{"title":"Wirefree Electrochemistry for Enhanced Detection and Treatment of Disease","authors":"Oisín Foley Doyle , Robert J. Forster","doi":"10.1016/j.elecom.2024.107832","DOIUrl":null,"url":null,"abstract":"<div><div>Wirefree, or bipolar electrochemistry, BPE, has the potential to transform patient outcomes through early diagnosis using ultrasensitive sensors for multiple biomarkers and personalised treatments such as enhanced cell growth, differentiation and destruction as well as local delivery of therapeutics. We highlight the emerging field of wirefree electroceuticals and show how BPE could enable precise modulation of neural circuits, non-pharmaceutical therapies for conditions like Parkinson’s disease and chronic pain management, as well as on-demand drug delivery with high spatial and temporal precision. Moreover, it explores the integration of advanced nanomaterials illustrating their pivotal role in enhancing electrode performance and biocompatibility, thereby maximising their potential diagnostic and therapeutic efficacy especially <em>in vivo</em>.</div></div>","PeriodicalId":304,"journal":{"name":"Electrochemistry Communications","volume":"169 ","pages":"Article 107832"},"PeriodicalIF":4.7000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Electrochemistry Communications","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1388248124001759","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ELECTROCHEMISTRY","Score":null,"Total":0}
引用次数: 0
Abstract
Wirefree, or bipolar electrochemistry, BPE, has the potential to transform patient outcomes through early diagnosis using ultrasensitive sensors for multiple biomarkers and personalised treatments such as enhanced cell growth, differentiation and destruction as well as local delivery of therapeutics. We highlight the emerging field of wirefree electroceuticals and show how BPE could enable precise modulation of neural circuits, non-pharmaceutical therapies for conditions like Parkinson’s disease and chronic pain management, as well as on-demand drug delivery with high spatial and temporal precision. Moreover, it explores the integration of advanced nanomaterials illustrating their pivotal role in enhancing electrode performance and biocompatibility, thereby maximising their potential diagnostic and therapeutic efficacy especially in vivo.
期刊介绍：
Electrochemistry Communications is an open access journal providing fast dissemination of short communications, full communications and mini reviews covering the whole field of electrochemistry which merit urgent publication. Short communications are limited to a maximum of 20,000 characters (including spaces) while full communications and mini reviews are limited to 25,000 characters (including spaces). Supplementary information is permitted for full communications and mini reviews but not for short communications. We aim to be the fastest journal in electrochemistry for these types of papers.
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