Is routine screening for Candida auris necessary in ICU?

IF 1.3 Q4 MICROBIOLOGY Iranian Journal of Microbiology Pub Date : 2024-10-01 DOI:10.18502/ijm.v16i5.16807

Arun Sachu, Harisree Sudersanan, Sanjo Sunny, Philip Mathew, Ajeesh Kumar, Alice David

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Abstract

Background and objectives: The capability to cause invasive infection, multi-drug resistance, and health care-associated outbreaks of Candida auris have made it a pathogen of great concern. Estimating how many patients in our intensive care unit had C. auris colonization and what characteristics put patients at risk for having Candida spp. colonization were the primary goals of the study.

Materials and methods: Swabs from axilla and groin were collected from 229 patients getting admitted to the ICU. Samples were inoculated into CHROMagar^TM Candida Plus medium. Colonies presumptively identified as C. auris by the presence of light blue with blue halo and were confirmed by VITEK-2.

Results: Our study showed that only one patient was colonized with C. auris. A total of 47 (20.5%) patients were colonized with Candida spp., of which Candida parapislosis was the predominant organism. History of antibiotic use and cerebrovascular accident were independent risk factors in Candida colonization.

Conclusion: Active screening for Candida auris in all patients is not required in our hospital as the prevalence was very low and not cost-effective. Therefore we plan to modify our screening strategy and use risk factors based surveillance strategy as it may serve as an ideal strategy.

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重症监护病房是否有必要对念珠菌进行常规筛查？

背景和目的：念珠菌可引起侵袭性感染、多重耐药性以及与医疗保健相关的疫情爆发，这使其成为一种备受关注的病原体。本研究的主要目的是估算重症监护病房中有多少患者有念珠菌定植，以及哪些特征会导致患者有念珠菌定植的风险：从 229 名重症监护室住院患者的腋窝和腹股沟处采集拭子。将样本接种到 CHROMagarTM Candida Plus 培养基中。结果显示，只有一名患者被确诊为白色念珠菌感染：我们的研究表明，只有一名患者体内有念珠菌菌落。共有 47 名患者（20.5%）定植了念珠菌属，其中副咽峡炎念珠菌是主要病原菌。使用抗生素史和脑血管意外是念珠菌定植的独立风险因素：结论：在我们医院，不需要对所有患者进行积极的念珠菌筛查，因为念珠菌的流行率很低，而且不符合成本效益。因此，我们计划修改筛查策略，采用基于风险因素的监测策略，因为这可能是一种理想的策略。

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.