Endoscopic cardiac mucosal ligation: a novel minimally invasive procedure for gastroesophageal reflux disease.

IF 1.7 4区医学 Q2 SURGERY Minimally Invasive Therapy & Allied Technologies Pub Date : 2024-11-15 DOI:10.1080/13645706.2024.2417415

Yi Liu, Keshu Shan, Yonghong Xia, Lei Xu

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Abstract

Background: Our objective in this study was to evaluate the short-term clinical efficacy and safety of endoscopic cardiac mucosal ligation, a novel endoscopic procedure, in the treatment of gastroesophageal reflux disease (GERD).

Methods: Patients diagnosed with refractory GERD or recurrent patients due to drug withdrawal admitted to our hospital were recruited in this clinical trial. All GERD patients were treated with endoscopic cardiac mucosal ligation. Postoperatively, all patients received subsequent follow-ups for approximately four months to evaluate the efficacy and safety of this endoscopic procedure.

Results: A total of 13 GERD patients were enrolled. Endoscopic cardiac mucosal ligation was successfully performed in all cases. Postoperatively, relevant symptoms were significantly alleviated in 10 patients (76.9%). The average Gastroesophageal Reflux Disease Questionnaire (GERD-Q) score in all participants significantly decreased from preoperative 10.0 ± 3.5 to postoperative 7.8 ± 2.9 (p = .022). The average GERD symptom questionnaire score was 27.0 ± 12.0 prior to surgery, which significantly decreased to 18.3 ± 7.5 postoperatively (p = .032). No severe postoperative complications were observed during subsequent follow-ups.

Conclusions: Endoscopic cardiac mucosal ligation might be a novel effective and safe endoscopic procedure for GERD.

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内镜下心脏粘膜结扎术：治疗胃食管反流病的新型微创手术。

研究背景本研究旨在评估内镜下心脏粘膜结扎术（一种新型内镜手术）治疗胃食管反流病（GERD）的短期临床疗效和安全性：本临床试验招募了本院收治的难治性胃食管反流病患者或因停药而复发的患者。所有胃食管反流病患者都接受了内镜下心脏粘膜结扎术。术后，所有患者都接受了约四个月的随访，以评估这种内镜手术的疗效和安全性：结果：共有 13 名胃食管反流病患者入选。结果：共有 13 名胃食管反流患者接受了治疗，所有病例均成功实施了内镜下心脏粘膜结扎术。术后，10 名患者（76.9%）的相关症状明显缓解。所有参与者的胃食管反流病问卷（GERD-Q）平均得分从术前的 10.0 ± 3.5 显著降至术后的 7.8 ± 2.9（p = .022）。术前胃食管反流症状问卷的平均得分为 27.0 ± 12.0，术后明显降低到 18.3 ± 7.5（p = .032）。在随后的随访中未发现严重的术后并发症：结论：内镜下心脏粘膜结扎术可能是治疗胃食管反流病的一种有效、安全的新型内镜手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minimally Invasive Therapy & Allied Technologies 医学-外科

CiteScore

3.80

自引率

5.90%

发文量

审稿时长

6-12 weeks

期刊介绍： Minimally Invasive Therapy and Allied Technologies (MITAT) is an international forum for endoscopic surgeons, interventional radiologists and industrial instrument manufacturers. It is the official journal of the Society for Medical Innovation and Technology (SMIT) whose membership includes representatives from a broad spectrum of medical specialities, instrument manufacturing and research. The journal brings the latest developments and innovations in minimally invasive therapy to its readers. What makes Minimally Invasive Therapy and Allied Technologies unique is that we publish one or two special issues each year, which are devoted to a specific theme. Key topics covered by the journal include: interventional radiology, endoscopic surgery, imaging technology, manipulators and robotics for surgery and education and training for MIS.