Intelligence algorithm for the treatment of gastrointestinal diseases based on immune monitoring and neuroscience: A revolutionary tool for translational medicine

IF 6.2 2区 工程技术 Q1 ENGINEERING, MULTIDISCIPLINARY alexandria engineering journal Pub Date : 2024-11-17 DOI:10.1016/j.aej.2024.11.028
Liangyu Li , Xuewen Qin , Guangwei Wang , Siyi Li , Xudong Li , Lizhong Guo , Javier Santos , Ana María Gonzalez-Castro , Yanyang Tu , Yi Qin
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引用次数: 0

Abstract

The research team has developed an information system based on clinical blood cell analysis and designed and implemented highly innovative algorithms. A neural network model was created based on these feature data of the blood cell population. Artificial intelligence algorithms can label susceptible populations for digestive tract cancer with an accuracy rate of over 80 %. A multi universe optimized BP neural network model was implemented based on TCGA data of common immune antigens in clinical laboratories. The working mechanism of this model is to assign values to the parameters of the BP neural network by using the process of searching for the best fitness in multiple universes. This model can predict the five-year survival rate of patients based on immunohistochemical data. Based on these data, an AI algorithm was used to develop a clinical prognostic model with an accuracy rate of over 99 %. The research team used single-cell sequencing data to locate cell subtypes in the features of immunohistochemical data, providing a biological basis for artificial intelligence models. The research team explored the potential biological mechanisms of cancer progression and occurrence based on gastrointestinal neuroendocrine products, and these algorithms have contributed to the prediction of cancer survival and incidence,team invented a simple and efficient algorithm.
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基于免疫监测和神经科学的胃肠道疾病治疗智能算法:转化医学的革命性工具
研究小组开发了一个基于临床血细胞分析的信息系统,并设计和实施了高度创新的算法。根据血细胞群的这些特征数据,建立了一个神经网络模型。人工智能算法可以标记消化道癌症的易感人群,准确率超过 80%。基于临床实验室常见免疫抗原的 TCGA 数据,实现了多宇宙优化 BP 神经网络模型。该模型的工作机制是通过在多个宇宙中寻找最佳适配度的过程为 BP 神经网络的参数赋值。该模型可根据免疫组化数据预测患者的五年生存率。在这些数据的基础上,使用人工智能算法开发了一个临床预后模型,准确率超过 99%。研究小组利用单细胞测序数据定位免疫组化数据特征中的细胞亚型,为人工智能模型提供了生物学基础。研究团队基于胃肠道神经内分泌产物,探索了癌症进展和发生的潜在生物学机制,这些算法为预测癌症生存率和发病率做出了贡献,团队发明了一种简单高效的算法。
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来源期刊
alexandria engineering journal
alexandria engineering journal Engineering-General Engineering
CiteScore
11.20
自引率
4.40%
发文量
1015
审稿时长
43 days
期刊介绍: Alexandria Engineering Journal is an international journal devoted to publishing high quality papers in the field of engineering and applied science. Alexandria Engineering Journal is cited in the Engineering Information Services (EIS) and the Chemical Abstracts (CA). The papers published in Alexandria Engineering Journal are grouped into five sections, according to the following classification: • Mechanical, Production, Marine and Textile Engineering • Electrical Engineering, Computer Science and Nuclear Engineering • Civil and Architecture Engineering • Chemical Engineering and Applied Sciences • Environmental Engineering
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