Measurement of ocular aberration in noise based on deep learning with a Shack-Hartmann wavefront sensor.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS Biomedical optics express Pub Date : 2024-10-25 eCollection Date: 2024-11-01 DOI:10.1364/BOE.541483
Haobo Zhang, Yanrong Yang, Zitao Zhang, Chun Yin, Shengqian Wang, Kai Wei, Hao Chen, Junlei Zhao
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Abstract

Shack-Hartmann-based wavefront sensing combined with deep learning, due to its fast, accurate, and large dynamic range, has been widely studied in many fields including ocular aberration measurement. Problems such as noise and corneal reflection affect the accuracy of detection in practical measuring ocular aberration systems. This paper establishes a framework comprising of a noise-added model, Hartmannograms with corneal reflections and the corneal reflection elimination algorithm. Therefore, a more realistic data set is obtained, enabling the convolutional neural network to learn more comprehensive features and carry out real machine verification. The results show that the proposed method has excellent measurement accuracy. The root mean square error (RMSE) of the residual wavefront is 0.00924 ± 0.0207λ (mean ± standard deviation) in simulation and 0.0496 ± 0.0156λ in a real machine. Compared with other methods, this network combined with the proposed corneal reflection elimination algorithm is more accurate, speedier, and more widely applicable in the noise and corneal reflection situations, making it a promising tool for ocular aberration measurement.

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利用 Shack-Hartmann 波前传感器,基于深度学习测量噪声中的眼球像差。
基于 Shack-Hartmann 的波前传感技术与深度学习相结合,具有快速、准确和动态范围大的特点,已在包括眼球像差测量在内的许多领域得到广泛研究。在实际的眼球像差测量系统中,噪声和角膜反射等问题影响着检测的准确性。本文建立了一个框架,由添加噪声的模型、带有角膜反射的哈特曼图和角膜反射消除算法组成。因此,可以获得更真实的数据集,使卷积神经网络能够学习到更全面的特征,并进行真正的机器验证。结果表明,所提出的方法具有出色的测量精度。残余波前的均方根误差(RMSE)在仿真中为 0.00924 ± 0.0207λ(均值 ± 标准差),在真机上为 0.0496 ± 0.0156λ。与其他方法相比,该网络与所提出的角膜反射消除算法相结合,在噪声和角膜反射情况下更准确、更快速、适用范围更广,是一种很有前途的眼像差测量工具。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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