Role and applications of ¹⁸F-FDG PET/CT in the assessment of osteoarticular infection and inflammation - Part I.

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-11-15 DOI:10.1016/j.remnie.2024.500073

E Noriega-Álvarez, B Rodríguez Alfonso, J J Rosales Castillo, A Moreno Ballesteros, E López Rodríguez, S Sanz Viedma, M Del P Orduña Diez, L Domínguez Gadea

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Abstract

¹⁸F-FDG PET/CT has been positioned over time as a useful tool in the evaluation of osteoarticular infections, overcoming conventional explorations like MRI or bone scintigraphy in some indications. Its ability to provide functional and anatomical images simultaneously and its excellent resolution contributes to a more precise and personalised approach in the treatment of osteoarticular diseases such as spondylodiscitis. In addition, it has proven valuable in patients with suspected infection that is complex to diagnose or treat, improving detection in subclinical stages. However, some limitations have been identified, such as difficulty in the differential diagnosis of infection vs. inflammation (as in diabetic foot) or in the interpretation of patients with osteosynthesis materials. In this manuscript, we present a brief review providing general and practical information about the role of ¹⁸F-FDG PET/CT in infectious osteoarticular pathology, while part 2 discusses the role of ¹⁸F-FDG PET/CT in osteoarticular inflammation.

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18F-FDG PET/CT 在骨关节感染和炎症评估中的作用和应用 - 第一部分。

随着时间的推移，18F-FDG PET/CT 已被定位为评估骨关节感染的有用工具，在某些适应症中可取代核磁共振成像或骨闪烁成像等传统检查方法。它能同时提供功能和解剖图像，分辨率极高，有助于在治疗脊柱盘炎等骨关节疾病时采用更精确和个性化的方法。此外，对于诊断或治疗复杂的疑似感染患者，该技术也被证明非常有价值，可改善亚临床阶段的检测。然而，我们也发现了一些局限性，例如在鉴别诊断感染与炎症（如糖尿病足）或解释使用骨合成材料的患者方面存在困难。在本手稿中，我们将简要回顾 18F-FDG PET/CT 在感染性骨关节病理学中的作用，并提供相关实用信息；第二部分将讨论 18F-FDG PET/CT 在骨关节炎症中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revista espanola de medicina nuclear e imagen molecular

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