{"title":"Moving towards precision psychiatry: the hard nut of depression","authors":"Juergen Dukart, Leon D. Lotter, Simon B. Eickhoff","doi":"10.1038/s41392-024-02023-8","DOIUrl":null,"url":null,"abstract":"<p>In a recent study published in <i>Nature</i>, Lynch et al.<sup>1</sup> reported a consistent spatial expansion of the resting state salience network in subjects with major depression. The expansion was already present in children who later developed depression and remained stable over time in patients with depression, indicating a trait-like behavior of the observed endophenotype.</p>","PeriodicalId":21766,"journal":{"name":"Signal Transduction and Targeted Therapy","volume":null,"pages":null},"PeriodicalIF":40.8000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Signal Transduction and Targeted Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41392-024-02023-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In a recent study published in Nature, Lynch et al.1 reported a consistent spatial expansion of the resting state salience network in subjects with major depression. The expansion was already present in children who later developed depression and remained stable over time in patients with depression, indicating a trait-like behavior of the observed endophenotype.
期刊介绍：
Signal Transduction and Targeted Therapy is an open access journal that focuses on timely publication of cutting-edge discoveries and advancements in basic science and clinical research related to signal transduction and targeted therapy.
Scope: The journal covers research on major human diseases, including, but not limited to:
Cancer,Cardiovascular diseases,Autoimmune diseases,Nervous system diseases.
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