Antiviral Effects and Mechanisms of Active Ingredients in Tea.

IF 4.2 2区 化学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecules Pub Date : 2024-11-04 DOI:10.3390/molecules29215218
Xinghai Zhang, Haonan Yu, Panjie Sun, Mengxin Huang, Bo Li
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Abstract

Viruses play a significant role in human health, as they can cause a wide range of diseases, from mild illnesses to severe and life-threatening conditions. Cellular and animal experiments have demonstrated that the functional components in tea, such as catechins, theaflavins, theanine, and caffeine, exhibit significant inhibitory effects on a diverse array of viruses, including influenza, rotavirus, hepatitis, HPV, and additional types. The inhibition mechanisms may involve blocking virus-host recognition, interfering with viral replication, enhancing host immune responses, and inhibiting viral enzyme activity. This article reviews the research progress on the antiviral effects of tea's functional components and their related mechanisms, hoping to contribute to future studies in this field.

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茶叶中活性成分的抗病毒作用和机制
病毒在人类健康中扮演着重要角色,因为它们可以引发多种疾病,从轻微的疾病到严重的危及生命的疾病。细胞和动物实验证明,茶叶中的功能成分,如儿茶素、茶黄素、茶氨酸和咖啡因,对多种病毒有显著的抑制作用,包括流感、轮状病毒、肝炎、人乳头瘤病毒和其他类型的病毒。抑制机制可能包括阻断病毒-宿主识别、干扰病毒复制、增强宿主免疫反应和抑制病毒酶活性。本文综述了茶叶功能成分的抗病毒作用及其相关机制的研究进展,希望对这一领域未来的研究有所帮助。
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来源期刊
Molecules
Molecules 化学-有机化学
CiteScore
7.40
自引率
8.70%
发文量
7524
审稿时长
1.4 months
期刊介绍: Molecules (ISSN 1420-3049, CODEN: MOLEFW) is an open access journal of synthetic organic chemistry and natural product chemistry. All articles are peer-reviewed and published continously upon acceptance. Molecules is published by MDPI, Basel, Switzerland. Our aim is to encourage chemists to publish as much as possible their experimental detail, particularly synthetic procedures and characterization information. There is no restriction on the length of the experimental section. In addition, availability of compound samples is published and considered as important information. Authors are encouraged to register or deposit their chemical samples through the non-profit international organization Molecular Diversity Preservation International (MDPI). Molecules has been launched in 1996 to preserve and exploit molecular diversity of both, chemical information and chemical substances.
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