Fe₃O₄@SiO₂@[Aminoglycol][Formate] as a new superparamagnetic nanocatalyst and [Aminoglycol][Formate] as a novel ionic liquid catalyst for preparation of new dimethyldihydropyrimido[4,5-b]quinolone derivatives.

IF 3.9 2区化学 Q2 CHEMISTRY, APPLIED Molecular Diversity Pub Date : 2024-11-15 DOI:10.1007/s11030-024-11013-5

Fatemeh Bani Asadi, Farhad Shirzaei, Hamid Reza Shaterian

引用次数: 0

Abstract

Efficient synthesis of novel dimethyldihydropyrimido[4,5-b]quinolones via three-component condensation of barbituric acid, arylaldehydes, and 3,4-dimethylaniline catalyzed by Fe₃O₄@SiO₂@[Aminoglycol][Formate] as a new superparamagnetic nanocatalyst and [Aminoglycol][Formate] as a novel ionic liquid catalyst was described. The new heterogeneous nanocatalyst was characterized by FE-SEM, XRD, FT-IR, TGA-DTG, and VSM techniques. The new ionic liquid was characterized by ¹³CNMR, ¹HNMR, and FT-IR techniques. The present work has advantages, such as excellent yields, short reaction times, environmentally friendly protocol, easy separation, and purification of products. The catalysts kept its catalytic properties after even five recoverability and reusability.

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Fe3O4@SiO2@[氨基乙二醇][甲酸盐]作为一种新型超顺磁性纳米催化剂和[氨基乙二醇][甲酸盐]作为一种新型离子液体催化剂制备新的二甲基二氢嘧啶并[4,5-b]喹啉酮衍生物。

介绍了在新型超顺磁性纳米催化剂 Fe3O4@SiO2@[Aminoglycol][Formate] 和新型离子液体催化剂 [Aminoglycol][Fateate]催化下，通过巴比妥酸、芳基醛和 3,4 二甲基苯胺的三组分缩合，高效合成新型二甲基二氢嘧啶并[4,5-b]喹诺酮类化合物。该新型异质纳米催化剂通过 FE-SEM、XRD、FT-IR、TGA-DTG 和 VSM 技术进行了表征。利用 13CNMR、1HNMR 和傅立叶变换红外技术对新型离子液体进行了表征。本研究成果具有产率高、反应时间短、方案环保、易于分离和纯化产品等优点。催化剂在五次回收和重复使用后仍能保持其催化特性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Diversity 化学-化学综合

CiteScore

7.30

自引率

7.90%

发文量

219

审稿时长

2.7 months

期刊介绍： Molecular Diversity is a new publication forum for the rapid publication of refereed papers dedicated to describing the development, application and theory of molecular diversity and combinatorial chemistry in basic and applied research and drug discovery. The journal publishes both short and full papers, perspectives, news and reviews dealing with all aspects of the generation of molecular diversity, application of diversity for screening against alternative targets of all types (biological, biophysical, technological), analysis of results obtained and their application in various scientific disciplines/approaches including: combinatorial chemistry and parallel synthesis; small molecule libraries; microwave synthesis; flow synthesis; fluorous synthesis; diversity oriented synthesis (DOS); nanoreactors; click chemistry; multiplex technologies; fragment- and ligand-based design; structure/function/SAR; computational chemistry and molecular design; chemoinformatics; screening techniques and screening interfaces; analytical and purification methods; robotics, automation and miniaturization; targeted libraries; display libraries; peptides and peptoids; proteins; oligonucleotides; carbohydrates; natural diversity; new methods of library formulation and deconvolution; directed evolution, origin of life and recombination; search techniques, landscapes, random chemistry and more;

Fe3O4@SiO2@[Aminoglycol][Formate] as a new superparamagnetic nanocatalyst and [Aminoglycol][Formate] as a novel ionic liquid catalyst for preparation of new dimethyldihydropyrimido[4,5-b]quinolone derivatives.

Abstract

Fe₃O₄@SiO₂@[Aminoglycol][Formate] as a new superparamagnetic nanocatalyst and [Aminoglycol][Formate] as a novel ionic liquid catalyst for preparation of new dimethyldihydropyrimido[4,5-b]quinolone derivatives.