The influence of anxiety on exploration: A review of computational modeling studies.

Abstract

Exploratory behaviors can serve an adaptive role within novel or changing environments. Namely, they facilitate information gain, allowing an organism to maintain accurate beliefs about the environment and select actions that better maximize reward. However, finding the optimal balance between exploration and reward-seeking behavior - the so-called explore-exploit dilemma - can be challenging, as it requires sensitivity to one's own uncertainty and to the predictability of one's surroundings. Given the close relationship between uncertainty and anxiety, a body of work has now also emerged identifying associated effects on exploration. In particular, the field of computational psychiatry has begun to use cognitive computational models to characterize how anxiety may modulate underlying information processing mechanisms, such as estimation of uncertainty and the value of information, and how this might contribute to psychopathology. Here, we review computational modeling studies investigating how exploration is influenced by anxiety. While some apparent inconsistencies remain to be resolved, studies using reinforcement learning tasks suggest that directed (but not random) forms of exploration may be elevated by trait and/or cognitive anxiety, but reduced by state and/or somatic anxiety. Anxiety is also consistently associated with less exploration in foraging tasks. Some differences in exploration may further stem from how anxiety modulates changes in uncertainty over time (learning rates). Jointly, these results highlight important directions for future work in refining choice of tasks and anxiety measures and maintaining consistent methodology across studies.