Metabolomics for the identification of biomarkers in endometriosis.

IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Archives of Gynecology and Obstetrics Pub Date : 2024-11-04 DOI:10.1007/s00404-024-07796-5
Swarnima Pandey
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Abstract

Background: Endometriosis affects the quality of life in women during their reproductive years, causing immense pain and can result in infertility. It is characterized by inflammation and the growth of the endometrium outside the uterine cavity. Metabolomics has the potential to resolve the major bottleneck of endometriosis which is delay in diagnosis due to the invasive diagnostic approach.In this review, the author has summarized the identified biomarkers of endometriosis from different bodily fluids. Metabolomics promises a non-invasive diagnostic approach for endometriosis that could aid in earlier diagnosis and prognosis.

Methods: Patients with endometriosis keywords were searched in correspondence with the assigned keywords, including metabolomics from PubMed, from its inception to Dec 2023. The relevant studies from this search were extracted and included in the study.

Results: This article provides information regarding metabolomics studies in endometrisis.

Conclusions: We demonstrated that metabolomics is about to change the world of endometriosis by analyzing and detecting the diagnosis, prognosis, mortality and treatment response biomarkers.

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用于鉴定子宫内膜异位症生物标志物的代谢组学。
背景:子宫内膜异位症影响育龄妇女的生活质量,给她们带来巨大的痛苦,并可能导致不孕。子宫内膜异位症的特点是炎症和子宫内膜在子宫腔外生长。在这篇综述中,作者总结了从不同体液中发现的子宫内膜异位症生物标志物。代谢组学有望成为子宫内膜异位症的非侵入性诊断方法,有助于早期诊断和预后:从 PubMed 开始到 2023 年 12 月,对子宫内膜异位症患者的关键词进行了检索,包括代谢组学。结果:本文提供了有关代谢组学的信息:本文提供了有关子宫内膜异位症代谢组学研究的信息:我们证明,代谢组学通过分析和检测诊断、预后、死亡率和治疗反应生物标志物,即将改变子宫内膜异位症的世界。
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来源期刊
CiteScore
4.70
自引率
15.40%
发文量
493
审稿时长
1 months
期刊介绍: Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report". The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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