Rev or restrain: Mechanisms of human-specific synaptic neoteny.

IF 15 1区 医学 Q1 NEUROSCIENCES Neuron Pub Date : 2024-11-06 DOI:10.1016/j.neuron.2024.10.011
Jenelle L Wallace, Alex A Pollen
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引用次数: 0

Abstract

In the current issues of Neuron and Cell Reports, Libé-Philippot et al.1 and Assendorp et al.2 identify interactions between human-specific SRGAP2C, synaptic regulator SRGAP2A, and neurodevelopmental disorder-associated proteins SYNGAP1 and CTNND2 that slow synaptic maturation in human neurons.

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修正或抑制:人类特异性突触新生的机制。
在本期《神经元与细胞报告》(Neuron and Cell Reports)上,Libé-Philippot 等人1 和 Assendorp 等人2 发现了人类特异性 SRGAP2C、突触调节因子 SRGAP2A 以及神经发育障碍相关蛋白 SYNGAP1 和 CTNND2 之间的相互作用,这些相互作用减缓了人类神经元的突触成熟。
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来源期刊
Neuron
Neuron 医学-神经科学
CiteScore
24.50
自引率
3.10%
发文量
382
审稿时长
1 months
期刊介绍: Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.
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