{"title":"Effects of freezing of gait on vertical ground reaction force in Parkinson's disease","authors":"","doi":"10.1016/j.humov.2024.103301","DOIUrl":null,"url":null,"abstract":"<div><div>Vertical ground reaction force (vGRF) is a main kinetic gait analysis explaining body weight loading patterns. The study primarily aimed to understand effects of Freezing of gait (FoG) on vGRF in Parkinson's disease (PD). A secondary analysis for a walking dataset including biomechanical analyses for 26 PD participants (13 with FoG) was performed. Considering the normal pattern of vGRF curve, peaks during early stance (F1) and late stance (F3), and slope in- during mid-stance (F2) were used to represent the change in kinetic forces. vGRF parameters were compared between FoG and non-FoG participants, and at off- and on-medication. FoG participants showed higher vGRFs during mid-stance F2 magnitude (<em>p</em> = 0.003), and weaker vertical propulsion; F3 magnitude (<em>p</em> < 0.001). This coincided with delayed weight acceptance; F1 timing (<em>p</em> = 0.019), and midstance peaks; F2 timing (<em>p</em> = 0.004). At off-medications, the F2 magnitude was significantly higher (<em>p</em> = 0.006), F3 magnitude lower (<em>p</em> = 0.001), and F1 time slower (<em>p</em> = 0.034) in FoG. At on-medication, F3 magnitude was still significantly lower (<em>p</em> = 0.017), and F2 time was slower (<em>p</em> = 0.037) in FoG. This study reveals that FoG significantly affects vGRF, particularly F3 magnitude during the push-off phase. Analyzing vGRF is crucial for understanding and managing FoG, allowing for more targeted interventions to improve FoG outcomes.</div></div>","PeriodicalId":55046,"journal":{"name":"Human Movement Science","volume":null,"pages":null},"PeriodicalIF":1.6000,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Movement Science","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S016794572400126X","RegionNum":3,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Vertical ground reaction force (vGRF) is a main kinetic gait analysis explaining body weight loading patterns. The study primarily aimed to understand effects of Freezing of gait (FoG) on vGRF in Parkinson's disease (PD). A secondary analysis for a walking dataset including biomechanical analyses for 26 PD participants (13 with FoG) was performed. Considering the normal pattern of vGRF curve, peaks during early stance (F1) and late stance (F3), and slope in- during mid-stance (F2) were used to represent the change in kinetic forces. vGRF parameters were compared between FoG and non-FoG participants, and at off- and on-medication. FoG participants showed higher vGRFs during mid-stance F2 magnitude (p = 0.003), and weaker vertical propulsion; F3 magnitude (p < 0.001). This coincided with delayed weight acceptance; F1 timing (p = 0.019), and midstance peaks; F2 timing (p = 0.004). At off-medications, the F2 magnitude was significantly higher (p = 0.006), F3 magnitude lower (p = 0.001), and F1 time slower (p = 0.034) in FoG. At on-medication, F3 magnitude was still significantly lower (p = 0.017), and F2 time was slower (p = 0.037) in FoG. This study reveals that FoG significantly affects vGRF, particularly F3 magnitude during the push-off phase. Analyzing vGRF is crucial for understanding and managing FoG, allowing for more targeted interventions to improve FoG outcomes.
期刊介绍:
Human Movement Science provides a medium for publishing disciplinary and multidisciplinary studies on human movement. It brings together psychological, biomechanical and neurophysiological research on the control, organization and learning of human movement, including the perceptual support of movement. The overarching goal of the journal is to publish articles that help advance theoretical understanding of the control and organization of human movement, as well as changes therein as a function of development, learning and rehabilitation. The nature of the research reported may vary from fundamental theoretical or empirical studies to more applied studies in the fields of, for example, sport, dance and rehabilitation with the proviso that all studies have a distinct theoretical bearing. Also, reviews and meta-studies advancing the understanding of human movement are welcome.
These aims and scope imply that purely descriptive studies are not acceptable, while methodological articles are only acceptable if the methodology in question opens up new vistas in understanding the control and organization of human movement. The same holds for articles on exercise physiology, which in general are not supported, unless they speak to the control and organization of human movement. In general, it is required that the theoretical message of articles published in Human Movement Science is, to a certain extent, innovative and not dismissible as just "more of the same."