Disability status investigation and risk prediction model for middle-aged and older adults in Anhui Province: A derivation and validation study

IF 2.9 4区 医学 Q2 Medicine Clinical and Experimental Pharmacology and Physiology Pub Date : 2024-11-18 DOI:10.1111/1440-1681.70005
Jing Li, Shu Wang, Yan-Bei Zhang
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Abstract

This study investigated the disability status of middle-aged and older adults in Anhui Province, China, with a primary focus on physical disability, and constructed a nomogram to predict disability risk. Data was collected through a province-wide questionnaire survey conducted in 16 cities and counties from January to December 2021, involving 3386 participants aged 60 years and above. The abilities of daily living (ADL) scale assessed participants' comprehensive ability. Risk factors for disability were identified using least absolute shrinkage and selection operator and logistic regression, highlighting six independent factors: age, poor sleep quality, depression, malnutrition, stroke, and the number of comorbid chronic diseases. A nomogram prediction model was then established and validated internally and externally. The model demonstrated good fit according to the Hosmer–Lemeshow test and provided significant benefits across various thresholds, as shown by decision curve analysis. This nomogram accurately and quickly identifies high-risk groups, aiding in early intervention.

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安徽省中老年人残疾状况调查与风险预测模型:推导与验证研究。
本研究调查了中国安徽省中老年人的残疾状况,主要关注肢体残疾,并构建了预测残疾风险的提名图。数据是通过 2021 年 1 月至 12 月在全省 16 个市、县进行的问卷调查收集的,涉及 3386 名 60 岁及以上的参与者。日常生活能力(ADL)量表评估参与者的综合能力。利用最小绝对缩减和选择算子以及逻辑回归确定了残疾的风险因素,突出了六个独立因素:年龄、睡眠质量差、抑郁、营养不良、中风和合并慢性病的数量。然后建立了一个提名图预测模型,并进行了内部和外部验证。根据 Hosmer-Lemeshow 检验,该模型显示出良好的拟合度,并通过决策曲线分析表明,该模型在不同阈值下均具有显著优势。该预测模型能准确、快速地识别高危人群,有助于早期干预。
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来源期刊
CiteScore
6.20
自引率
0.00%
发文量
128
审稿时长
6 months
期刊介绍: Clinical and Experimental Pharmacology and Physiology is an international journal founded in 1974 by Mike Rand, Austin Doyle, John Coghlan and Paul Korner. Our focus is new frontiers in physiology and pharmacology, emphasizing the translation of basic research to clinical practice. We publish original articles, invited reviews and our exciting, cutting-edge Frontiers-in-Research series’.
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