Revista espanola de medicina nuclear e imagen molecular最新文献

{"title":"Peritoneal carcinomatosis with PSMA-PET/TC (¹⁸F-DCFPyL).","authors":"G Molina Mendoza, F Pena Pardo, M Contreras Ameduri, B Gonzalez García, V M Poblete García","doi":"10.1016/j.remnie.2026.500311","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500311","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500311"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pheochromocytoma with sympathetic hyperactivity: a diagnostic challenge.","authors":"D Tercero Garrido, A S De Agrela Serrao, M V Guiote Moreno, J Fernández Fernández, M Nicolas Aguado, J A Vallejo Casas","doi":"10.1016/j.remnie.2026.500312","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500312","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500312"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147494388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Impact of 18F-PSMA-1007 PET/MRI in staging Intermediate/ High-Risk Prostate Cancer Patients: Imaging Biomarkers and Radiomic Analysis Associated with Tumor Aggressiveness.","authors":"J R Garcia, L Pinilla, A Compte, N Garrido, L L Mont-Castro, S Ruiz, J Garcia Magro, J M Santabárbara, D Tovar, S Mourelo, M Soria, E Riera","doi":"10.1016/j.remnie.2026.500309","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500309","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of initial staging in prostate cancer patients using 18F-PSMA PET/MR and to analyze the prognostic value of pre-treatment PET/MRI imaging biomarkers.</p><p><strong>Methods: </strong>Prospective study of 50 consecutive patients diagnosed with intermediate/high-risk prostate cancer. Simultaneous acquisition on PET/MR (SIGNA GE) 1 hour after intravenous administration of 370 ± 10% MBq of 18F-PSMA-1007: - Prostate (20 min): PET emission + mpMRI sequences: DIXON, T1, T2, DWI, DCE. - Whole-body (30 min): PET emission + MR sequences: DIXON, T1, T2, DWI, STIR. Consensus between nuclear medicine physician and radiologist for T, nodal, and metastatic staging. Visual interpretation. Treatment selection by multidisciplinary tumor board. SUV and ADC values were calculated. Pearson correlation analysis was performed. Radiomic analysis included extraction of 93 features: first-order and texture-based. Significant differentiation was assessed using ANOVA between two prognostic groups: (1) TxN0M0 or TxN1M0; (2) TxN1M1a or M1b.</p><p><strong>Results: </strong>PET/MRI enabled comprehensive staging in a single session, classifying 28% of patients as T3b and detecting extraprostatic disease in 44% (28% oligometastatic, 16% polymetastatic). PET/MRI concordance for extracapsular extension and seminal vesicle infiltration was high in T3b (85.7%) but markedly lower in T3a (25%). SUVmax/ADC correlation was inverse and significant (p < 0.05). Texture features showed superior discriminative ability compared to conventional parameters, achieving an AUC of 0.79 for differentiating advanced T stages. Following PET/MR, 66% of patients underwent radical prostatectomy (with targeted lymphadenectomy in N1), 18% received image-guided radiotherapy, and 16% systemic therapy, without performing surgery in cases with extracapsular extension or metastatic disease.</p><p><strong>Conclusion: </strong>PET/MRI with [18F]F-PSMA-1007 is a feasible and effective technique for initial staging of intermediate/high-risk prostate cancer, acting as a comprehensive \"one-stop\" diagnostic procedure. Its high sensitivity for nodal and bone disease, combined with integration of radiomic biomarkers, provides prognostic value and enables optimization of personalized therapeutic decisions.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500309"},"PeriodicalIF":0.0,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal and Hematologic Toxicity Profile of [177] Lu-labeled PSMA-targeted radioligand-therapy (¹⁷⁷Lu-PSMA-RLT): A Retrospective Cohort Study.","authors":"Merve Yalçınkaya, Fadime Demir, Seyhan Karaçavuş, Mustafa Demir","doi":"10.1016/j.remnie.2026.500306","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500306","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to retrospectively evaluate the renal and hematologic toxicity profile of ¹⁷⁷Lu-PSMA-RLT in patients with metastatic castration-resistant prostate cancer.</p><p><strong>Methods: </strong>Renal function (GFR, BUN, and creatinine) and hematological parameters (hemoglobin, leukocyte, platelet) before and after treatment were examined in 41 patients who received ¹⁷⁷Lu-PSMA-RLT at our clinic, and changes along with toxicity grades were determined. Additionally, pre-treatment PSMA PET/CT findings and other demographic and clinical data were assessed.</p><p><strong>Results: </strong>In terms of renal toxicity, G0-G1 level toxicity was observed in 97.6% of cases, while G2 toxicity was observed in only one patient. This patient already had a low GFR before treatment and experienced only a 3-unit decrease. Regarding hematological toxicity, the rates of G3-4 toxicity were as follows: leukocytes 7.3%, hemoglobin 9.8%, platelets 7.3%.</p><p><strong>Conclusion: </strong>No clinically significant nephrotoxicity was observed with ¹⁷⁷Lu-PSMA-RLT. Hematologic toxicity is significant but manageable, and severe side effects are rare and within predictable limits.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500306"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸F-FDG PET/CT in Agressive Pericardial Mesothelioma.","authors":"Busra Bozca, Nazli Altun Yologlu, Ozlem Ozmen","doi":"10.1016/j.remnie.2026.500307","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500307","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500307"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic pattern of Huntington´s disease on PET-TC and other imaging tests in Nuclear Medicine.","authors":"R González Couto, A Sanfiel Delgado, M R Malo de Molina Zamora, S Cifuentes Díaz, A E Jiménez Medina, M C Isla Gallego","doi":"10.1016/j.remnie.2026.500310","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500310","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500310"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exceptional craniofacial uptake pattern on bone scintigraphy.","authors":"S de la Torre Fernández, B Aradas Cabado, A K Minguillan Van Kapel, D Castro Cardenas, A E Seva Delgado, C M Hernández Heredia","doi":"10.1016/j.remnie.2026.500305","DOIUrl":"https://doi.org/10.1016/j.remnie.2026.500305","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500305"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147483212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective sentinel lymph node biopsy in a tumor on axillary ectopic breast tissue","authors":"R. González Couto,&nbsp;C.M. Carballo Menayo,&nbsp;A. Sanfiel Delgado,&nbsp;F.J. González Hernández,&nbsp;S. Cifuentes Díaz,&nbsp;M.C. Isla Gallego","doi":"10.1016/j.remnie.2025.500207","DOIUrl":"10.1016/j.remnie.2025.500207","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 2","pages":"Article 500207"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of extremely rare testicular cancer metastasis to the duodenum with 18F-FDG PET/CT","authors":"Muhammet Fatih Beytur ,&nbsp;Enver Yarıkkaya ,&nbsp;Sevim Baykal Koca ,&nbsp;Göksel Alçın ,&nbsp;Elife Akgün ,&nbsp;Erkan Erkan ,&nbsp;Esra Arslan","doi":"10.1016/j.remnie.2025.500230","DOIUrl":"10.1016/j.remnie.2025.500230","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 2","pages":"Article 500230"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145093295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG PET/CT in pulmonary Castleman's disease","authors":"H.Y. Zhang ,&nbsp;X. Yang","doi":"10.1016/j.remnie.2025.500209","DOIUrl":"10.1016/j.remnie.2025.500209","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 2","pages":"Article 500209"},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}