Evaluating Laser-Based Microfabrication in Microfluidics: An Experimental and Computational Trial

IF 3.4 3区 材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY Advanced Engineering Materials Pub Date : 2024-10-04 DOI:10.1002/adem.202401105
Alice Betti, Claudio Ongaro, Barbara Zardin, Jessika Bertacchini, Nadia Tagliaferri, Vincenzina Siciliani, Leonardo Orazi, Massimo Borghi
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Abstract

The aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser-etched glass and pre-cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine-tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis.

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评估微流体中基于激光的微细加工:实验与计算试验
这项研究的目的是验证一种新的微流体设备原型制作方法,该方法可与广泛使用的聚二甲基硅氧烷软光刻法相媲美。这种替代方法使用激光蚀刻玻璃和预固化硅胶作为主要材料。我们选择了一种双重方法进行验证,测试科学文献中众所周知的混合装置原型。具体来说,重点是评估流经该装置的两种流体的混合效率(ME)。在对制造过程进行微调后,对 ME 进行了实验评估,并将结果与三维计算流体动力学分析进行了比较。
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来源期刊
Advanced Engineering Materials
Advanced Engineering Materials 工程技术-材料科学:综合
CiteScore
5.70
自引率
5.60%
发文量
544
审稿时长
1.7 months
期刊介绍: Advanced Engineering Materials is the membership journal of three leading European Materials Societies - German Materials Society/DGM, - French Materials Society/SF2M, - Swiss Materials Federation/SVMT.
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