Restauración volumétrica autóloga en pacientes con hemiatrofia adiposa facial

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Revista Medica Clinica Las Condes Pub Date : 2024-09-01 DOI:10.1016/j.rmclc.2024.08.005
Alicia María Tamayo-Carbón MD , Gloribeth Carrasco MD , Melvis Anaya-Blanco MD , Zainela Labordes-López MD , Miguel del Toro-Pazos MD , Diana Katherine Cuastumal-Figueroa MD
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Abstract

Introduction

Facial lipoatrophy lacks standard clinical criteria for its diagnosis and treatment; however, patients with hemifacial atrophy increase, affecting the mental health of patients who suffer from it. Lipografting has been rescued as an effective and safe treatment option.

Objective

To show the results of autologous volumetric restoration in patients with facial adipose hemiatrophy.

Method

Multicenter, descriptive, longitudinal and prospective study carried out on 29 patients treated at the Hermanos Ameijeiras Hospital, Cuba and the EIMEC clinic, Spain in the period from July 2018 to July 2023. Both sexes were included, between 19 and 75 years old, with facial asymmetry due to unilateral decrease in subcutaneous cellular tissue.

Results

The average age was 47.9 years. Women predominated with 79.3%. The most common etiologies were idiopathic, autoimmune and orbital trauma, each accounting for 17.2%. According to the degree of severity, grade II was the highest, with 65.5%, and grade III represented 34.5% of the total. Regarding the amount of grafted adipose tissue, 62.1% of the cases were 31 to 60 ml, and 27.6% more than 60 ml. According to the number of graft applications, 72.4% required one and 27.6% two applications. 93.1% had no complications and 6.9% reported 50% reabsorption of the graft. Patient satisfaction reached 100% and the results were classified as good in 86.21%; when there was improvement, without complications as well as patient satisfaction.

Conclusion

Autologous lipotransfer assisted with adipose tissue stem cells is a safe treatment option that offers good results in correcting asymmetry caused by hemifacial lipoatrophy.
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面部脂肪半萎缩患者的自体容积修复
导言面部脂肪萎缩缺乏标准的临床诊断和治疗标准;然而,半面神经萎缩患者不断增加,影响了患者的心理健康。脂肪移植作为一种有效、安全的治疗方法已被救治。方法在 2018 年 7 月至 2023 年 7 月期间,对古巴 Hermanos Ameijeiras 医院和西班牙 EIMEC 诊所治疗的 29 名患者进行多中心、描述性、纵向和前瞻性研究。研究对象男女不限,年龄在 19 岁至 75 岁之间,因单侧皮下细胞组织减少而导致面部不对称。女性居多,占 79.3%。最常见的病因是特发性、自身免疫性和眼眶外伤,各占 17.2%。根据严重程度,II 级最高,占 65.5%,III 级占 34.5%。就移植脂肪组织的量而言,62.1%的病例为 31 至 60 毫升,27.6%的病例超过 60 毫升。根据移植次数,72.4%的病例需要移植一次,27.6%的病例需要移植两次。93.1%的病例没有出现并发症,6.9%的病例报告移植物有50%被再次吸收。患者满意度达到100%,86.21%的患者认为效果良好,即有改善、无并发症和患者满意。
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来源期刊
Revista Medica Clinica Las Condes
Revista Medica Clinica Las Condes MEDICINE, GENERAL & INTERNAL-
CiteScore
0.80
自引率
0.00%
发文量
65
审稿时长
81 days
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