Torus palatinus osteonecrosis: A hitherto unreported complication of long-term Denosumab use

Q4 Medicine Radiology Case Reports Pub Date : 2024-11-14 DOI:10.1016/j.radcr.2024.10.082
Kendal L. Weger MD, Maani M. Archang MD, Ying-Chun Lo MD, Linda X. Yin MD, Michael F. Armstrong MD, Julie B. Guerin MD, Ian T. Mark MD, John C. Benson MD
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Abstract

Torus palatinus is an osseus exostosis found in the midline of the hard palate. It is a relatively common condition and is benign in nearly all cases. However, complications such as airway obstruction, sleep apnea, and swallowing difficulties do exist. One of the more serious complications is osteonecrosis. Osteonecrosis of tori has scantly been reported in the literature. Reported risk factors include bisphosphonate use, trauma, and anticoagulation. Here, we present a case of torus palatinus osteonecrosis in the setting of Denosumab use, a monoclonal antibody for the treatment of osteoporosis. This case brings awareness to a rare, but important, potential complication of long-term use of that medication.
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腭骨坏死:迄今未报告的长期使用地诺单抗的并发症
腭骨托是一种位于硬腭中线的骨外突。这是一种比较常见的疾病,几乎所有病例都是良性的。但也存在气道阻塞、睡眠呼吸暂停和吞咽困难等并发症。其中比较严重的并发症是骨坏死。文献中很少有鸟嘴骨坏死的报道。已报道的危险因素包括使用双膦酸盐、创伤和抗凝。在此,我们介绍了一例在使用地诺单抗(一种用于治疗骨质疏松症的单克隆抗体)的情况下发生的腭突骨坏死病例。该病例使人们认识到长期使用该药物可能导致的一种罕见但重要的并发症。
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来源期刊
Radiology Case Reports
Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
1.10
自引率
0.00%
发文量
1074
审稿时长
30 days
期刊介绍: The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.
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