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Aortoiliac and superior mesenteric artery narrowing and calcification in Singleton Merten syndrome Singleton Merten综合征的髂主动脉和肠系膜上动脉狭窄和钙化
Q4 Medicine Pub Date : 2025-12-20 DOI: 10.1016/j.radcr.2025.11.037
Hajra Arshad MD, Elliot K. Fishman MD
Singleton Merten Syndrome (SMS) is a rare autosomal dominant disorder caused by IFIH1 or DDX58 mutations, characterized by chronic inflammation leading to vascular calcifications, valvular disease, musculoskeletal abnormalities, dental dysplasia, skin findings like psoriasis and glaucoma. We report an 8-year-old boy with a DDX58 mutation associated SMS who presented with difficulty walking and ankle pain, found to have extensive aortoiliac and mesenteric artery narrowing. Advanced imaging with computed tomography (CT) and cinematic rendering provided detailed vascular mapping, underscoring the importance of radiologic evaluation in detecting and evaluating the extent of vascular involvement in SMS.
单例默顿综合征(SMS)是一种罕见的常染色体显性遗传病,由IFIH1或DDX58突变引起,其特征是慢性炎症导致血管钙化、瓣膜疾病、肌肉骨骼异常、牙齿发育不良、皮肤表现如牛皮癣和青光眼。我们报告了一个8岁的男孩,DDX58突变相关的SMS,表现为行走困难和踝关节疼痛,发现有广泛的主动脉髂动脉和肠系膜动脉狭窄。计算机断层扫描(CT)和电影渲染的先进成像提供了详细的血管测绘,强调了放射学评估在检测和评估血管受累程度方面的重要性。
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引用次数: 0
A case of endovascular treatment for pseudoaneurysm of the popliteal artery that developed 3 months after stenting 血管内治疗腘动脉假性动脉瘤3个月后发生
Q4 Medicine Pub Date : 2025-12-20 DOI: 10.1016/j.radcr.2025.11.086
Takahiro Otsuka MD , Hideki Wada MD, PhD , Jun Shitara MD, PhD , Hirohisa Endo MD, PhD , Manabu Ogita MD, PhD , Satoru Suwa MD , Tohru Minamino MD, PhD
Pseudoaneurysms in lower limb arteries are rare, but can occur after endovascular procedures. We report the case of an 80-year-old man with a chronic limb-threatening ischemia who developed pseudoaneurysm at the site of a stent placed in the left popliteal artery 3 months earlier. Because of the severe pain and risk of aneurysm rupture, intervention was considered necessary. Considering the frailty of the patient, surgical treatment would have likely been difficult and endovascular treatment was therefore planned. A stent graft was placed, blocking blood flow to the pseudoaneurysm. This case demonstrates the effectiveness of stent grafts in managing post-endovascular pseudoaneurysm.
下肢动脉假性动脉瘤是罕见的,但可以在血管内手术后发生。我们报告一例80岁男性慢性肢体缺血患者,3个月前在左腘动脉支架处出现假性动脉瘤。由于严重的疼痛和动脉瘤破裂的风险,干预是必要的。考虑到患者体弱多病,手术治疗可能会很困难,因此计划进行血管内治疗。植入支架,阻断血液流向假性动脉瘤。本病例证明了支架移植治疗血管内假性动脉瘤的有效性。
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引用次数: 0
Wernicke’s encephalopathy after emergency cholecystectomy and hepatic arterial embolization: A radiological and critical care challenge 急诊胆囊切除术和肝动脉栓塞后的韦尼克脑病:放射学和重症监护的挑战
Q4 Medicine Pub Date : 2025-12-20 DOI: 10.1016/j.radcr.2025.11.072
Manuela Montatore MD , Antonio Zagaria MD , Federica Masino MD , Marina Balbino MD , Giuseppe Guglielmi MD
Wernicke’s encephalopathy (WE) is an acute neuro-metabolic disorder caused by thiamine deficiency. In postoperative and critically ill patients, subtle neurological signs are often masked by sedation, delaying diagnosis. A 59-year-old woman underwent emergent cholecystectomy for acute cholecystitis complicated by multiple bilomas. Postoperative hemorrhage required superselective hepatic artery embolization. After initial stabilization and discharge, she was readmitted with respiratory failure and reduced consciousness, requiring intubation and mechanical ventilation. Despite cessation of sedation, she remained in prolonged coma. MRI revealed symmetrical thalamic, mammillary body, and periaqueductal lesions consistent with WE. Low serum thiamine levels confirmed the diagnosis. High-dose intravenous thiamine led to progressive neurological improvement. WE in nonalcoholic postoperative ICU patients is frequently underrecognized due to overlapping metabolic disturbances, insufficient nutritional intake, and sedation masking neurological signs. MRI is crucial for early diagnosis. Multidisciplinary coordination between intensivists, radiologists, anesthesiologists, and nutritionists is essential for timely recognition and treatment. This case highlights the importance of vigilant nutritional assessment, early neuroimaging, and empiric thiamine administration in postoperative ICU patients with unexplained persistent coma to prevent irreversible neurological damage.
韦尼克脑病(WE)是一种由硫胺素缺乏引起的急性神经代谢疾病。在术后和危重病人,微妙的神经症状往往被镇静掩盖,延误诊断。一位59岁的女性因急性胆囊炎并发多发性胆囊瘤而接受紧急胆囊切除术。术后出血需要超选择性肝动脉栓塞。初步稳定出院后,患者因呼吸衰竭和意识下降再次入院,需要插管和机械通气。尽管停止了镇定剂,她仍处于长时间昏迷状态。MRI显示对称的丘脑、乳头体和导水管周围病变与WE一致。低血清硫胺素水平证实了诊断。大剂量静脉注射硫胺素导致神经系统进行性改善。非酒精性术后ICU患者的WE常因重叠代谢紊乱、营养摄入不足和镇静掩盖神经体征而被低估。MRI对早期诊断至关重要。重症医师、放射科医师、麻醉科医师和营养学家之间的多学科协作对于及时识别和治疗至关重要。本病例强调了警惕营养评估、早期神经影像学和经验硫胺素给药对ICU术后不明原因持续性昏迷患者预防不可逆神经损伤的重要性。
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引用次数: 0
Hyperenhancing paravertebral mass in an adolescent: A rare presentation of unicentric Castleman disease 青少年椎旁高强化肿块:罕见的单中心Castleman病
Q4 Medicine Pub Date : 2025-12-19 DOI: 10.1016/j.radcr.2025.11.078
Christopher Magloire BS , Ricardo Navarro MD , Anna Tarasova MD , Mark Podberezin MD , Lynn Model MD , Anna Derman MD
Castleman disease (CD) is a rare lymphoproliferative disorder with two main subtypes: unicentric Castleman disease (UCD) and multicentric Castleman disease (MCD). UCD typically presents as a single mass, often in the mediastinum or retroperitoneum. We present a case of a 16-year-old male with an incidentally identified paravertebral mass on chest radiograph. Subsequent chest CT imaging revealed a hyperenhancing soft tissue mass adjacent to the T10 vertebral body, extending laterally along the ribs. Ultrasound-guided biopsy followed by video-assisted surgical resection confirmed the diagnosis of UCD. Paravertebral involvement in CD is rare, with only a limited number of cases reported in the literature. The differential diagnosis for paravertebral masses includes nerve sheath tumors and lymphomas, making pathological confirmation essential. Imaging features, such as hyperenhancement on arterial-phase CT may help distinguish CD from other potential diagnoses on imaging. Complete surgical resection remains the treatment of choice for UCD. This case underscores the importance of imaging in identifying and diagnosing CD, particularly in unusual locations like the paravertebral region, and highlights the necessity of accurate differential diagnosis to guide appropriate management.
Castleman病(CD)是一种罕见的淋巴细胞增殖性疾病,主要有两种亚型:单中心Castleman病(UCD)和多中心Castleman病(MCD)。UCD通常表现为单个肿块,常发生在纵隔或腹膜后。我们提出一个16岁的男性偶然发现椎旁肿块胸片。随后的胸部CT成像显示T10椎体附近有一个高度强化的软组织肿块,沿肋骨向外侧延伸。超声引导活检和视频辅助手术切除证实了UCD的诊断。椎旁受累在乳糜泻是罕见的,只有有限的病例报告在文献中。椎旁肿块的鉴别诊断包括神经鞘肿瘤和淋巴瘤,因此病理证实是必要的。影像特征,如动脉期CT上的高增强可以帮助将CD与其他潜在的影像学诊断区分开来。完全手术切除仍然是治疗UCD的首选。本病例强调了影像学在鉴别和诊断乳糜泻中的重要性,特别是在像椎旁区这样的不寻常部位,并强调了准确鉴别诊断以指导适当治疗的必要性。
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引用次数: 0
Refractory ileocolic variceal bleeding in hemorrhagic shock: Endoscopy-negative stigmata, failed TIPS, and successful control with targeted embolization of an ectopic varix 失血性休克中顽固性回结肠静脉曲张出血:内窥镜阴性,TIPS失败,靶向栓塞异位静脉曲张成功控制
Q4 Medicine Pub Date : 2025-12-18 DOI: 10.1016/j.radcr.2025.11.074
Rocklin Shumaker MD , Mohammad Abou El-Ezz BS , Erin Priddy MD , Yaw Ohene-Baah MD
Ectopic varices are portosystemic collaterals located outside the gastroesophageal region and represent a rare cause of variceal bleeding. They often pose diagnostic and therapeutic challenges due to their atypical locations and limited accessibility by conventional endoscopy. We report the case of a 68-year-old woman with a history of liver transplantation complicated by cirrhosis who presented with recurrent hematochezia and hemorrhagic shock. Endoscopic evaluation failed to identify the bleeding source. Computed tomography angiography (CTA) revealed varices in the distal superior mesenteric vein (SMV) territory involving the terminal ileum. The patient underwent transjugular intrahepatic portosystemic shunt (TIPS) placement, but bleeding persisted. Subsequent coil embolization of the ileocolic varix successfully controlled the hemorrhage. This case underscores the importance of recognizing ectopic varices as a rare source of gastrointestinal bleeding and highlights that TIPS alone may be insufficient, with adjunctive embolization often required for definitive management.
异位静脉曲张是位于胃食管区外的门静脉系统侧支,是引起静脉曲张出血的罕见原因。由于它们的非典型位置和传统内窥镜检查的局限性,它们经常构成诊断和治疗的挑战。我们报告的情况下,68岁的妇女肝移植史合并肝硬化谁提出了复发性血尿和失血性休克。内镜检查未发现出血源。计算机断层血管造影(CTA)显示静脉曲张在远端肠系膜上静脉(SMV)领域涉及回肠末端。患者接受了经颈静脉肝内门系统分流术(TIPS)放置,但出血持续存在。随后回肠曲张线圈栓塞成功地控制了出血。本病例强调了认识到异位静脉曲张是一种罕见的胃肠道出血来源的重要性,并强调仅使用TIPS可能是不够的,通常需要辅助栓塞来进行最终治疗。
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引用次数: 0
Central nervous system vasculitis mimicking a brain tumor: A case report 模拟脑肿瘤的中枢神经系统血管炎1例报告
Q4 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.radcr.2025.11.068
Uyen N.T. Nguyen BS , David Vo MD , Kari Hird MD , Victoria Wu MD , Vanessa Goodwill MD , Nikdokht Farid MD
Central nervous system (CNS) vasculitis is a rare inflammatory condition of blood vessels of the brain and spinal cord that can result in profound neurological symptoms mimicking many other pathologies. We present the case of a 36-year-old male who presented with subacute onset of progressive left-sided hemiparesis and refractory seizures. The diagnosis was challenging and required comprehensive review and integration of different imaging modalities, tissue sampling, and biochemical testing. This case highlights key imaging features which may aid in distinguishing central nervous system vasculitis from other etiologies such as malignancy.
中枢神经系统(CNS)血管炎是一种罕见的脑和脊髓血管炎症,可导致严重的神经系统症状,类似于许多其他病理。我们提出的情况下,一个36岁的男性谁提出了亚急性发作进行性左侧偏瘫和顽固性癫痫发作。诊断具有挑战性,需要综合检查和整合不同的成像方式、组织采样和生化测试。本病例突出了关键的影像学特征,这可能有助于将中枢神经系统血管炎与其他病因(如恶性肿瘤)区分开来。
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引用次数: 0
Perforated Meckel’s diverticulum: A rare evolution from diverticulitis to sepsis 穿孔梅克尔憩室:从憩室炎到败血症的罕见演变
Q4 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.radcr.2025.11.069
Manuela Montatore MD , Maria Grazia Capasso MD , Federica Masino MD , Marina Balbino MD , Giuseppe Guglielmi MD
Meckel’s diverticulum (MD) is the most common congenital anomaly of the gastrointestinal tract and affects ∼2% of the population. Although usually asymptomatic, MD may lead to complications including diverticulitis, bleeding, obstruction, and—rarely—perforation. Because perforated MD often mimics acute appendicitis, diagnosis before surgery is frequently missed. We describe a 58-year-old man who presented with right lower quadrant pain, fever, and nausea. Ultrasound excluded appendicitis and raised suspicion for MD. Contrast-enhanced CT confirmed an inflamed 3.5-cm MD with surrounding fat stranding, consistent with acute diverticulitis. The patient initially improved with conservative therapy but returned five days later with worsening pain and fever. A second CT revealed microperforation with peridiverticular extraluminal gas and fluid. Within 48 hours, clinical sepsis developed. A third CT demonstrated frank pneumoperitoneum and diffuse peritoneal free fluid. Exploratory laparotomy confirmed a perforated MD, which was resected, followed by ileostomy. Postoperative recovery was uneventful. Although rare, MD perforation is potentially life-threatening. This case uniquely illustrates the radiologic evolution from diverticulitis to microperforation and ultimately free perforation, documented across three consecutive CT examinations. Awareness of this progression may improve early recognition and timely surgical management of complicated MD.
梅克尔憩室(MD)是最常见的胃肠道先天性异常,影响约2%的人口。虽然MD通常无症状,但可导致憩室炎、出血、梗阻和极少穿孔等并发症。由于MD穿孔常与急性阑尾炎相似,手术前的诊断经常被遗漏。我们描述了一位58岁的男性,他表现为右下腹疼痛,发烧和恶心。超声排除阑尾炎,怀疑为MD。增强CT证实3.5 cm的MD炎症伴周围脂肪搁浅,符合急性憩室炎。患者最初通过保守治疗得到改善,但5天后复发,疼痛和发烧加剧。第二次CT显示微穿孔伴憩室周围腔外气体和液体。48小时内,临床脓毒症出现。第三次CT显示明显气腹和弥漫性腹膜游离液。剖腹探查证实MD穿孔,切除后行回肠造口术。术后恢复顺利。虽然罕见,但MD穿孔可能危及生命。该病例独特地说明了从憩室炎到微穿孔和最终自由穿孔的放射学演变,记录在连续三次CT检查中。对这种进展的认识可以提高对复杂MD的早期识别和及时的手术治疗。
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引用次数: 0
A primary fistula connecting a broad ligament leiomyoma to the cervix 连接宽韧带平滑肌瘤和子宫颈的原发性瘘管
Q4 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.radcr.2025.11.075
Kui Liang MD , Kunxue Gong MD , Xin Song MD , Wenjun Zhang MD
The endocervico-myomatous fistula is a rare condition that has been reported as a complication following uterine artery embolization. To date, no primary case of this nature has been documented in the PubMed database. The objective of this study was to present the diagnostic and therapeutic approaches for a primary fistula connecting a broad ligament leiomyoma to the cervix. A 35-year-old woman with vaginal bleeding, transvaginal ultrasound revealed features initially interpreted as a bicornuate unicollis uterus according to the ASRM 2021 classification, with 2 distinct uterine cavities communicating with a single cervix. The hysteroscopy revealed a prominent cavity on the left side of internal os of the cervical canal containing aged clots and mucus. The patient underwent laparoscopic resection of the pelvic lesion, subsequent surgical findings confirmed this to be a broad ligament leiomyoma with fistula formation rather than a true Müllerian anomaly. The postoperative pathology revealed the presence of leiomyoma with hyaloid degeneration. The patient had uneventful postoperative recovery. This case underscores the rare presentation of a broad ligament leiomyoma with fistula formation as a differential diagnostic consideration for bicornuate unicollis uterus in gynecological ultrasonography. A systematic literature review revealed no analogous reports, highlighting the uniqueness and instructional value of this case.
宫颈内肌瘤瘘管是一种罕见的情况,已报道的并发症后,子宫动脉栓塞。到目前为止,PubMed数据库中还没有记录这种性质的主要病例。本研究的目的是介绍连接宽韧带平滑肌瘤至子宫颈的原发性瘘的诊断和治疗方法。女性,35岁,阴道出血,经阴道超声检查发现特征,根据ASRM 2021分类,最初解释为双角状单颈子宫,2个不同的子宫腔与单个子宫颈相通。宫腔镜检查显示宫颈管内腔左侧有一个突出的腔,腔内有积液和黏液。患者接受腹腔镜切除盆腔病变,随后的手术结果证实这是一个宽韧带平滑肌瘤并瘘形成,而不是真正的勒氏管异常。术后病理显示为平滑肌瘤伴透明体变性。患者术后恢复顺利。本病例强调了罕见的宽韧带平滑肌瘤合并瘘形成的表现,作为妇科超声检查双角状单头子宫的鉴别诊断考虑。系统的文献回顾没有发现类似的报道,突出了本病例的独特性和指导价值。
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引用次数: 0
Pediatric case of trichobezoar leading to gastric perforation 小儿毛粪导致胃穿孔1例
Q4 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.radcr.2025.11.060
Rahaf Almoallim MD , Nadia Safa MD , Arbaaz Patel MD , Helene Flageole MD, MSc , Muhammed Danish Barakzai MBBS, FCPS, FRCR
Trichobezoars, or hairballs, are rare gastrointestinal masses often associated with psychiatric disorders like trichotillomania and trichophagia. Mostly seen among young females, they can cause severe gastrointestinal complications, including gastric ulceration and, subsequently, perforation. We reported a case of a young female with abdominal pain and vomiting diagnosed with a perforated gastric ulcer secondary to a bezoar. After emergency surgery and postoperative care, psychiatric evaluation confirmed trichotillomania with trichophagia which ultimately aided in the development of a comprehensive care plan. This case underscores the importance of considering trichobezoars in similar cases and highlights the role of emergent care.
毛虫或毛球是一种罕见的胃肠道肿块,通常与拔毛癖和拔毛癖等精神疾病有关。主要见于年轻女性,可引起严重的胃肠道并发症,包括胃溃疡和随后的穿孔。我们报告了一例年轻女性腹痛和呕吐诊断为穿孔胃溃疡继发于牛黄。经过紧急手术和术后护理,精神病学评估证实拔毛癖与拔毛症,最终有助于制定全面的护理计划。该病例强调了在类似病例中考虑毛虫病的重要性,并强调了紧急护理的作用。
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引用次数: 0
Double superior vena cava and anomalous left atrial drainage of persistent left SVC: A case report 持续性左侧SVC双上腔静脉伴左房异常引流1例
Q4 Medicine Pub Date : 2025-12-17 DOI: 10.1016/j.radcr.2025.11.065
Parisa Pishdad MD , Parham Heidari MD , Amirhossein Soltani MD , Mohsen Salimi MD
Persistent left superior vena cava (PLSVC) is an uncommon developmental variation of the thoracic venous system, sometimes accompanied by a duplicated superior vena cava (SVC). While often asymptomatic when draining into the right atrium, drainage toward the left atrium could lead to a right-to-left shunt and potential compromise of whole-body oxygen delivery. This report describes a 48-year-old male patient with hypertension and chronic tobacco use who was evaluated for dyspnea and leg edema. Imaging revealed a double SVC, where the left-sided vessel connected directly to the left atrium. Despite this anomaly, the patient exhibited no significant hypoxemia or cyanosis, likely due to long-term compensatory mechanisms. This report underscores the need to consider vascular anomalies in imaging interpretation, particularly when findings are incidental. It also underscores the role of contrast-enhanced CT in identifying rare anatomical variants and the potential for such anomalies to remain clinically silent despite physiological significance.
持续性左上腔静脉(PLSVC)是一种罕见的胸静脉系统发育变异,有时伴有重复的上腔静脉(SVC)。虽然在向右心房引流时通常无症状,但向左心房引流可能导致右至左分流和全身氧气输送的潜在损害。这篇报告描述了一个48岁的男性高血压患者和慢性烟草使用谁是评估呼吸困难和腿部水肿。成像显示双SVC,左侧血管直接连接左心房。尽管存在这种异常,但患者并未表现出明显的低氧血症或发绀,这可能是由于长期代偿机制。本报告强调了在影像学解释中考虑血管异常的必要性,特别是当发现是偶然的。它还强调了对比增强CT在识别罕见解剖变异方面的作用,以及尽管具有生理意义,但这种异常在临床上仍保持沉默的可能性。
{"title":"Double superior vena cava and anomalous left atrial drainage of persistent left SVC: A case report","authors":"Parisa Pishdad MD ,&nbsp;Parham Heidari MD ,&nbsp;Amirhossein Soltani MD ,&nbsp;Mohsen Salimi MD","doi":"10.1016/j.radcr.2025.11.065","DOIUrl":"10.1016/j.radcr.2025.11.065","url":null,"abstract":"<div><div>Persistent left superior vena cava (PLSVC) is an uncommon developmental variation of the thoracic venous system, sometimes accompanied by a duplicated superior vena cava (SVC). While often asymptomatic when draining into the right atrium, drainage toward the left atrium could lead to a right-to-left shunt and potential compromise of whole-body oxygen delivery. This report describes a 48-year-old male patient with hypertension and chronic tobacco use who was evaluated for dyspnea and leg edema. Imaging revealed a double SVC, where the left-sided vessel connected directly to the left atrium. Despite this anomaly, the patient exhibited no significant hypoxemia or cyanosis, likely due to long-term compensatory mechanisms. This report underscores the need to consider vascular anomalies in imaging interpretation, particularly when findings are incidental. It also underscores the role of contrast-enhanced CT in identifying rare anatomical variants and the potential for such anomalies to remain clinically silent despite physiological significance.</div></div>","PeriodicalId":53472,"journal":{"name":"Radiology Case Reports","volume":"21 3","pages":"Pages 1145-1149"},"PeriodicalIF":0.0,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145791319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Radiology Case Reports
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