Atractylodis macrocephalae rhizoma tianma soup mixed with peach kernel safflower fried in the treatment of acute cerebral infarction: A randomized controlled trial.

IF 0.7 4区 医学 Q4 PHARMACOLOGY & PHARMACY Pakistan journal of pharmaceutical sciences Pub Date : 2024-09-01
Yaowen Zhang, Yongtao Wei, Yingying Chen, Mingyi Zhao
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Abstract

We studied the effectiveness of Atractylodis Macrocephalae Rhizoma Tianma soup mixed with peach kernel safflower Fried in treating acute cerebral infarction. 96 patients were divided into two groups and received routine treatment as per hospital guidelines. 48 patients were given the herbal mixture while the rest were not. A comparison of inflammatory factors, coagulation, liver and kidney function showed significant differences between the two groups on day 14. The observation group had higher APTT, PT, TT values and ALP levels, but lower BUN levels compared to the control group. The observation group had significantly higher ALP levels and GGT levels on day 14 compared to the control group, while Cr and BUN levels were lower. This difference was statistically significant (P<0.05). The peach kernel safflower fried and Attractylodis Macrocephalae Rhizoma Tianma soup combination reduces inflammation in acute cerebral infarction patients, improving clinical symptoms without any reported adverse reactions.

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白术天麻汤合桃仁红花炒治疗急性脑梗塞:随机对照试验。
我们研究了白术天麻汤混合桃仁红花油治疗急性脑梗塞的疗效。96 名患者被分为两组,按照医院指南接受常规治疗。48 名患者服用了中药混合物,其余患者未服用。对炎症因子、凝血功能、肝肾功能的比较显示,两组患者在第 14 天时存在显著差异。与对照组相比,观察组的 APTT、PT、TT 值和 ALP 水平较高,但 BUN 水平较低。与对照组相比,观察组在第 14 天的 ALP 水平和 GGT 水平明显较高,而 Cr 和 BUN 水平较低。这一差异具有统计学意义(P
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来源期刊
CiteScore
1.40
自引率
12.50%
发文量
211
审稿时长
4.5 months
期刊介绍: Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013. PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.
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