An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil.

IF 1.9 4区 医学 Q3 DERMATOLOGY Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-11-05 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S470989
Nouf F Bin Rubaian, Haya Fahad Abdulaziz Alzamami, Baraa Abdulrazack Amir
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Abstract

Androgenetic alopecia is a chronic dermatological condition in which genetically predisposed individuals undergo progressive hair loss secondary to the effects of circulating androgens. It has been well documented that dihydrotestosterone binds to the androgenic receptors prevalent in the scalp, thus inducing miniaturization of the hair follicle. To date, the only FDA approved medications for the treatment of androgenetic alopecia are finasteride and minoxidil. A plethora of studies have been conducted testing the efficacy of various herbal compounds, but additional research is needed to further establish the concrete efficacy of such natural remedies in treating androgenetic alopecia. Of late, rosemary oil has gained mass popularity as a promising natural alternative. This review article will not only provide a detailed background on this ancient herbal component but will additionally overview all other major herbal alternatives including peppermint oil, tea tree oil, green tea, pumpkin seed oil, saw palmetto, and lavender oil and will summarize the latest clinical studies, which have tested their efficacy for the management of androgenetic alopecia.

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治疗雄激素性脱发的常用天然替代品概述,特别强调迷迭香精油。
雄激素性脱发是一种慢性皮肤病,具有遗传易感性的人在循环雄激素的作用下会出现进行性脱发。有充分证据表明,双氢睾酮会与头皮中普遍存在的雄激素受体结合,从而导致毛囊小型化。迄今为止,美国食品及药物管理局批准用于治疗雄激素性脱发的药物只有非那雄胺和米诺地尔。已有大量研究对各种草药化合物的疗效进行了测试,但要进一步确定这些天然疗法治疗雄激素性脱发的具体疗效,还需要进行更多的研究。最近,迷迭香精油作为一种很有前景的天然替代品受到了大众的欢迎。这篇综述文章不仅将详细介绍这种古老草药成分的背景,还将概述所有其他主要草药替代品,包括薄荷油、茶树油、绿茶、南瓜籽油、锯棕榈和薰衣草油,并将总结最新的临床研究,这些研究已经测试了它们在治疗雄激素性脱发方面的功效。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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