Shiva Pakzad, Reza Taghavi, Amir Hasanzadeh and Sadegh Rostamnia
{"title":"A biocompatible cellulose gum based CMC/PVA/SBA-15 film as a colloidal antibacterial agent against MRSA†","authors":"Shiva Pakzad, Reza Taghavi, Amir Hasanzadeh and Sadegh Rostamnia","doi":"10.1039/D4RA07129H","DOIUrl":null,"url":null,"abstract":"<p >The development of biocompatible antibacterial films plays a crucial role in the fight against antibiotic-resistant bacteria strains. Here, we developed an SBA-15–NH<small><sub>2</sub></small> decorated biocompatible CMC/PVA film containing Ag NPs as an antibacterial material against Gram-positive and Gram-negative bacteria strains. The structure of the manufactured film was studied by XRD, SEM, mapping, and TGA analysis showing its formation and firm structure. The prepared film has a flexible structure which makes it suitable for a variety of bio-related applications. The CMC/PVA/SBA-15–NH<small><sub>2</sub></small>@AgNPs film was used as a bactericidal agent against pathogens (especially MRSA; methicillin-resistant <em>Staphylococcus aureus</em>) isolated from surgical site infections, showing promising results.</p>","PeriodicalId":102,"journal":{"name":"RSC Advances","volume":" 49","pages":" 36246-36252"},"PeriodicalIF":3.9000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559378/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"RSC Advances","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra07129h","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
The development of biocompatible antibacterial films plays a crucial role in the fight against antibiotic-resistant bacteria strains. Here, we developed an SBA-15–NH2 decorated biocompatible CMC/PVA film containing Ag NPs as an antibacterial material against Gram-positive and Gram-negative bacteria strains. The structure of the manufactured film was studied by XRD, SEM, mapping, and TGA analysis showing its formation and firm structure. The prepared film has a flexible structure which makes it suitable for a variety of bio-related applications. The CMC/PVA/SBA-15–NH2@AgNPs film was used as a bactericidal agent against pathogens (especially MRSA; methicillin-resistant Staphylococcus aureus) isolated from surgical site infections, showing promising results.
期刊介绍：
An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.
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