Assessing Tramadol Hydrochloride as an Alternative to Lignocaine Hydrochloride in Dental Implant Procedures: A Randomized Trial.

Akshita N Parlawar, Bhushan P Mundada
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引用次数: 0

Abstract

Aim: To evaluate tramadol hydrochloride, an atypical opioid with potential analgesic properties, as a viable alternative to lignocaine hydrochloride in supraperiosteal anesthesia for dental implants.

Materials and methods: A split-mouth, double-blind, randomized controlled trial was conducted in patients requiring maxillary dental implants. Patients meeting inclusion criteria received either 5% tramadol hydrochloride with adrenaline or 2% lignocaine hydrochloride with adrenaline via supraperiosteal infiltration. Onset, duration of anesthesia, visual analog scale (VAS) pain scores, and adverse effects were recorded.

Results: Forty patients were included, with a mean age of 39.35 years, 62.5% male. No significant differences were observed in VAS pain scores between tramadol (2.08 ± 1.328) and lignocaine (2.05 ± 1.260) groups (p = 0.931). Onset of anesthesia showed no significant difference between the tramadol (128.00 ± 18.207 seconds) and lignocaine (128.30 ± 18.287 seconds) groups (p = 0.736). The duration of anesthesia was comparable between tramadol (59 ± 12.092 minutes) and lignocaine (59.90 ± 11.705 minutes) groups (p = 0.0736). Adverse effects included nausea in two tramadol and one lignocaine patient.

Conclusion: Tramadol hydrochloride demonstrated comparable local anesthetic efficacy to lignocaine hydrochloride in dental implant surgery Clinical significance: Both drugs provided effective pain control with similar onset and duration of anesthesia. Tramadol may offer an alternative for patients with lignocaine contraindications, although further studies are warranted to validate its safety and efficacy in dental procedures. How to cite this article: Parlawar AN, Mundada BP. Assessing Tramadol Hydrochloride as an Alternative to Lignocaine Hydrochloride in Dental Implant Procedures: A Randomized Trial. J Contemp Dent Pract 2024;25(7):639-644.

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评估盐酸曲马多在牙科植入手术中作为盐酸利格诺卡因的替代品:随机试验。
目的:评估盐酸曲马多--一种具有潜在镇痛特性的非典型阿片类药物--在牙槽骨骨膜上麻醉中作为盐酸木果卡因的可行替代品的效果:对需要进行上颌种植牙的患者进行了分口、双盲、随机对照试验。符合纳入标准的患者通过骨膜上浸润接受 5%盐酸曲马多加肾上腺素或 2%盐酸木质素加肾上腺素麻醉。记录了麻醉的开始时间、持续时间、视觉模拟量表(VAS)疼痛评分和不良反应:共纳入 40 名患者,平均年龄 39.35 岁,62.5% 为男性。曲马多组(2.08 ± 1.328)和木质素组(2.05 ± 1.260)的 VAS 疼痛评分无明显差异(P = 0.931)。麻醉起始时间在曲马多组(128.00 ± 18.207 秒)和木质素组(128.30 ± 18.287 秒)之间无显著差异(p = 0.736)。曲马多组(59±12.092 分钟)和木质素组(59.90±11.705 分钟)的麻醉持续时间相当(p = 0.0736)。不良反应包括两名曲马多患者和一名木质素卡因患者出现恶心:结论:在种植牙手术中,盐酸曲马多的局部麻醉效果与盐酸木质素相当:两种药物都能有效控制疼痛,起效时间和麻醉持续时间相似。曲马多可为有木质碱禁忌症的患者提供一种替代药物,但仍需进一步研究以验证其在牙科手术中的安全性和有效性。本文引用方式:Parlawar AN, Mundada BP.评估盐酸曲马多作为盐酸木酚卡因在牙科植入手术中的替代品:随机试验。J Contemp Dent Pract 2024;25(7):639-644.
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来源期刊
Journal of Contemporary Dental Practice
Journal of Contemporary Dental Practice Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
174
期刊介绍: The Journal of Contemporary Dental Practice (JCDP), is a peer-reviewed, open access MEDLINE indexed journal. The journal’s full text is available online at http://www.thejcdp.com. The journal allows free access (open access) to its contents. Articles with clinical relevance will be given preference for publication. The Journal publishes original research papers, review articles, rare and novel case reports, and clinical techniques. Manuscripts are invited from all specialties of dentistry i.e., conservative dentistry and endodontics, dentofacial orthopedics and orthodontics, oral medicine and radiology, oral pathology, oral surgery, orodental diseases, pediatric dentistry, implantology, periodontics, clinical aspects of public health dentistry, and prosthodontics.
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