{"title":"A new dammarane-type triterpenoid saponin from the leaves of sour jujube.","authors":"Jin-Yan Tan, Pei Li, Si-Qi Yang, Jia-Ning Zhang, Yan-Gang Cheng","doi":"10.1080/14786419.2024.2427814","DOIUrl":null,"url":null,"abstract":"<p><p>A new dammarane-type triterpenoid saponin, suanzaoside A (<b>1</b>) along with one known analogue 3-<i>O</i>-[<i>α</i>-L-rhamnopyranosyl(1→2)-<i>α</i>-L-arabinopyranosyl-]-30-<i>O</i>-[<i>β</i>-D-glucopyranosyl-(1→2)-<i>β</i>-D-glucopyranosyl]-3<i>β</i>,25,30-trihydroxy-16-one-20<i>R</i>,24<i>R</i>-epoxydammarane (<b>2</b>), were isolated from the leaves of sour jujube. The structure of these isolated compounds was elucidated by HRESIMS, 1D and 2D NMR spectroscopy, and literature comparison. In addition, the anti-inflammatory activities were further tested in LPS-induced RAW264.7 macrophage.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"1-4"},"PeriodicalIF":1.9000,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2024.2427814","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
A new dammarane-type triterpenoid saponin, suanzaoside A (1) along with one known analogue 3-O-[α-L-rhamnopyranosyl(1→2)-α-L-arabinopyranosyl-]-30-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-3β,25,30-trihydroxy-16-one-20R,24R-epoxydammarane (2), were isolated from the leaves of sour jujube. The structure of these isolated compounds was elucidated by HRESIMS, 1D and 2D NMR spectroscopy, and literature comparison. In addition, the anti-inflammatory activities were further tested in LPS-induced RAW264.7 macrophage.
期刊介绍：
The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds.
The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal.
Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section.
All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.
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