Wilawan Chaiyaporn, Teerawut Tangsathian, Kakanang Supanimitkul, Navawan Sophon, Tharntip Suwanwichit, Attawood Lertpimonchai, George Pelekos, Sirikarn P. Arunyanak, Kajorn Kungsadalpipob
Objective
To identify the site-related, implant characteristic-related, prosthetic, and patient-related factors associated with marginal bone level around dental implant-supported fixed prostheses.
Materials and Methods
This cross-sectional study analyzed clinical and radiographic data obtained during maintenance visits. The interproximal radiographic bone levels were selected at the site showing the greatest bone loss. The implants were classified as having a bone level ≥ 2 mm (BL group) or < 2 mm (NBL group). Multivariate multilevel logistic regression was used to assess the association between multiple factors and bone level ≥ 2 mm.
Results
A total of 196 subjects with 404 implants were included, with a mean follow-up period of 5.21 years. Implementing multifactorial analysis, the results demonstrated that probing depth ≥ 6 mm (odds ratios [OR] 5.39; 95% confidence intervals [CI] 1.21–24.06; p = 0.027), absence of keratinized mucosa (OR 3.54; 95% CI 1.11–11.28; p = 0.033), presence of an implant abutment microgap (OR 2.82; 95% CI 1.12–7.12; p = 0.028), transmucosal height < 2 mm (OR 4.79; 95% CI 1.85–12.41; p = 0.001), and a history of periodontitis (OR 2.80; 95% CI 1.08–7.24; p = 0.034) exhibited a significantly higher risk of marginal bone level ≥ 2 mm.
Conclusion
Marginal bone level around implant-supported prostheses was influenced by the interplay of multiple factors consisting of deep probing depth, absence of keratinized mucosa, inadequate transmucosal height, microgap configuration, and history of periodontitis. These findings emphasized the need for comprehensive peri-implant assessment, which included monitoring probing depths and soft tissue quality. Additionally, it was crucial to ensure that prostheses were well-designed and had the appropriate transmucosal height. Patients with a history of periodontitis were advised to follow a strict maintenance program. Further prospective studies are needed to confirm the causality for ongoing investigation into the specific aspects and mechanisms involved.
目的：探讨与种植体支撑固定修复体周围骨缘水平相关的部位、种植体特征、假体和患者相关因素。材料和方法：本横断面研究分析了在维持访问期间获得的临床和放射学数据。在显示骨质流失最严重的部位选择近端间x线骨水平。结果：共纳入196例受试者，植入物404个，平均随访时间5.21年。通过多因素分析，结果显示：探测深度≥6 mm（优势比[OR] 5.39； 95%可信区间[CI] 1.21-24.06; p = 0.027），没有角化粘膜（优势比[OR] 3.54； 95%可信区间[CI] 1.11-11.28; p = 0.033），存在种植基台微间隙(优势比[OR] 2.82； 95%可信区间[CI] 1.12-7.12；结论：种植体修复体周围边缘骨水平受探探深度深、无角化黏膜、黏膜高度不足、微间隙结构和牙周炎史等多种因素的相互作用影响。这些发现强调需要进行全面的种植体周围评估，包括监测探测深度和软组织质量。此外，确保假体设计良好并具有适当的粘膜高度也是至关重要的。有牙周炎病史的患者被建议遵循严格的保养计划。需要进一步的前瞻性研究来确认因果关系，以便对所涉及的具体方面和机制进行持续的调查。
{"title":"Marginal Bone Level Changes in Implant-Supported Fixed Prostheses in a Retrospective Study: A Multifactorial Analysis","authors":"Wilawan Chaiyaporn, Teerawut Tangsathian, Kakanang Supanimitkul, Navawan Sophon, Tharntip Suwanwichit, Attawood Lertpimonchai, George Pelekos, Sirikarn P. Arunyanak, Kajorn Kungsadalpipob","doi":"10.1111/cid.70115","DOIUrl":"10.1111/cid.70115","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To identify the site-related, implant characteristic-related, prosthetic, and patient-related factors associated with marginal bone level around dental implant-supported fixed prostheses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>This cross-sectional study analyzed clinical and radiographic data obtained during maintenance visits. The interproximal radiographic bone levels were selected at the site showing the greatest bone loss. The implants were classified as having a bone level ≥ 2 mm (BL group) or < 2 mm (NBL group). Multivariate multilevel logistic regression was used to assess the association between multiple factors and bone level ≥ 2 mm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 196 subjects with 404 implants were included, with a mean follow-up period of 5.21 years. Implementing multifactorial analysis, the results demonstrated that probing depth ≥ 6 mm (odds ratios [OR] 5.39; 95% confidence intervals [CI] 1.21–24.06; <i>p</i> = 0.027), absence of keratinized mucosa (OR 3.54; 95% CI 1.11–11.28; <i>p</i> = 0.033), presence of an implant abutment microgap (OR 2.82; 95% CI 1.12–7.12; <i>p</i> = 0.028), transmucosal height < 2 mm (OR 4.79; 95% CI 1.85–12.41; <i>p</i> = 0.001), and a history of periodontitis (OR 2.80; 95% CI 1.08–7.24; <i>p</i> = 0.034) exhibited a significantly higher risk of marginal bone level ≥ 2 mm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Marginal bone level around implant-supported prostheses was influenced by the interplay of multiple factors consisting of deep probing depth, absence of keratinized mucosa, inadequate transmucosal height, microgap configuration, and history of periodontitis. These findings emphasized the need for comprehensive peri-implant assessment, which included monitoring probing depths and soft tissue quality. Additionally, it was crucial to ensure that prostheses were well-designed and had the appropriate transmucosal height. Patients with a history of periodontitis were advised to follow a strict maintenance program. Further prospective studies are needed to confirm the causality for ongoing investigation into the specific aspects and mechanisms involved.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Moreira Cunha, Amanda Paino Santana, Mariana Martins Guerreiro, Akhilanand Chaurasia, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila
<p>There is no doubt that peri-implantitis is an inflammatory condition affecting the tissues surrounding dental implants, driven by a complex interplay between microbial dysbiosis and the host immune response [<span>1</span>]. Subclinical interactions between the dysbiotic biofilm and the host immune system are initiated largely by components of anaerobic Gram-negative bacteria, most notably lipopolysaccharide (LPS), which predominates at diseased peri-implant sites. LPS engages toll-like receptor 4 (TLR4) on epithelial and immune cells, activating transcriptional pathways that upregulate proinflammatory mediators and establish a permissive environment for leukocyte recruitment [<span>2</span>]. Neutrophils, macrophages, and dendritic cells are rapidly mobilized and amplify tissue destruction through the release of cytokines and extracellular matrix-degrading enzymes. Among these innate immune cells, macrophages play a particularly central role in peri-implant disease pathogenesis, exhibiting a pronounced shift toward an M1-dominant phenotype [<span>3, 4</span>]. Interestingly, macrophage polarization has also been implicated as a key pathogenic mechanism across a broad spectrum of chronic inflammatory diseases, including cancer, diabetes, atherosclerosis, and periodontitis [<span>5, 6</span>] supporting the notion that peri-implantitis may share pathogenic pathways with, and potentially associate with, other local and systemic inflammatory conditions. M1-polarized macrophages produce RANKL, reactive oxygen species, and matrix metalloproteinases, thereby promoting osteoclastogenesis and accelerating bone resorption. Neutrophils further contribute through membrane-bound RANKL expression and heightened sensitivity to microbial cues. As disease progresses, adaptive immunity becomes similarly dysregulated, with helper T-cells (CD4<sup>+</sup> T)-cell subsets, including Th1, Th2, Th17 cells, and regulatory T cells (Tregs), sustaining chronic inflammation and driving interleukin (IL-)17-mediated neutrophil recruitment and osteoclast activation. Tregs, characterized by expression of transcription factor forkhead box p3 (FOXP3), cluster of differentiation (CD)25, and the IL-2 receptor, are markedly elevated in peri-implantitis lesions and are typically associated with the production of IL-10, tgf beta growth factor (TGF)-β1, and IL-35. While IL-10 and TGF-β1 function as baseline homeostatic anti-inflammatory mediators, IL-35 is induced under intense inflammatory pressure. The observed imbalance with elevated FOXP3 and IL-35 coupled with reduced TGF-β1 suggests a dysfunctional or unstable Treg phenotype unable to effectively restrain inflammation, thereby contributing to the progressive soft- and hard-tissue destruction characteristic of peri-implantitis [<span>7</span>].</p><p>In simple terms, a dysbiotic biofilm, an imbalanced and pathogenic microbial community adhered to the implant surface, acts as the primary trigger, initiating an inflammatory casc
{"title":"Reconceptualizing Peri-Implantitis: Dual-Factor Inflammation and Its Role in Advancing Biomaterial Coatings","authors":"Daniela Moreira Cunha, Amanda Paino Santana, Mariana Martins Guerreiro, Akhilanand Chaurasia, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila","doi":"10.1111/cid.70108","DOIUrl":"10.1111/cid.70108","url":null,"abstract":"<p>There is no doubt that peri-implantitis is an inflammatory condition affecting the tissues surrounding dental implants, driven by a complex interplay between microbial dysbiosis and the host immune response [<span>1</span>]. Subclinical interactions between the dysbiotic biofilm and the host immune system are initiated largely by components of anaerobic Gram-negative bacteria, most notably lipopolysaccharide (LPS), which predominates at diseased peri-implant sites. LPS engages toll-like receptor 4 (TLR4) on epithelial and immune cells, activating transcriptional pathways that upregulate proinflammatory mediators and establish a permissive environment for leukocyte recruitment [<span>2</span>]. Neutrophils, macrophages, and dendritic cells are rapidly mobilized and amplify tissue destruction through the release of cytokines and extracellular matrix-degrading enzymes. Among these innate immune cells, macrophages play a particularly central role in peri-implant disease pathogenesis, exhibiting a pronounced shift toward an M1-dominant phenotype [<span>3, 4</span>]. Interestingly, macrophage polarization has also been implicated as a key pathogenic mechanism across a broad spectrum of chronic inflammatory diseases, including cancer, diabetes, atherosclerosis, and periodontitis [<span>5, 6</span>] supporting the notion that peri-implantitis may share pathogenic pathways with, and potentially associate with, other local and systemic inflammatory conditions. M1-polarized macrophages produce RANKL, reactive oxygen species, and matrix metalloproteinases, thereby promoting osteoclastogenesis and accelerating bone resorption. Neutrophils further contribute through membrane-bound RANKL expression and heightened sensitivity to microbial cues. As disease progresses, adaptive immunity becomes similarly dysregulated, with helper T-cells (CD4<sup>+</sup> T)-cell subsets, including Th1, Th2, Th17 cells, and regulatory T cells (Tregs), sustaining chronic inflammation and driving interleukin (IL-)17-mediated neutrophil recruitment and osteoclast activation. Tregs, characterized by expression of transcription factor forkhead box p3 (FOXP3), cluster of differentiation (CD)25, and the IL-2 receptor, are markedly elevated in peri-implantitis lesions and are typically associated with the production of IL-10, tgf beta growth factor (TGF)-β1, and IL-35. While IL-10 and TGF-β1 function as baseline homeostatic anti-inflammatory mediators, IL-35 is induced under intense inflammatory pressure. The observed imbalance with elevated FOXP3 and IL-35 coupled with reduced TGF-β1 suggests a dysfunctional or unstable Treg phenotype unable to effectively restrain inflammation, thereby contributing to the progressive soft- and hard-tissue destruction characteristic of peri-implantitis [<span>7</span>].</p><p>In simple terms, a dysbiotic biofilm, an imbalanced and pathogenic microbial community adhered to the implant surface, acts as the primary trigger, initiating an inflammatory casc","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Zingari, Francesco Gallo, Riccardo Finamore, Selene Barone, Amerigo Giudice
Aim
This 3D analysis assessed the accuracy of zygomatic implant (ZI) placement using a static surgical guide in correlation with ZAGA classification and the rehabilitation type.
Methods
Pre-surgical CT scans were used to create a virtual surgical plane, exported as .stl files, and to define the ZAGA classification of each implant. A CT scan was taken 6 months post-surgery, and segmentation of the zygomatic implants was performed. The 3D analysis on 3DSlicer software compared planned and placed zygomatic implants, measuring linear and angular displacements at the apex and base of each model. Displacements were correlated with the ZAGA classification and the type of rehabilitation (if quad, twin, or mono zygomatic implant).
Results
The study included 45 patients and 150 zygomatic implants, all placed using bone-supported surgical guides with no bone modifications. The implant survival rate was 100% at 6 months. Most patients received quad rehabilitation with 4 implants, and there was strong overlap between planned and placed implants. The mean surface displacement was 0.43 mm on the right and 0.45 mm on the left. The angular deviation between the planned and placed implant orientations was lower than 1° for both the anterior and posterior implants. According to ZAGA classification, surface displacement increased from class 0 to 4. No significant differences were found among the type of rehabilitation (p > 0.289).
Conclusion
The study highlights the accuracy of fully guided surgery for zygomatic implant placement, recommending its consideration in clinical decision-making. It also shows greater accuracy in lower ZAGA classes and no significant difference across rehabilitation types.
{"title":"Influence of ZAGA Classification on the Accuracy of 150 Digitally Planned Zygomatic Implants Placement","authors":"Francesco Zingari, Francesco Gallo, Riccardo Finamore, Selene Barone, Amerigo Giudice","doi":"10.1111/cid.70117","DOIUrl":"10.1111/cid.70117","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This 3D analysis assessed the accuracy of zygomatic implant (ZI) placement using a static surgical guide in correlation with ZAGA classification and the rehabilitation type.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Pre-surgical CT scans were used to create a virtual surgical plane, exported as .stl files, and to define the ZAGA classification of each implant. A CT scan was taken 6 months post-surgery, and segmentation of the zygomatic implants was performed. The 3D analysis on 3DSlicer software compared planned and placed zygomatic implants, measuring linear and angular displacements at the apex and base of each model. Displacements were correlated with the ZAGA classification and the type of rehabilitation (if quad, twin, or mono zygomatic implant).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 45 patients and 150 zygomatic implants, all placed using bone-supported surgical guides with no bone modifications. The implant survival rate was 100% at 6 months. Most patients received quad rehabilitation with 4 implants, and there was strong overlap between planned and placed implants. The mean surface displacement was 0.43 mm on the right and 0.45 mm on the left. The angular deviation between the planned and placed implant orientations was lower than 1° for both the anterior and posterior implants. According to ZAGA classification, surface displacement increased from class 0 to 4. No significant differences were found among the type of rehabilitation (<i>p</i> > 0.289).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The study highlights the accuracy of fully guided surgery for zygomatic implant placement, recommending its consideration in clinical decision-making. It also shows greater accuracy in lower ZAGA classes and no significant difference across rehabilitation types.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damla Eda Yapıcı Gulbey, Abdussamet Batur, Seyit Ali Kayis, Guliz Nigar Guncu, Sema S. Hakki
Introduction
Perforation is the most common complication of sinus floor elevation (SFE) surgery, and is closely associated with the thickness of the maxillary sinus membrane. This study aimed to evaluate the relationship between maxillary sinus membrane thickness and anatomical variations in the osteomeatal complex (OMC).
Methods
Cone beam computed tomography scans were retrospectively analyzed, encompassing 1957 sinuses. Mucosal thickness (MT) and mucosal appearance (MA) were classified as normal, flat thickening, polypoid thickening, or ostium obstruction. Ostium width (OW), infundibulum length (IL), and ethmoidal bulla diameter (EBD) were measured. The presence of Haller cells (HC), concha bullosa (CB), and superior attachment of the uncinate process (UPSA) was recorded. Kruskal–Wallis, Mann–Whitney U, Chi-square, and GEE models were used.
Results
Mucosal thickening was observed in 54% of the sinuses, with flat thickening (23.5%) being the most prevalent pattern. A significant association was found between ostium obstruction and MT greater than 10 mm. MT, IL, OW, and EBD values were significantly higher in men than in women. Significant correlations were also identified between MT and IL, OW, EBD, and HC. No significant relationship was found between CB and MT. However, UPSA types 3, 4, and 6 were significantly associated with polypoid thickening and ostium obstruction.
Conclusion
The findings demonstrate that anatomical variations in the OMC influence maxillary sinus membrane thickness. A comprehensive evaluation of these variations should be performed before planning for SFE procedures. Dentists should be proficient in identifying and assessing the osteomeatal region during routine radiographic examinations to prevent potential complications.
{"title":"Association Between Osteomeatal Complex Variations and Maxillary Sinus Membrane Thickness: A CBCT Study","authors":"Damla Eda Yapıcı Gulbey, Abdussamet Batur, Seyit Ali Kayis, Guliz Nigar Guncu, Sema S. Hakki","doi":"10.1111/cid.70121","DOIUrl":"10.1111/cid.70121","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Perforation is the most common complication of sinus floor elevation (SFE) surgery, and is closely associated with the thickness of the maxillary sinus membrane. This study aimed to evaluate the relationship between maxillary sinus membrane thickness and anatomical variations in the osteomeatal complex (OMC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Cone beam computed tomography scans were retrospectively analyzed, encompassing 1957 sinuses. Mucosal thickness (MT) and mucosal appearance (MA) were classified as normal, flat thickening, polypoid thickening, or ostium obstruction. Ostium width (OW), infundibulum length (IL), and ethmoidal bulla diameter (EBD) were measured. The presence of Haller cells (HC), concha bullosa (CB), and superior attachment of the uncinate process (UPSA) was recorded. Kruskal–Wallis, Mann–Whitney U, Chi-square, and GEE models were used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mucosal thickening was observed in 54% of the sinuses, with flat thickening (23.5%) being the most prevalent pattern. A significant association was found between ostium obstruction and MT greater than 10 mm. MT, IL, OW, and EBD values were significantly higher in men than in women. Significant correlations were also identified between MT and IL, OW, EBD, and HC. No significant relationship was found between CB and MT. However, UPSA types 3, 4, and 6 were significantly associated with polypoid thickening and ostium obstruction.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The findings demonstrate that anatomical variations in the OMC influence maxillary sinus membrane thickness. A comprehensive evaluation of these variations should be performed before planning for SFE procedures. Dentists should be proficient in identifying and assessing the osteomeatal region during routine radiographic examinations to prevent potential complications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145936705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Walid Elamrousy, Mohamed Marzok, Mohamed Nassar, Wael M. El-Deeb, Mahmoud Kandeel, Mohamed Y. Abdelfattah, Adel I. Almubarak, Zakriya Al Mohamad, Moustafa Abdou, Sherief M. Abdel-Raheem, Hamada Deyab, Ahmed I. Abdul-Aziz, Sayed El-Hawari, Dalia Rasheed Issa
<div> <section> <h3> Objectives</h3> <p>The current trial investigated the clinical and radiological effectiveness of utilizing un-demineralized autologous tooth graft as a graft material after ridge split and expansion approach combined with simultaneous dental implant placement compared to autologous bone graft (harvested from the chin) for reconstructing horizontally deficient alveolar ridges.</p> </section> <section> <h3> Materials and Methods</h3> <p>Fifty-two individuals with a total of 60 horizontally compromised alveolar ridge sites in the maxillary anterior region were recruited for this study. Participants were randomly assigned to two groups: the control group (each 30 implants in 26 patients) received autologous bone graft for peri-implant augmentation following ridge split and expansion with simultaneous implantation, while the study group used un-demineralized autologous tooth graft. Quotient of implant stability, horizontal ridge width, marginal bone level, vertical defect depth, and bone density was recorded and assessed throughout the study period.</p> </section> <section> <h3> Results</h3> <p>The Amount of Expansion of Both Groups Immediately After Surgery Revealed a Non-Significant Difference (B = 0.02, <i>p</i> = 0.760), while 12 Months Later a Significant Higher Ridge Expansion Values Was Observed in the UATG Group Over the ABG Group (B = 1.66, <i>p</i> < 0.001). The Implant Stability Quotient in the UATG Group Demonstrated a Significant Rise After 6- and 12-Months From Surgical Intervention Compared to the ABG Group as (B = 5.75, <i>p</i> < 0.001), (B = 7.46, <i>p</i> < 0.001) Respectively. Upon Comparing the Marginal Bone Loss, Non-Significant Difference Was Detected Either 6 or 12-Months Postoperatively (B = 0.03, <i>p</i> = 0.339, B = 0.03, <i>p</i> = 0.425, Respectively) The Peri-Implant Bone Defects in the UATG Group Showed Significantly Higher Bone-Fill Compared to the ABG Group by the End of the Study (B = −1.08, <i>p</i> < 0.001) Moreover, the UATG Group Demonstrated a Significant Gain in the Mean Bone Density After 6- and 12-Month Post-Surgically Over the ABG Group (B = 367.30, <i>p</i> < 0.001, B = 408.44, <i>p</i> < 0.001, Respectively).</p> </section> <section> <h3> Conclusions</h3> <p>Applying un-demineralized autologous tooth graft in bony defects surrounding implants after ridge split/expansion and simultaneous implantation for the reconstruction of ridge defects horizontally enhanced the peri-implant outcomes clinically and radiographically. As far as we know, this was the first attempt to utilize an un-demineralized autologous tooth graft with ridge split and expansion with
目的：本研究探讨了在牙槽嵴裂扩入路后，与自体骨移植（摘自下颌）重建水平缺损牙槽嵴相比，采用未脱矿化的自体牙移植物作为移植材料并同时植入种植体的临床和放射学效果。材料和方法：本研究招募了52名上颌前区60个水平受损的牙槽嵴部位的患者。参与者被随机分为两组：对照组（26例患者，每30颗种植体）接受自体骨移植进行种植体周围增强，同时种植脊裂和扩张，而研究组使用未脱矿的自体牙移植。在整个研究期间，记录并评估种植体稳定性、水平脊宽、边缘骨水平、垂直缺损深度和骨密度的商数。结果：两组术后即刻嵴扩张量差异无统计学意义（B = 0.02, p = 0.760）， 12个月后UATG组嵴扩张值明显高于ABG组（B = 1.66, p）。应用未脱矿化的自体牙移植物修复种植体嵴裂/扩张后周围骨缺损，同时种植修复种植体嵴缺损，水平提高了种植体周围的临床和影像学效果。据我们所知，这是第一次尝试使用非脱矿的自体牙移植物进行牙槽嵴分裂和扩张同时种植来重建侧受损的牙槽嵴缺陷。
{"title":"Maxillary Ridge Split and Expansion Augmented by Autologous Tooth Graft: Randomized Controlled Clinical Trial","authors":"Walid Elamrousy, Mohamed Marzok, Mohamed Nassar, Wael M. El-Deeb, Mahmoud Kandeel, Mohamed Y. Abdelfattah, Adel I. Almubarak, Zakriya Al Mohamad, Moustafa Abdou, Sherief M. Abdel-Raheem, Hamada Deyab, Ahmed I. Abdul-Aziz, Sayed El-Hawari, Dalia Rasheed Issa","doi":"10.1111/cid.70106","DOIUrl":"10.1111/cid.70106","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The current trial investigated the clinical and radiological effectiveness of utilizing un-demineralized autologous tooth graft as a graft material after ridge split and expansion approach combined with simultaneous dental implant placement compared to autologous bone graft (harvested from the chin) for reconstructing horizontally deficient alveolar ridges.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Fifty-two individuals with a total of 60 horizontally compromised alveolar ridge sites in the maxillary anterior region were recruited for this study. Participants were randomly assigned to two groups: the control group (each 30 implants in 26 patients) received autologous bone graft for peri-implant augmentation following ridge split and expansion with simultaneous implantation, while the study group used un-demineralized autologous tooth graft. Quotient of implant stability, horizontal ridge width, marginal bone level, vertical defect depth, and bone density was recorded and assessed throughout the study period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The Amount of Expansion of Both Groups Immediately After Surgery Revealed a Non-Significant Difference (B = 0.02, <i>p</i> = 0.760), while 12 Months Later a Significant Higher Ridge Expansion Values Was Observed in the UATG Group Over the ABG Group (B = 1.66, <i>p</i> < 0.001). The Implant Stability Quotient in the UATG Group Demonstrated a Significant Rise After 6- and 12-Months From Surgical Intervention Compared to the ABG Group as (B = 5.75, <i>p</i> < 0.001), (B = 7.46, <i>p</i> < 0.001) Respectively. Upon Comparing the Marginal Bone Loss, Non-Significant Difference Was Detected Either 6 or 12-Months Postoperatively (B = 0.03, <i>p</i> = 0.339, B = 0.03, <i>p</i> = 0.425, Respectively) The Peri-Implant Bone Defects in the UATG Group Showed Significantly Higher Bone-Fill Compared to the ABG Group by the End of the Study (B = −1.08, <i>p</i> < 0.001) Moreover, the UATG Group Demonstrated a Significant Gain in the Mean Bone Density After 6- and 12-Month Post-Surgically Over the ABG Group (B = 367.30, <i>p</i> < 0.001, B = 408.44, <i>p</i> < 0.001, Respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Applying un-demineralized autologous tooth graft in bony defects surrounding implants after ridge split/expansion and simultaneous implantation for the reconstruction of ridge defects horizontally enhanced the peri-implant outcomes clinically and radiographically. As far as we know, this was the first attempt to utilize an un-demineralized autologous tooth graft with ridge split and expansion with ","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bahaaeldeen M. Elgarba, Rocharles Cavalcante Fontenele, Eslam Abdelwahab Dawood, Pierre Lahoud, Jan Meeus, Reinhilde Jacobs
Objectives
To assess the clinical validity of artificial intelligence (AI)-driven virtual implant placement compared to human intelligence (HI)-based virtual and actual single implant placement in the posterior mandible.
Material and Methods
Thirty-two patients for whom experts performed single implant placement in the posterior mandible were included, each with preoperative and postoperative cone-beam computed tomography (CBCT) scans. The preoperative scans were registered to the corresponding postoperative scans and used for both AI- and HI-driven virtual implant planning at the implant site. From each case, three implants' scenarios (i.e., HI-placed, AI-planned, and HI-planned) were exported and compared. The analysis focused on angular deviation and the spatial relationship of each implant to adjacent anatomical structures and the expert-designed prosthetic wax-up. In addition, pairwise comparisons were performed to quantify angular and linear deviations at both the coronal and apical levels. Implant length and diameter from planned versus placed implants were evaluated, and planning time and consistency were compared between AI- and HI-based approaches.
Results
AI-based planning showed no statistically significant differences compared to HI-based methods observed in angular deviation relative to adjacent tooth (HI-placed: 7.7° ± 5.6°, AI: 6° ± 4.7°, HI-planned: 5.2° ± 5.7°) and coronal deviation (AI vs. HI-placed: 0.9 ± 0.8 mm, AI vs. HI-planned: 0.8 ± 0.4 mm, HI-planned vs. HI-placed: 1.0 ± 1.1 mm), all with p > 0.05. Implant diameter and length were also consistent across the different approaches, with HI-placed (4.3 ± 0.3 mm; 9.7 ± 1.3 mm), AI (4.3 ± 0.4 mm; 9.9 ± 1.2 mm), and HI-planned (4.3 ± 0.4 mm; 9.8 ± 1.3 mm) showing no significant differences (p > 0.05). However, AI planning was significantly faster (36.3 ± 7.3 s vs. 373 ± 113 s) and more consistent, with a median surface deviation of 0 mm compared to 0.39 mm for HI (p < 0.05).
Conclusion
The AI tool showed clinically valid implant selection, matched expert placement and planning in virtual implant positioning for missing mandibular premolars and molars while being highly consistent and 10 times faster compared to human expert planning.
目的：比较人工智能（AI）驱动的虚拟种植体与人工智能（HI）驱动的虚拟种植体和实际单种植体在后下颌的临床有效性。材料和方法：32例经专家在后下颌骨进行单种植体植入的患者，每个患者术前和术后都进行了锥形束计算机断层扫描（CBCT）。术前扫描记录到相应的术后扫描，并用于人工智能和高分辨率驱动的虚拟种植计划。从每个病例中，导出并比较三种种植体方案（即hi放置，ai计划和hi计划）。分析的重点是每个种植体与相邻解剖结构的角度偏差和空间关系，以及专家设计的假体上蜡。此外，两两比较进行量化角和线性偏差在冠状和根尖水平。评估计划种植体和放置种植体的长度和直径，并比较基于AI和基于hi的方法的计划时间和一致性。结果：人工智能规划与基于人工智能的方法相比，在相对于邻牙的角度偏差（hi - placement: 7.7°±5.6°，AI: 6°±4.7°，HI-planned: 5.2°±5.7°）和冠状偏差（AI vs. HI-planned: 0.9±0.8 mm, AI vs. HI-planned: 0.8±0.4 mm, HI-planned vs. hi - placement: 1.0±1.1 mm）方面，差异均无统计学意义，p < 0.05。种植体直径和长度在不同入路之间也一致，hi放置（4.3±0.3 mm; 9.7±1.3 mm）， AI（4.3±0.4 mm; 9.9±1.2 mm）和hi计划（4.3±0.4 mm; 9.8±1.3 mm）无显著差异（p > 0.05）。然而，人工智能计划明显更快（36.3±7.3秒比373±113秒），更一致，中位面偏差为0 mm，而HI为0.39 mm (p)。结论：人工智能工具在下颌前磨牙和磨牙缺失的虚拟种植体定位中显示临床有效的种植体选择，匹配专家放置和计划，高度一致，比人类专家计划快10倍。
{"title":"Clinical Feasibility of AI-Driven Automated Virtual Dental Implant Placement: A Cross-Sectional Comparative Study","authors":"Bahaaeldeen M. Elgarba, Rocharles Cavalcante Fontenele, Eslam Abdelwahab Dawood, Pierre Lahoud, Jan Meeus, Reinhilde Jacobs","doi":"10.1111/cid.70111","DOIUrl":"10.1111/cid.70111","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To assess the clinical validity of artificial intelligence (AI)-driven virtual implant placement compared to human intelligence (HI)-based virtual and actual single implant placement in the posterior mandible.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Thirty-two patients for whom experts performed single implant placement in the posterior mandible were included, each with preoperative and postoperative cone-beam computed tomography (CBCT) scans. The preoperative scans were registered to the corresponding postoperative scans and used for both AI- and HI-driven virtual implant planning at the implant site. From each case, three implants' scenarios (i.e., HI-placed, AI-planned, and HI-planned) were exported and compared. The analysis focused on angular deviation and the spatial relationship of each implant to adjacent anatomical structures and the expert-designed prosthetic wax-up. In addition, pairwise comparisons were performed to quantify angular and linear deviations at both the coronal and apical levels. Implant length and diameter from planned versus placed implants were evaluated, and planning time and consistency were compared between AI- and HI-based approaches.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>AI-based planning showed no statistically significant differences compared to HI-based methods observed in angular deviation relative to adjacent tooth (HI-placed: 7.7° ± 5.6°, AI: 6° ± 4.7°, HI-planned: 5.2° ± 5.7°) and coronal deviation (AI vs. HI-placed: 0.9 ± 0.8 mm, AI vs. HI-planned: 0.8 ± 0.4 mm, HI-planned vs. HI-placed: 1.0 ± 1.1 mm), all with <i>p</i> > 0.05. Implant diameter and length were also consistent across the different approaches, with HI-placed (4.3 ± 0.3 mm; 9.7 ± 1.3 mm), AI (4.3 ± 0.4 mm; 9.9 ± 1.2 mm), and HI-planned (4.3 ± 0.4 mm; 9.8 ± 1.3 mm) showing no significant differences (<i>p</i> > 0.05). However, AI planning was significantly faster (36.3 ± 7.3 s vs. 373 ± 113 s) and more consistent, with a median surface deviation of 0 mm compared to 0.39 mm for HI (<i>p</i> < 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The AI tool showed clinically valid implant selection, matched expert placement and planning in virtual implant positioning for missing mandibular premolars and molars while being highly consistent and 10 times faster compared to human expert planning.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12722112/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145812439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To evaluate the accuracy of dental implant placement using fully guided static computer-assisted implant surgery (s-CAIS) and autonomous robotic computer-assisted implant surgery (r-CAIS) technology in patients with transcrestal sinus floor elevation.
Materials and Methods
Patients with posterior teeth loss and transcrestal sinus floor elevation using s-CAIS or r-CAIS technology for implant surgery were included in this study. A total of 34 patients with 42 implants were included in the study (17 patients with 19 implants in the autonomous r-CAIS group, 17 patients with 23 implants in the fully guided s-CAIS group). Postoperative cone-beam computed tomography (CBCT) scans were used to determine the discrepancies between the planned and actually placed implants. The preoperative and postoperative CBCT were utilized to estimate the linear deviations and angular deviations in two-dimensional (2D) and three-dimensional (3D) space.
Results
A total of 42 implants were included, with significant differences between the autonomous r-CAIS group and fully guided s-CAIS group (p < 0.001). No adverse surgical events occurred. The 3D deviations at the implant platform were 0.484 ± 0.218 mm for the autonomous r-CAIS group and 1.179 ± 0.776 mm for the fully guided s-CAIS group, respectively. The mean linear deviations at the implant apex were 0.527 ± 0.247 and 1.196 ± 0.830 mm, respectively. The mean angular deviation was 0.882° ± 0.967° for the autonomous r-CAIS group and 2.478° ± 1.524° for the fully guided s-CAIS group.
Conclusions
Autonomous r-CAIS technology provided a more accurate surgical approach for implant placement in patients with transcrestal sinus floor elevation than fully guided s-CAIS.
{"title":"Accuracy of Robotic Vesus Fully Guided Static Computer-Assisted Implant Surgery With Transcrestal Sinus Floor Elevation","authors":"Qinmeng Zhang, Yuesheng Qiu, Ling Hu, Danhong Zhou, Zichun Xia, Guoli Yang, Zhiwei Jiang","doi":"10.1111/cid.70113","DOIUrl":"10.1111/cid.70113","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the accuracy of dental implant placement using fully guided static computer-assisted implant surgery (s-CAIS) and autonomous robotic computer-assisted implant surgery (r-CAIS) technology in patients with transcrestal sinus floor elevation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients with posterior teeth loss and transcrestal sinus floor elevation using s-CAIS or r-CAIS technology for implant surgery were included in this study. A total of 34 patients with 42 implants were included in the study (17 patients with 19 implants in the autonomous r-CAIS group, 17 patients with 23 implants in the fully guided s-CAIS group). Postoperative cone-beam computed tomography (CBCT) scans were used to determine the discrepancies between the planned and actually placed implants. The preoperative and postoperative CBCT were utilized to estimate the linear deviations and angular deviations in two-dimensional (2D) and three-dimensional (3D) space.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 42 implants were included, with significant differences between the autonomous r-CAIS group and fully guided s-CAIS group (<i>p</i> < 0.001). No adverse surgical events occurred. The 3D deviations at the implant platform were 0.484 ± 0.218 mm for the autonomous r-CAIS group and 1.179 ± 0.776 mm for the fully guided s-CAIS group, respectively. The mean linear deviations at the implant apex were 0.527 ± 0.247 and 1.196 ± 0.830 mm, respectively. The mean angular deviation was 0.882° ± 0.967° for the autonomous r-CAIS group and 2.478° ± 1.524° for the fully guided s-CAIS group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Autonomous r-CAIS technology provided a more accurate surgical approach for implant placement in patients with transcrestal sinus floor elevation than fully guided s-CAIS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145806743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This prospective multicenter study evaluated the 5-year clinical performance of one-piece, long, smooth-necked narrow-diameter implants (NDIs) in rehabilitating patients with congenital maxillary lateral incisor agenesis and limited alveolar bone.
Materials and Methods
Patients aged ≥ 18 years with unilateral or bilateral agenesis and mesiodistal spaces of 3.5–5.5 mm were recruited. Flapless implant placement of Ø2.7 mm, smooth-necked implants was performed, followed by immediate loading with lithium disilicate crowns. Radiographic assessments of marginal bone levels, peri-implant soft tissue parameters, and esthetic outcomes were conducted at baseline, 1 month, 1 year, and 5 years. Implant survival, success, and mechanical/biological complications were systematically recorded. Statistical analyses employed Kaplan–Meier survival curves and ANOVA with significance set at p < 0.05.
Results
Forty-six patients completed the 5-year follow-up. Implant survival and success rates were 97.8% and 93.5%, respectively. Mean marginal bone loss was 0.43 ± 0.06 mm at 1 year and 0.84 ± 0.11 mm at 5 years. Probing depths and bleeding indices remained within normal limits (2.96 ± 0.1 mm at 5 years). Papilla preservation was achieved in 89% of cases, and pink esthetic scores indicated stable soft tissue integration. Mechanical complications were minimal, with two cementation failures and one minor ceramic chipping; no implant or abutment fractures occurred.
Conclusions
One-piece NDIs represent a reliable, esthetic, and cost-effective treatment option for maxillary lateral incisor agenesis in patients with limited alveolar dimensions. High survival, minimal bone loss, stable soft tissue, and low complication rates support their use as a minimally invasive, patient-centered solution.
{"title":"Five-Year Multicenter Study on One-Piece Narrow Implants for Congenitally Missing Maxillary Lateral Incisors","authors":"Zaid Hamdoon, Ahmad Aziz, Waad Kheder, Mohamad Haki, Shishir Shetty, Waseem Jerjes","doi":"10.1111/cid.70116","DOIUrl":"10.1111/cid.70116","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This prospective multicenter study evaluated the 5-year clinical performance of one-piece, long, smooth-necked narrow-diameter implants (NDIs) in rehabilitating patients with congenital maxillary lateral incisor agenesis and limited alveolar bone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients aged ≥ 18 years with unilateral or bilateral agenesis and mesiodistal spaces of 3.5–5.5 mm were recruited. Flapless implant placement of Ø2.7 mm, smooth-necked implants was performed, followed by immediate loading with lithium disilicate crowns. Radiographic assessments of marginal bone levels, peri-implant soft tissue parameters, and esthetic outcomes were conducted at baseline, 1 month, 1 year, and 5 years. Implant survival, success, and mechanical/biological complications were systematically recorded. Statistical analyses employed Kaplan–Meier survival curves and ANOVA with significance set at <i>p</i> < 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-six patients completed the 5-year follow-up. Implant survival and success rates were 97.8% and 93.5%, respectively. Mean marginal bone loss was 0.43 ± 0.06 mm at 1 year and 0.84 ± 0.11 mm at 5 years. Probing depths and bleeding indices remained within normal limits (2.96 ± 0.1 mm at 5 years). Papilla preservation was achieved in 89% of cases, and pink esthetic scores indicated stable soft tissue integration. Mechanical complications were minimal, with two cementation failures and one minor ceramic chipping; no implant or abutment fractures occurred.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>One-piece NDIs represent a reliable, esthetic, and cost-effective treatment option for maxillary lateral incisor agenesis in patients with limited alveolar dimensions. High survival, minimal bone loss, stable soft tissue, and low complication rates support their use as a minimally invasive, patient-centered solution.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145811776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Digital Treatment Planning, Robotics, and Artificial Intelligence for Implant Therapy","authors":"Jia Hui Fu, Tim Joda","doi":"10.1111/cid.70114","DOIUrl":"10.1111/cid.70114","url":null,"abstract":"","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145776530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to systematically compare the efficacy and resorption of in-situ and ex-situ bone onlay grafting in reconstructing horizontal alveolar ridge defects of anterior teeth.
Methods
One-hundred and twenty five patients receiving autogenous bone onlay grafts in the anterior tooth region were included in this study, which comprised 55 patients with 66 implants receiving in-situ bone grafts (in-situ group) and 70 patients with 77 implants receiving ex-situ bone grafts (ex-situ group). All patients were examined by CBCT scanning before bone augmentation (T0), immediately after bone augmentation (T1), at 5–8 months after bone augmentation (T2), immediately after implant placement (T3), and 5–8 months after implant placement (T4). Horizontal bone width (HBW) and bone volume (BV) were measured at different postoperative time points after automated image registration of consecutive CBCT imaging.
Results
The resorption rate of HBW from T1 to T2 in the in-situ group (23.84% ± 17.07%) was significantly lower than that in the ex-situ group (38.77% ± 19.94%) (p < 0.0001). However, from T3 to T4, no significant difference was observed between the two groups. Additionally, from T1 to T2, there were significant differences in the resorption rate of BV between the in-situ group (20.03% ± 16.14%) and the ex-situ group (28.20% ± 17.58%) (p < 0.05). In contrast, no significant differences between the two groups from T3 to T4 were noted.
Conclusions
Both in-situ and ex-situ onlay graftings showed a satisfactory outcome in bone augmentation, yet in-situ bone graft had more bone augmentation and better stability than ex-situ bone graft.
{"title":"In-Situ vs. Ex-Situ Bone Onlay Grafting for Horizontal Ridge Augmentation of Anterior Teeth: A Retrospective Study","authors":"Kejie Lu, Lidan Huang, Jiaxing Gong, Ying Qian, Xiaofu Yang, Mengfei Yu, Huiming Wang","doi":"10.1111/cid.70107","DOIUrl":"10.1111/cid.70107","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to systematically compare the efficacy and resorption of in-situ and ex-situ bone onlay grafting in reconstructing horizontal alveolar ridge defects of anterior teeth.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>One-hundred and twenty five patients receiving autogenous bone onlay grafts in the anterior tooth region were included in this study, which comprised 55 patients with 66 implants receiving in-situ bone grafts (in-situ group) and 70 patients with 77 implants receiving ex-situ bone grafts (ex-situ group). All patients were examined by CBCT scanning before bone augmentation (T0), immediately after bone augmentation (T1), at 5–8 months after bone augmentation (T2), immediately after implant placement (T3), and 5–8 months after implant placement (T4). Horizontal bone width (HBW) and bone volume (BV) were measured at different postoperative time points after automated image registration of consecutive CBCT imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The resorption rate of HBW from T1 to T2 in the in-situ group (23.84% ± 17.07%) was significantly lower than that in the ex-situ group (38.77% ± 19.94%) (<i>p</i> < 0.0001). However, from T3 to T4, no significant difference was observed between the two groups. Additionally, from T1 to T2, there were significant differences in the resorption rate of BV between the in-situ group (20.03% ± 16.14%) and the ex-situ group (28.20% ± 17.58%) (<i>p</i> < 0.05). In contrast, no significant differences between the two groups from T3 to T4 were noted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Both in-situ and ex-situ onlay graftings showed a satisfactory outcome in bone augmentation, yet in-situ bone graft had more bone augmentation and better stability than ex-situ bone graft.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 6","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145770276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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