Clinical and Radiographic Features of Peri-Implant Medication-Related Osteonecrosis of the Jaw: A Retrospective Study

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Implant Dentistry and Related Research Pub Date : 2024-11-06 DOI:10.1111/cid.13412

Hyeon-Gyu Jo, Wonse Park, In-Ho Cha, Young-Soo Jung, Da Yun Lee, Jun-Young Kim

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Abstract

Introduction

This study aimed to analyze the factors affecting the occurrence of peri-implant medication-related osteonecrosis of the jaw (PI-MRONJ) in patients using anti-resorptive drugs (ARDs) on different implant position, inclinations, and types of prosthesis.

Methods

The data of 75 patients with bone necrosis that progressed around the implant between 2018 and 2022 were retrospectively examined to identify the factors influencing PI-MRONJ. Data, including patient demographics (age, sex, smoking status, concomitant disease, time of ARD therapy, dose of ARDs, and parafunctional habits) and implant-specific information (type of prosthesis, angle of insertion), were extracted from medical and dental records.

Results

Tilted implants with an angle ≥ 5.1° relative to the occlusal plane of the prosthesis had a stronger association with PI-MRONJ in comparison to non-tilted implants (inclination was < 5°). Additionally, the boundary of the area of osteonecrosis around the fixture was larger for the splinted implant-supported crowns than for the single implant supported crowns).

Conclusion

In patients taking anti-resorptive medications the inclination of the implant was associated with the occurrence of PI-MRONJ. Further studies are required to confirm the clinical findings.

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植入前药物相关性颌骨骨坏死的临床和放射学特征：一项回顾性研究

导言：该研究旨在分析在不同种植体位置、倾斜度和修复体类型上使用抗吸收药物（ARDs）的患者发生种植体周围药物相关性颌骨坏死（PI-MRONJ）的影响因素：回顾性研究了2018年至2022年间75例种植体周围骨坏死进展患者的数据，以确定影响PI-MRONJ的因素。数据包括患者人口统计学特征（年龄、性别、吸烟状况、伴随疾病、ARD治疗时间、ARD剂量和副功能习惯）和种植体特定信息（修复体类型、插入角度），均从医疗和牙科记录中提取：结果：与非倾斜种植体相比，相对于修复体咬合面角度≥5.1°的倾斜种植体与PI-MRONJ的关系更为密切（倾斜度为5.1°）：在服用抗骨质吸收药物的患者中，种植体的倾斜度与 PI-MRONJ 的发生有关。需要进一步的研究来证实临床发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Implant Dentistry and Related Research 医学-牙科与口腔外科

CiteScore

6.00

自引率

13.90%

发文量

103

审稿时长

4-8 weeks

期刊介绍： The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.