K G Saliev, Yu G Sandler, K A Nikolskaya, T Yu Khaimenova, O V Knyazev
{"title":"[ISSUES OF ROUTING PATIENTS WITH AUTOIMMUNE HEPATITIS].","authors":"K G Saliev, Yu G Sandler, K A Nikolskaya, T Yu Khaimenova, O V Knyazev","doi":"10.32687/0869-866X-2024-32-s2-1160-1164","DOIUrl":null,"url":null,"abstract":"<p><p>Autoimmune hepatitis is a chronic, immune-mediated liver disease characterized by an increased level of immunoglobulins G and/or gamma globulins, the presence of autoantibodies and a typical histological picture. Diagnosis of autoimmune hepatitis causes difficulties due to various variants of the course, wide variability of the clinical picture, which leads to a large number of missed cases of the disease. Treatment of аutoimmune hepatitis is aimed at reducing the activity of an inadequate response of the immune system against cells of its own body and achieving complete remission of the disease. The timeliness of starting treatment is directly related to the prognosis of the disease. These features of the disease necessitate proper patient routing and shortening their path to specialists with knowledge and experience in managing this category of patients.</p>","PeriodicalId":35946,"journal":{"name":"Problemy sotsial''noi gigieny i istoriia meditsiny / NII sotsial''noi gigieny, ekonomiki i upravleniia zdravookhraneniem im. N.A. Semashko RAMN, AO ''Assotsiatsiia ''Meditsinskaia literatura''","volume":"32 Special 2","pages":"1160-1164"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Problemy sotsial''noi gigieny i istoriia meditsiny / NII sotsial''noi gigieny, ekonomiki i upravleniia zdravookhraneniem im. N.A. Semashko RAMN, AO ''Assotsiatsiia ''Meditsinskaia literatura''","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32687/0869-866X-2024-32-s2-1160-1164","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Autoimmune hepatitis is a chronic, immune-mediated liver disease characterized by an increased level of immunoglobulins G and/or gamma globulins, the presence of autoantibodies and a typical histological picture. Diagnosis of autoimmune hepatitis causes difficulties due to various variants of the course, wide variability of the clinical picture, which leads to a large number of missed cases of the disease. Treatment of аutoimmune hepatitis is aimed at reducing the activity of an inadequate response of the immune system against cells of its own body and achieving complete remission of the disease. The timeliness of starting treatment is directly related to the prognosis of the disease. These features of the disease necessitate proper patient routing and shortening their path to specialists with knowledge and experience in managing this category of patients.
自身免疫性肝炎是一种免疫介导的慢性肝病,其特点是免疫球蛋白 G 和/或γ 球蛋白水平升高、存在自身抗体以及典型的组织学表现。由于病程变化多端,临床表现千差万别,导致大量漏诊病例,给自身免疫性肝炎的诊断带来困难。治疗自身免疫性肝炎的目的是降低免疫系统对自身细胞不适当反应的活性,使疾病完全缓解。开始治疗的及时性直接关系到疾病的预后。由于该病的这些特点,有必要对患者进行适当的分流,缩短他们的就医路径,让他们能够找到在管理这类患者方面拥有知识和经验的专家。