Intraductal papillary mucinous neoplasm: Overview of management.

IF 1.6 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Australian Journal of General Practice Pub Date : 2024-11-01 DOI:10.31128/AJGP-05-23-6822
June Oo, Lisa Brown, Benjamin PT Loveday
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Abstract

Background: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is increasingly being diagnosed incidentally on imaging. It has malignant potential, making it vital to establish the correct diagnosis, assess its malignant risk and follow a management strategy to prevent development of invasive carcinoma of the pancreas.

Objective: This review focuses on the epidemiology, natural history, risk factors, diagnosis and management of IPMN of the pancreas, and will provide practical points for general practitioners.

Discussion: IPMN of the pancreas can transform into invasive pancreatic carcinoma at a low rate of approximately 2%/year. Upon diagnosis of IPMN, it is risk stratified based on the presence of worrisome or high-risk stigmata, which guides further management. Management needs to be individualised based on IPMN and patient factors due to limitations with the current diagnostic tools.

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导管内乳头状粘液瘤:治疗概述。
背景:越来越多的胰腺导管内乳头状粘液瘤(IPMN)是通过影像学检查偶然诊断出来的。IPMN 有恶变的可能,因此必须确定正确的诊断、评估其恶变风险并采取相应的管理策略,以防止发展为胰腺浸润性癌:本综述侧重于胰腺 IPMN 的流行病学、自然史、风险因素、诊断和管理,并将为全科医生提供实用要点:讨论:胰腺 IPMN 可转化为浸润性胰腺癌,转化率较低,约为 2%/年。在确诊 IPMN 后,应根据是否存在令人担忧或高风险的标志对其进行风险分层,从而指导进一步的治疗。由于现有诊断工具的局限性,需要根据 IPMN 和患者因素进行个性化管理。
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来源期刊
Australian Journal of General Practice
Australian Journal of General Practice Medicine-Family Practice
CiteScore
2.80
自引率
4.50%
发文量
284
期刊介绍: The Australian Journal of General Practice (AJGP) aims to provide relevant, evidence-based, clearly articulated information to Australian general practitioners (GPs) to assist them in providing the highest quality patient care, applicable to the varied geographic and social contexts in which GPs work and to all GP roles as clinician, researcher, educator, practice team member and opinion leader. All articles are subject to peer review before they are accepted for publication.
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