Comparison of responders and nonresponders with knee osteoarthritis after transcranial direct current stimulation.

IF 1.4 Q4 CLINICAL NEUROLOGY Pain management Pub Date : 2024-09-01 Epub Date: 2024-11-16 DOI:10.1080/17581869.2024.2429943

Juyoung Park, Heling Tong, Yixin Kang, Hongyu Miao, Lifeng Lin, Rina S Fox, Ilknur Telkes, Geraldine Martorella, Hyochol Ahn

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Abstract

Aim: The study compared responders and nonresponders to transcranial direct current stimulation (tDCS) regarding clinical pain outcomes in knee osteoarthritis (OA) patients.

Patients and methods/materials: Sixty participants received home-based active tDCS, and clinical pain outcomes were compared between responders and nonresponders.

Results: Latent class growth analyses classified 41 participants as responders and 19 as nonresponders. Responders showed significantly greater decreases in pain intensity from baseline to post intervention than nonresponders (p < .001). Participants with higher BMI (p = .02) and weight (p = .005) were more likely to respond, while no significant sociodemographic differences were found.

Conclusions: Identifying characteristics of nonresponsive tDCS subgroups can tailor treatments for each group.

Clinical trial registration: www.clinicaltrials.gov identifier is NCT04016272.

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经颅直流电刺激后膝关节骨关节炎有反应者与无反应者的比较。

目的：该研究比较了经颅直流电刺激（tDCS）对膝关节骨性关节炎（OA）患者的临床疼痛结果有反应者和无反应者：60名参与者接受了基于家庭的主动tDCS治疗，并对有反应者和无反应者的临床疼痛结果进行了比较：结果：潜类增长分析将 41 名参与者归为应答者，19 名归为非应答者。有反应者从基线到干预后疼痛强度的下降幅度明显大于无反应者（p p = .02），体重（p = .005）更有可能有反应，而社会人口学方面没有发现明显差异：临床试验注册：www.clinicaltrials.gov 识别码为 NCT04016272。

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来源期刊

Pain management CLINICAL NEUROLOGY-

CiteScore

2.90

自引率

5.90%

发文量