Advancing extracorporeal carbon dioxide removal technology: bridging basic science and clinical practice.

IF 3 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Medical Gas Research Pub Date : 2024-11-08 DOI:10.4103/mgr.MEDGASRES-D-24-00051
Sergio Lassola, Denise Battaglini, Silvia De Rosa
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Abstract

Recently, advancements in extracorporeal carbon dioxide removal (ECCO2R) technology have markedly enhanced its clinical applicability and efficacy for managing severe respiratory conditions. This review highlights critical innovations in ECCO2R, such as advanced catheter technologies, active mixing methods, and biochemical enhancements, which have substantially improved gas exchange efficiency and broadened the scope of ECCO2R applications. Integrating ECCO2R into acute and chronic respiratory care has led to a shift toward more mobile and less invasive modalities, promising for extending ECCO2R usage from intensive care units to home settings. By examining these technological advancements and their clinical impacts, this paper outlines the potential future directions of ECCO2R technology, emphasizing its role in transforming respiratory care practices and enhancing patient outcomes.

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推进体外二氧化碳清除技术:连接基础科学与临床实践。
最近,体外二氧化碳清除(ECCO2R)技术的进步明显提高了其临床应用性和治疗严重呼吸系统疾病的效果。本综述重点介绍了 ECCO2R 的关键创新技术,如先进的导管技术、主动混合方法和生化增强技术,这些技术大大提高了气体交换效率,扩大了 ECCO2R 的应用范围。将 ECCO2R 纳入急性和慢性呼吸道护理已导致向移动性更强、侵入性更小的模式转变,有望将 ECCO2R 的应用从重症监护室扩展到家庭环境。通过研究这些技术进步及其临床影响,本文概述了 ECCO2R 技术未来的潜在发展方向,强调了它在改变呼吸护理实践和提高患者疗效方面的作用。
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来源期刊
Medical Gas Research
Medical Gas Research MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.10
自引率
13.80%
发文量
35
期刊介绍: Medical Gas Research is an open access journal which publishes basic, translational, and clinical research focusing on the neurobiology as well as multidisciplinary aspects of medical gas research and their applications to related disorders. The journal covers all areas of medical gas research, but also has several special sections. Authors can submit directly to these sections, whose peer-review process is overseen by our distinguished Section Editors: Inert gases - Edited by Xuejun Sun and Mark Coburn, Gasotransmitters - Edited by Atsunori Nakao and John Calvert, Oxygen and diving medicine - Edited by Daniel Rossignol and Ke Jian Liu, Anesthetic gases - Edited by Richard Applegate and Zhongcong Xie, Medical gas in other fields of biology - Edited by John Zhang. Medical gas is a large family including oxygen, hydrogen, carbon monoxide, carbon dioxide, nitrogen, xenon, hydrogen sulfide, nitrous oxide, carbon disulfide, argon, helium and other noble gases. These medical gases are used in multiple fields of clinical practice and basic science research including anesthesiology, hyperbaric oxygen medicine, diving medicine, internal medicine, emergency medicine, surgery, and many basic sciences disciplines such as physiology, pharmacology, biochemistry, microbiology and neurosciences. Due to the unique nature of medical gas practice, Medical Gas Research will serve as an information platform for educational and technological advances in the field of medical gas.
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