Affordable ultra-widefield smartphone PedCam for comprehensive pediatric retinal examination.

IF 2.9 2区医学 Q2 BIOCHEMICAL RESEARCH METHODS Biomedical optics express Pub Date : 2024-10-02 eCollection Date: 2024-11-01 DOI:10.1364/BOE.537633

Alfa Rossi, Devrim Toslak, Muhammet Kazim Erol, Mojtaba Rahimi, Taeyoon Son, R V Paul Chan, Xincheng Yao

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Abstract

Widefield fundus photography is critical for the detection, documentation, and management of pediatric eye diseases. Existing clinical pediatric fundus cameras offer a limited field of view (FOV) and suboptimal image contrast, hindering comprehensive peripheral retina examination. Additionally, the high cost and lack of portability of commercial devices restrict their use in resource-limited settings. We introduce a cost-effective smartphone-based pediatric camera (PedCam) that provides a 180° eye angle (126° visual angle) snapshot FOV. Utilizing trans-pars planar illumination, the device enables nonmydriatic imaging by allocating the pupil exclusively for imaging, eliminating the need for pharmacological pupillary dilation. By adjusting the optical axis of the PedCam relative to the ocular axis, the effective FOV can be expanded up to 240° eye angle (180° visual angle), enabling complete retinal evaluation. This innovative smartphone PedCam represents a significant advancement in affordable telemedicine for the screening, monitoring, and management of retinopathy of prematurity and other pediatric eye conditions.

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经济实惠的超宽视场智能手机 PedCam，用于全面的儿科视网膜检查。

宽视野眼底摄影对于儿科眼病的检测、记录和管理至关重要。现有的临床儿科眼底照相机视野（FOV）有限，图像对比度不理想，妨碍了全面的周边视网膜检查。此外，商业设备的高成本和缺乏便携性也限制了它们在资源有限环境中的使用。我们推出了一款基于智能手机的高性价比儿科相机（PedCam），它能提供 180°视角（126°视角）的快照视场角。该设备利用跨柱平面照明，通过将瞳孔专门用于成像，实现了非眼球成像，无需药物性瞳孔扩张。通过调整 PedCam 相对于眼轴的光轴，有效视场角可扩大至 240°（180° 视角），从而实现完整的视网膜评估。这款创新型智能手机 PedCam 标志着经济型远程医疗在筛查、监测和管理早产儿视网膜病变和其他儿科眼病方面取得了重大进展。

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来源期刊

Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS

CiteScore

6.80

自引率

11.80%

发文量

633

审稿时长

1 months

期刊介绍： The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.