Luca Nicchio, Lorenzo Di Terlizzi, luc Neuville, Maurizio Fagnoni, Stefano Protti, Géraldine Masson
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引用次数: 0
Abstract
We present a novel and highly efficient method for synthesizing polyfunctionalized 1,2,4-triazoles. This approach leverages visible light and arylazo sulfones in combination with N-vinyl amides, in the environmentally friendly solvent ethyl acetate. Remarkably, the reaction proceeds without the need for (photo)catalysts, ensuring near-perfect atom economy and producing only water as a by-product. This method exhibits excellent functional group tolerance and can be scaled for both batch and continuous-flow processes.
期刊介绍：
Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry.
The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.
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