{"title":"Exploiting Spinach-Derived Extracellular Vesicles for Anti-Obesity Therapy Through Lipid Accumulation Inhibition (Adv. Therap. 11/2024)","authors":"Jeong Hyun Lee, Su Jin Kang, Won Jong Rhee","doi":"10.1002/adtp.202470024","DOIUrl":null,"url":null,"abstract":"<p>The spinach-derived extracellular vesicles (Spinex) isolated from spinach efficiently suppressed lipid accumulation during adipocyte differentiation. The anti-obesity properties of Spinex are also demonstrated in a high-fat diet-induced mouse model. The research highlights Spinex as a promising natural biomaterial for combating obesity. More details can be found in article 2400150 by Won Jong Rhee and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7284,"journal":{"name":"Advanced Therapeutics","volume":"7 11","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adtp.202470024","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Therapeutics","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adtp.202470024","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
The spinach-derived extracellular vesicles (Spinex) isolated from spinach efficiently suppressed lipid accumulation during adipocyte differentiation. The anti-obesity properties of Spinex are also demonstrated in a high-fat diet-induced mouse model. The research highlights Spinex as a promising natural biomaterial for combating obesity. More details can be found in article 2400150 by Won Jong Rhee and co-workers.
从菠菜中分离出的菠菜源细胞外囊泡(Spinex)能有效抑制脂肪细胞分化过程中的脂质积累。Spinex 的抗肥胖特性还在高脂饮食诱导的小鼠模型中得到了证实。这项研究表明,Spinex 是一种很有前景的抗肥胖天然生物材料。更多详情,请参阅 Won Jong Rhee 及其合作者撰写的文章 2400150。