Efficacy of honey suppositories in treating paediatric functional constipation: A comparative study.

IF 1.6 4区 医学 Q2 PEDIATRICS Journal of paediatrics and child health Pub Date : 2024-11-14 DOI:10.1111/jpc.16722
Guili Yu, Jing Gao, Jinglian Gu, Huazhen Li, Xiaoying Wang, Hui Bian
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Abstract

Aim: This study sought to assess the clinical efficacy of honey suppositories in managing functional constipation in pre-school children, with a focus on those exhibiting Yin deficiency and intestinal dryness according to traditional Chinese medicine principles. The investigation aimed to determine whether honey suppositories could serve as a safer and more efficacious alternative to standard treatments.

Methods: A randomised controlled trial was conducted involving pre-school children diagnosed with functional constipation. They were allocated to either a control group or a treatment group. While both groups received standard care, the treatment group also received honey suppositories. The efficacy of the treatment was evaluated based on the 'Guiding Principles for Clinical Research of New Chinese Medicines', and statistical analysis was performed using SPSS 25.0.

Results: Following treatment, the treatment group demonstrated significantly lower constipation scoring system scores and higher bowel movement frequencies compared with the control group (P < 0.05). The clinical efficacy of the treatment group was notably superior, with a higher rate of complete recovery and effectiveness observed (P < 0.05). Additionally, no significant differences in baseline characteristics were found between the groups, confirming the comparability of the study cohorts.

Conclusions: Honey suppositories offer a promising therapeutic intervention for paediatric functional constipation, with significant clinical benefits over standard care.

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蜂蜜栓剂治疗小儿功能性便秘的疗效:比较研究。
目的:本研究旨在评估蜂蜜栓剂在治疗学龄前儿童功能性便秘方面的临床疗效,重点是根据传统中医原理治疗阴虚肠燥的学龄前儿童。调查的目的是确定蜂蜜栓剂能否作为标准疗法的一种更安全、更有效的替代疗法:方法:对被诊断为功能性便秘的学龄前儿童进行随机对照试验。他们被分配到对照组或治疗组。对照组和治疗组都接受标准治疗,但治疗组还使用了蜂蜜栓剂。根据《中药新药临床研究指导原则》评价疗效,并使用 SPSS 25.0 进行统计分析:治疗后,与对照组相比,治疗组的便秘评分系统得分明显降低,排便次数明显增加(P 结论:蜂蜜栓剂具有良好的治疗效果:蜂蜜栓剂是治疗小儿功能性便秘的一种很有前景的干预措施,与标准疗法相比具有明显的临床疗效。
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来源期刊
CiteScore
2.90
自引率
5.90%
发文量
487
审稿时长
3-6 weeks
期刊介绍: The Journal of Paediatrics and Child Health publishes original research articles of scientific excellence in paediatrics and child health. Research Articles, Case Reports and Letters to the Editor are published, together with invited Reviews, Annotations, Editorial Comments and manuscripts of educational interest.
期刊最新文献
Issue Information Efficacy of honey suppositories in treating paediatric functional constipation: A comparative study. Hip surveillance in cerebral palsy: Review of clinical practice in a tertiary children's hospital using electronic health record linkage. Perceptions of service providers on available care for paediatric feeding disorder: A survey study. Paediatric oral and maxillofacial biopsies: A retrospective institutional archival study.
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