New strategies for lung cancer diagnosis and treatment: applications and advances in nanotechnology.

IF 9.5 2区 医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL Biomarker Research Pub Date : 2024-11-13 DOI:10.1186/s40364-024-00686-7
Jiaqi Feng, Pengpeng Zhang, Dingli Wang, Yuting Li, Jiaxiong Tan
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Abstract

Lung cancer leads in causing cancer-related mortality worldwide, continually posing a significant threat to human health. Current imaging diagnostic techniques, while offering non-invasive detection, suffer from issues such as insufficient sensitivity and the risks associated with radiation exposure. Pathological diagnosis, the gold standard for confirmation, also faces challenges like invasiveness and high costs. In treatment, surgery, radiotherapy, and chemotherapy are the main modalities, each encountering challenges related to precision, environmental adaptability, and side effects. Nanotechnology's advancement provides new solutions for the diagnosis and treatment of lung cancer, promising to enhance diagnostic accuracy and reduce side effects during treatment. This article introduces the main types of nanomaterials used in the field of lung cancer, offering a comprehensive overview of current research on the application of nanotechnology in early screening, diagnosis, treatment, and monitoring of lung cancer, and summarizing ongoing clinical research findings.

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肺癌诊断和治疗的新策略:纳米技术的应用和进展。
肺癌是导致全球癌症相关死亡的主要原因,持续对人类健康构成重大威胁。目前的成像诊断技术虽然可以提供无创检测,但存在灵敏度不足和辐射风险等问题。病理诊断作为确诊的黄金标准,也面临着侵入性和高成本等挑战。在治疗方面,手术、放疗和化疗是主要方式,但每种方式都面临着精确性、环境适应性和副作用等挑战。纳米技术的发展为肺癌的诊断和治疗提供了新的解决方案,有望提高诊断的准确性,减少治疗过程中的副作用。本文介绍了肺癌领域使用的主要纳米材料类型,全面概述了当前纳米技术在肺癌早期筛查、诊断、治疗和监测中的应用研究,并总结了正在进行的临床研究成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomarker Research
Biomarker Research Biochemistry, Genetics and Molecular Biology-Molecular Medicine
CiteScore
15.80
自引率
1.80%
发文量
80
审稿时长
10 weeks
期刊介绍: Biomarker Research, an open-access, peer-reviewed journal, covers all aspects of biomarker investigation. It seeks to publish original discoveries, novel concepts, commentaries, and reviews across various biomedical disciplines. The field of biomarker research has progressed significantly with the rise of personalized medicine and individual health. Biomarkers play a crucial role in drug discovery and development, as well as in disease diagnosis, treatment, prognosis, and prevention, particularly in the genome era.
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