Outcomes of Transarterial Embolization in Patients with Isolated Pelvic Fractures: A Japanese Nationwide Study Focused on Shock Status and Age

IF 2.6 3区 医学 Q2 PERIPHERAL VASCULAR DISEASE Journal of Vascular and Interventional Radiology Pub Date : 2025-02-01 DOI:10.1016/j.jvir.2024.10.032
Kosuke Otake MD, PhD , Takashi Tagami MD, MPH, PhD , Chie Tanaka MD, PhD , Yudai Yoshino MD , Akihiro Watanabe MD, PhD , Ami Shibata MD, PhD , Kentaro Kuwamoto MD , Junichi Inoue MD, PhD , Shoji Yokobori MD, PhD
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Abstract

Purpose

To investigate the effect of transarterial embolization (TAE) on the 30-day survival of patients with isolated pelvic fractures, focusing on the influence of shock status and age.

Materials and Methods

This retrospective cohort study used data from the Japan Trauma Data Bank (2004–2018). Patients with isolated pelvic fractures, defined by an Abbreviated Injury Scale score of ≥3, were included. Shock (shock index, ≥1) and nonshock (shock index, <1) were grouped. Inverse probability weighting using propensity scores was performed to adjust for the confounding factors. The primary outcome measure was the 30-day in-hospital mortality. The 30-day survival was compared by age groups: 0–19 years, 20–39 years, 40–59 years, 60–79 years, and ≥80 years.

Results

Of the 5,025 eligible patients, 866 presented with shock, and 4,159 served as the nonshock group. The propensity score analysis showed that there was no significant difference in survival between the TAE and non-TAE groups in patients without shock (TAE group vs non-TAE group, 92.4% vs 92.5%; risk difference, −0.05%; 95% CI, −0.5% to 0.4%). Conversely, for patients with shock, the TAE group had a significantly higher 30-day survival rate than the non-TAE group (83.0% vs 76.2%; risk difference, 6.7%; 95% CI, 5.1%–8.3%). Among the age groups, the risk difference was highest in the ≥80 years age group (78.5% vs 66.6%; risk difference, 11.9%; 95% CI, 7.7%–16.1%).

Conclusions

This nationwide study suggested that provision of TAE was associated with improved 30-day survival in patients with isolated pelvic fractures and shock, particularly for those aged ≥80 years.

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孤立性骨盆骨折患者经导管动脉栓塞术的疗效:以休克状态和年龄为重点的日本全国性研究。
目的:研究经导管动脉栓塞术(TAE)对孤立性骨盆骨折患者30天生存率的影响,重点关注休克状态和年龄的影响:这项回顾性队列研究使用了日本创伤数据库(2004-2018年)的数据。研究纳入了骨盆孤立性骨折患者,其定义为简易损伤量表评分≥3分。休克(休克指数≥1)和非休克(休克指数 结果:在符合条件的 5025 名患者中,有 866 人出现休克,4159 人属于非休克组。倾向得分分析显示,在无休克的患者中,TAE 组和非 TAE 组的存活率无明显差异(TAE 组:92.4%;非 TAE 组:92.4%):92.4%;风险差异-0.5%:92.5%;风险差异-0.05%,95%置信区间[CI]:-0.5%至0.4%)。相反,对于休克患者,TAE 组的 30 天存活率明显高于非 TAE 组(83.0% 对 76.2%;风险差异为 6.7%,95% 置信区间:5.1% 至 8.3%)。在各年龄组中,≥80 岁年龄组的风险差异最大(78.5% 对 66.6%,风险差异为 11.9%,95% CI:7.7% 至 16.1%):这项全国性研究表明,对孤立性骨盆骨折合并休克的患者,尤其是年龄≥80岁的患者,提供TAE可提高其30天生存率。
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来源期刊
CiteScore
4.30
自引率
10.30%
发文量
942
审稿时长
90 days
期刊介绍: JVIR, published continuously since 1990, is an international, monthly peer-reviewed interventional radiology journal. As the official journal of the Society of Interventional Radiology, JVIR is the peer-reviewed journal of choice for interventional radiologists, radiologists, cardiologists, vascular surgeons, neurosurgeons, and other clinicians who seek current and reliable information on every aspect of vascular and interventional radiology. Each issue of JVIR covers critical and cutting-edge medical minimally invasive, clinical, basic research, radiological, pathological, and socioeconomic issues of importance to the field.
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