In vivo optical tissue clearing using light-absorbing dyes

IF 5.9 3区 农林科学 Q1 VETERINARY SCIENCES Lab Animal Pub Date : 2024-11-15 DOI:10.1038/s41684-024-01472-6
Maria Victoria Gómez-Gaviro, Vicente Llorente
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Abstract

Optical tissue clearing allows high-resolution microscopy imaging of biological samples while retaining critical three-dimensional and structural information for research and diagnosis. Most methods can only be performed ex vivo on fixed tissues, but a new study claims to have found a technique that can render live tissue transparent.

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使用光吸收染料进行体内光学组织清除
光学组织清除技术可对生物样本进行高分辨率显微成像,同时保留研究和诊断所需的关键三维和结构信息。大多数方法只能在固定组织的体外进行,但一项新的研究声称找到了一种能使活体组织透明的技术。
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来源期刊
Lab Animal
Lab Animal 农林科学-兽医学
CiteScore
0.60
自引率
2.90%
发文量
181
审稿时长
>36 weeks
期刊介绍: LabAnimal is a Nature Research journal dedicated to in vivo science and technology that improves our basic understanding and use of model organisms of human health and disease. In addition to basic research, methods and technologies, LabAnimal also covers important news, business and regulatory matters that impact the development and application of model organisms for preclinical research. LabAnimal's focus is on innovative in vivo methods, research and technology covering a wide range of model organisms. Our broad scope ensures that the work we publish reaches the widest possible audience. LabAnimal provides a rigorous and fair peer review of manuscripts, high standards for copyediting and production, and efficient publication.
期刊最新文献
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