{"title":"Outcomes of Transarterial Embolization in Patients with Isolated Pelvic Fractures: A Japanese Nationwide Study Focused on Shock Status and Age","authors":"Kosuke Otake MD, PhD , Takashi Tagami MD, MPH, PhD , Chie Tanaka MD, PhD , Yudai Yoshino MD , Akihiro Watanabe MD, PhD , Ami Shibata MD, PhD , Kentaro Kuwamoto MD , Junichi Inoue MD, PhD , Shoji Yokobori MD, PhD","doi":"10.1016/j.jvir.2024.10.032","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the effect of transarterial embolization (TAE) on the 30-day survival of patients with isolated pelvic fractures, focusing on the influence of shock status and age.</div></div><div><h3>Materials and Methods</h3><div>This retrospective cohort study used data from the Japan Trauma Data Bank (2004–2018). Patients with isolated pelvic fractures, defined by an Abbreviated Injury Scale score of ≥3, were included. Shock (shock index, ≥1) and nonshock (shock index, <1) were grouped. Inverse probability weighting using propensity scores was performed to adjust for the confounding factors. The primary outcome measure was the 30-day in-hospital mortality. The 30-day survival was compared by age groups: 0–19 years, 20–39 years, 40–59 years, 60–79 years, and ≥80 years.</div></div><div><h3>Results</h3><div>Of the 5,025 eligible patients, 866 presented with shock, and 4,159 served as the nonshock group. The propensity score analysis showed that there was no significant difference in survival between the TAE and non-TAE groups in patients without shock (TAE group vs non-TAE group, 92.4% vs 92.5%; risk difference, −0.05%; 95% CI, −0.5% to 0.4%). Conversely, for patients with shock, the TAE group had a significantly higher 30-day survival rate than the non-TAE group (83.0% vs 76.2%; risk difference, 6.7%; 95% CI, 5.1%–8.3%). Among the age groups, the risk difference was highest in the ≥80 years age group (78.5% vs 66.6%; risk difference, 11.9%; 95% CI, 7.7%–16.1%).</div></div><div><h3>Conclusions</h3><div>This nationwide study suggested that provision of TAE was associated with improved 30-day survival in patients with isolated pelvic fractures and shock, particularly for those aged ≥80 years.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 310-317.e1"},"PeriodicalIF":2.6000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Vascular and Interventional Radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1051044324006924","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose
To investigate the effect of transarterial embolization (TAE) on the 30-day survival of patients with isolated pelvic fractures, focusing on the influence of shock status and age.
Materials and Methods
This retrospective cohort study used data from the Japan Trauma Data Bank (2004–2018). Patients with isolated pelvic fractures, defined by an Abbreviated Injury Scale score of ≥3, were included. Shock (shock index, ≥1) and nonshock (shock index, <1) were grouped. Inverse probability weighting using propensity scores was performed to adjust for the confounding factors. The primary outcome measure was the 30-day in-hospital mortality. The 30-day survival was compared by age groups: 0–19 years, 20–39 years, 40–59 years, 60–79 years, and ≥80 years.
Results
Of the 5,025 eligible patients, 866 presented with shock, and 4,159 served as the nonshock group. The propensity score analysis showed that there was no significant difference in survival between the TAE and non-TAE groups in patients without shock (TAE group vs non-TAE group, 92.4% vs 92.5%; risk difference, −0.05%; 95% CI, −0.5% to 0.4%). Conversely, for patients with shock, the TAE group had a significantly higher 30-day survival rate than the non-TAE group (83.0% vs 76.2%; risk difference, 6.7%; 95% CI, 5.1%–8.3%). Among the age groups, the risk difference was highest in the ≥80 years age group (78.5% vs 66.6%; risk difference, 11.9%; 95% CI, 7.7%–16.1%).
Conclusions
This nationwide study suggested that provision of TAE was associated with improved 30-day survival in patients with isolated pelvic fractures and shock, particularly for those aged ≥80 years.
期刊介绍:
JVIR, published continuously since 1990, is an international, monthly peer-reviewed interventional radiology journal. As the official journal of the Society of Interventional Radiology, JVIR is the peer-reviewed journal of choice for interventional radiologists, radiologists, cardiologists, vascular surgeons, neurosurgeons, and other clinicians who seek current and reliable information on every aspect of vascular and interventional radiology. Each issue of JVIR covers critical and cutting-edge medical minimally invasive, clinical, basic research, radiological, pathological, and socioeconomic issues of importance to the field.