Effect of reduced flaxseed cyclic peptide [1–9-NαC]-linusorb B2 (CLB) and its oxidized form on the oxidative stability of flaxseed oil

IF 5.4 2区医学 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Biomaterials Science & Engineering Pub Date : 2024-11-12 DOI:10.1016/j.foodchem.2024.142011

Shilu Deng, Jing Li, Ting Luo, Liufeng Zheng, Zeyuan Deng

引用次数: 0

Abstract

This study aimed to explore the antioxidant capacity and mechanism of cyclic peptide [1–9-NαC]-linusorb B2 (CLB) and its oxidized form ([1–9-NαC],[1-MetO]-linusorb B2 (CLC),[1–9-NαC],[1-MetO2]-linusorb B2 (CLK)) in flaxseed oil (FSO). The results showed that CLB delayed the oxidation of FSO (containing Cu²⁺) in the initial stage of accelerated oxidation, whereas CLK accelerated the oxidation, leading to an increase of 25 % in AV and 33 % in POV (P < 0.05). In molecular docking, the binding ability of cyclic peptides to metal ions and intermediate oxidative products such as aldehydes tends to decrease when CLB oxidized to CLC, then CLK. CLK had the poorest binding capacity with the most serious oxidation on FSO. In conclusion, the antioxidant capacities of CLB and its oxidized form were contributed by their reducing ability as well as their binding ability to metal ions and intermediate oxidative products of fatty acids.

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还原亚麻籽环肽 [1-9-NαC]-linusorb B2 (CLB) 及其氧化形式对亚麻籽油氧化稳定性的影响

本研究旨在探讨亚麻籽油（FSO）中环肽[1-9-NαC]-linusorb B2（CLB）及其氧化形式（[1-9-NαC], [1-MetO]-linusorb B2 (CLC)、[1-9-NαC], [1-MetO2]-linusorb B2 (CLK)）的抗氧化能力和机理。结果表明，在加速氧化的初始阶段，CLB 能延缓 FSO（含 Cu2+）的氧化，而 CLK 则能加速氧化，使 AV 值增加 25%，POV 值增加 33%（P <0.05）。在分子对接中，当 CLB 氧化为 CLC 时，环肽与金属离子和中间氧化产物（如醛类）的结合能力呈下降趋势，然后是 CLK。CLK 的结合能力最差，对 FSO 的氧化作用最严重。总之，CLB 及其氧化形式的抗氧化能力取决于其还原能力以及与金属离子和脂肪酸中间氧化产物的结合能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Biomaterials Science & Engineering Materials Science-Biomaterials

CiteScore

10.30

自引率

3.40%

发文量

413

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