstract
The present systematic review, through the analysis of several studies, focused on attempting to answer the following question: Is the micronucleus assay suitable for genetic biomonitoring of workers exposed to anesthetic gases? We conducted searches in PubMed, SCOPUS and Web of Science to identify eligible articles on December, 2023. After screening the manuscript, a total of 18 articles were included in the review. In the quality assessment, a total of 12 studies were rated as strong, 3 studies were rated as moderate and 3 were rated as weak. Taken as a whole, the results suggest that occupational exposure to different anesthetic agents may induce genome damage and that the micronucleus assay appears to be a reliable and suitable DNA damage biomarker for professionals chronically exposed to anesthetics.
期刊介绍：
International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.
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