Mechanical analysis of bone fracture treatment with hydrogel adhesives

IF 3.2 3区 材料科学 Q2 ENGINEERING, CHEMICAL International Journal of Adhesion and Adhesives Pub Date : 2024-10-29 DOI:10.1016/j.ijadhadh.2024.103873
Yufei Wu , Jun Liu , Hao Liu , Zhen Zhang , Peijian Chen , Xuhao Huang
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Abstract

As a new kind of material with outstanding biocompatibility and tunable mechanical properties, hydrogel can serve in significant applications, such as biological tissue repair, biomedical implantation, and so on. However, the lack of the mechanical analysis of bone fracture treatment with hydrogel adhesives hinders the development of clinical applications. In this paper, a three dimensional bonded butt model is established to predict the mechanical behavior of treated bones by using a bilinear cohesive zone model. The force-displacement curve, ultimate load, and consumed energy, as well as damage evolution affected by various geometric and material factors are analyzed. It is found that designing hydrogel adhesives of suitable thickness and weight ratio is helpful for improving the strength of bonded structures. The strength of boned structures decreases due to Mullins effect of the hydrogel adhesive. The results should be helpful for predicting mechanical behavior of bonded bone with hydrogel adhesives, and inspiring more works on the applications in clinical practice.
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使用水凝胶粘合剂处理骨折的力学分析
水凝胶作为一种新型材料,具有出色的生物相容性和可调机械特性,可在生物组织修复、生物医学植入等方面发挥重要作用。然而,由于缺乏对水凝胶粘合剂治疗骨折的力学分析,阻碍了临床应用的发展。本文建立了一个三维粘接对接模型,利用双线性内聚区模型预测处理后骨骼的力学行为。分析了受各种几何和材料因素影响的力-位移曲线、极限载荷、消耗能量以及损伤演变。研究发现,设计合适厚度和重量比的水凝胶粘合剂有助于提高粘合结构的强度。由于水凝胶粘合剂的 Mullins 效应,带骨结构的强度会降低。研究结果将有助于预测使用水凝胶粘合剂粘合骨的机械行为,并激励更多的临床应用研究。
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来源期刊
International Journal of Adhesion and Adhesives
International Journal of Adhesion and Adhesives 工程技术-材料科学:综合
CiteScore
6.90
自引率
8.80%
发文量
200
审稿时长
8.3 months
期刊介绍: The International Journal of Adhesion and Adhesives draws together the many aspects of the science and technology of adhesive materials, from fundamental research and development work to industrial applications. Subject areas covered include: interfacial interactions, surface chemistry, methods of testing, accumulation of test data on physical and mechanical properties, environmental effects, new adhesive materials, sealants, design of bonded joints, and manufacturing technology.
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