Latest trends in biosensors powered by nucleic acid isothermal amplification for the diagnosis of joint infections: From sampling to identification towards the point-of-care

IF 11.8 1区 化学 Q1 CHEMISTRY, ANALYTICAL Trends in Analytical Chemistry Pub Date : 2024-11-03 DOI:10.1016/j.trac.2024.118036
{"title":"Latest trends in biosensors powered by nucleic acid isothermal amplification for the diagnosis of joint infections: From sampling to identification towards the point-of-care","authors":"","doi":"10.1016/j.trac.2024.118036","DOIUrl":null,"url":null,"abstract":"<div><div>As the number of joint arthroplasties continues to increase, joint infections have emerged as a significant and devastating complication associated with total joint arthroplasty. The formation and persistence of bacterial biofilms create a formidable barrier against both the host immune system and antibiotics, contributing to the pathogenesis of joint infections, antibiotic resistance, and treatment failures. This review examines the latest trends on biosensors powered by isothermal nucleic acid amplification technologies designed to manage joint infections, highlighting their advantages and disadvantages, with a particular attention on their integration into point-of-care testing. In detail, a special focus on such innovative approaches for rapid and specific identification of pathogenic nucleic acids will cover the entire process from sampling to extraction, amplification, and detection methods.</div></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624005193","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

Abstract

As the number of joint arthroplasties continues to increase, joint infections have emerged as a significant and devastating complication associated with total joint arthroplasty. The formation and persistence of bacterial biofilms create a formidable barrier against both the host immune system and antibiotics, contributing to the pathogenesis of joint infections, antibiotic resistance, and treatment failures. This review examines the latest trends on biosensors powered by isothermal nucleic acid amplification technologies designed to manage joint infections, highlighting their advantages and disadvantages, with a particular attention on their integration into point-of-care testing. In detail, a special focus on such innovative approaches for rapid and specific identification of pathogenic nucleic acids will cover the entire process from sampling to extraction, amplification, and detection methods.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
利用核酸等温扩增技术诊断关节感染的生物传感器的最新发展趋势:从采样到鉴定,迈向护理点
随着关节置换数量的不断增加,关节感染已成为与全关节置换术相关的一种严重且具有破坏性的并发症。细菌生物膜的形成和持续存在对宿主免疫系统和抗生素形成了一道强大的屏障,导致了关节感染的发病机制、抗生素耐药性和治疗失败。这篇综述探讨了利用等温核酸扩增技术设计的生物传感器的最新发展趋势,旨在管理关节感染,重点介绍其优缺点,尤其关注其与护理点检测的整合。在细节方面,将特别关注此类快速、特异性鉴定病原体核酸的创新方法,涵盖从取样到提取、扩增和检测方法的整个过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Trends in Analytical Chemistry
Trends in Analytical Chemistry 化学-分析化学
CiteScore
20.00
自引率
4.60%
发文量
257
审稿时长
3.4 months
期刊介绍: TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.
期刊最新文献
Latest trends in biosensors powered by nucleic acid isothermal amplification for the diagnosis of joint infections: From sampling to identification towards the point-of-care Recommendations, trends and analytical strategies applied for biological samples collection (sampling) and storage in forensic toxicology of volatile poisons (inorganic and organic) Multimodal probes for the detection of bone cancer-related disease in biological systems: Recent advances and future prospects Analytical methods for protein kinase and inhibitor screening including kinetic evaluation Virgin olive oil authentication using mass spectrometry-based approaches: A review
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1