Enhancing Male Fertility Through AI-Based Management of Varicoceles.

IF 2.5 2区 医学 Q2 UROLOGY & NEPHROLOGY Current Urology Reports Pub Date : 2024-11-11 DOI:10.1007/s11934-024-01241-5
Zhongwei Huang, Germar-M Pinggera, Ashok Agarwal
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Abstract

Review purpose: The clinical management of subclinical and symptomatic varicoceles in male infertility remains challenging. Current guidelines focus on treating men with abnormal semen analyses, but a more precise approach to identify, stratify, and prognosticate men with varicoceles and fertility issues is essential.

Recent findings: Multiple studies have utilized Artificial Intelligence (AI) to analyze clinical-demographic characteristics, semen analyses, pre-operative imaging findings, and intra-operative clinical data. These AI-driven approaches aim to discover novel biomarkers that can assess, stratify, and prognosticate men with subclinical and symptomatic varicoceles requiring early intervention. These sophisticated methodologies offer new insights and strategies for understanding normal spermatogenesis and the pathophysiology of varicocele-related male infertility. The application of AI strategies is expected to revolutionize varicocele management, enhancing male fertility and optimizing reproductive outcomes.

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通过人工授精治疗精索静脉曲张提高男性生育能力。
综述目的:男性不育症中亚临床和无症状精索静脉曲张的临床治疗仍具有挑战性。目前的指南侧重于治疗精液分析异常的男性,但有必要采用更精确的方法对患有精索静脉曲张和生育问题的男性进行识别、分层和预后:多项研究利用人工智能(AI)分析临床人口学特征、精液分析、术前成像结果和术中临床数据。这些人工智能驱动的方法旨在发现新的生物标志物,从而对需要早期干预的亚临床和无症状精索静脉曲张男性患者进行评估、分层和预后。这些复杂的方法为了解正常精子发生和精索静脉曲张相关男性不育的病理生理学提供了新的见解和策略。人工智能策略的应用有望彻底改变精索静脉曲张的治疗,提高男性生育能力并优化生殖结果。
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来源期刊
Current Urology Reports
Current Urology Reports UROLOGY & NEPHROLOGY-
CiteScore
4.60
自引率
3.80%
发文量
39
期刊介绍: This journal intends to review the most important, recently published findings in the field of urology. By providing clear, insightful, balanced contributions by international experts, the journal elucidates current and emerging approaches to the care and prevention of urologic diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as benign prostatic hyperplasia, erectile dysfunction, female urology, and kidney disease. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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