Diagnostic accuracy analysis of SARC-F, its modified versions and the Quality of Life in Sarcopenia questionnaire in screening for sarcopenia in nursing home residents

IF 2.4 4区医学 Q3 GERIATRICS & GERONTOLOGY Geriatrics & Gerontology International Pub Date : 2024-11-18 DOI:10.1111/ggi.15020

Hilal ŞİMŞEK, Aslı UÇAR

{"title":"Diagnostic accuracy analysis of SARC-F, its modified versions and the Quality of Life in Sarcopenia questionnaire in screening for sarcopenia in nursing home residents","authors":"Hilal ŞİMŞEK, Aslı UÇAR","doi":"10.1111/ggi.15020","DOIUrl":null,"url":null,"abstract":"<div>\n \n <section>\n \n <h3> Aim</h3>\n \n <p>Sarcopenia, which is among the most important geriatric syndromes, is also a public health challenge. This study evaluated the performance of the SARC-F, its modified versions and the Quality of Life in Sarcopenia (SarQoL) in screening for sarcopenia.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>In the diagnostic accuracy study carried out with a total of 195 nursing home residents, sarcopenia was evaluated according to the European Working Group on Sarcopenia in Older Persons 2 algorithm. For SARC-CalFs, the calf circumference standard and its population-specific reference (31 cm, 32/33 cm, respectively) were used, whereas for SARC + elderly and body mass index information, age (>75 years) and body mass index (<21 kg/m<sup>2</sup>) were used. Screening test performance was evaluated with receiver operating characteristic analysis, and the optimal cut-off points were determined according to the Youden index.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The prevalence of sarcopenia was 33.8%. Although SarQoL and SARC-CalF scores were lower in individuals with sarcopenia, standard SARC-F and SARC-F + elderly and body mass index information scores were not different. SARC-F had the poorest screening performance, whereas the SarQoL scale had the best screening performance (area under the curve 0.502 vs 0.787). SARC-CalF (32/33 cm) had the best performance among the modified versions of SARC-F. The optimal cut-off point for SarQoL was <64.56, and its sensitivity in sarcopenia screening was 74.24% (95% CI 62.0–84.2) and its specificity was 79.07% (95% CI 71.0–85.7). All the modified versions of SARC-CalF had higher sensitivity and area under the curve compared with SARC-F.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>SarQoL screening performance might be conducive to providing clinical discrimination in a nursing home sample. Further research is needed for the use of SarQoL as a potential sarcopenia screening strategy. Additionally, SARC-CalFs, especially the population-specific SARC-CalF (32/33 cm), might improve screening performance compared with standard SARC-F. <b>Geriatr Gerontol Int 2024; 24: 1335–1342</b>.</p>\n </section>\n </div>","PeriodicalId":12546,"journal":{"name":"Geriatrics & Gerontology International","volume":"24 12","pages":"1335-1342"},"PeriodicalIF":2.4000,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Geriatrics & Gerontology International","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/ggi.15020","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Aim

Sarcopenia, which is among the most important geriatric syndromes, is also a public health challenge. This study evaluated the performance of the SARC-F, its modified versions and the Quality of Life in Sarcopenia (SarQoL) in screening for sarcopenia.

Methods

In the diagnostic accuracy study carried out with a total of 195 nursing home residents, sarcopenia was evaluated according to the European Working Group on Sarcopenia in Older Persons 2 algorithm. For SARC-CalFs, the calf circumference standard and its population-specific reference (31 cm, 32/33 cm, respectively) were used, whereas for SARC + elderly and body mass index information, age (>75 years) and body mass index (<21 kg/m²) were used. Screening test performance was evaluated with receiver operating characteristic analysis, and the optimal cut-off points were determined according to the Youden index.

Results

The prevalence of sarcopenia was 33.8%. Although SarQoL and SARC-CalF scores were lower in individuals with sarcopenia, standard SARC-F and SARC-F + elderly and body mass index information scores were not different. SARC-F had the poorest screening performance, whereas the SarQoL scale had the best screening performance (area under the curve 0.502 vs 0.787). SARC-CalF (32/33 cm) had the best performance among the modified versions of SARC-F. The optimal cut-off point for SarQoL was <64.56, and its sensitivity in sarcopenia screening was 74.24% (95% CI 62.0–84.2) and its specificity was 79.07% (95% CI 71.0–85.7). All the modified versions of SARC-CalF had higher sensitivity and area under the curve compared with SARC-F.

Conclusions

SarQoL screening performance might be conducive to providing clinical discrimination in a nursing home sample. Further research is needed for the use of SarQoL as a potential sarcopenia screening strategy. Additionally, SARC-CalFs, especially the population-specific SARC-CalF (32/33 cm), might improve screening performance compared with standard SARC-F. Geriatr Gerontol Int 2024; 24: 1335–1342.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

SARC-F 及其修订版与 "肌肉疏松症生活质量 "问卷在筛查疗养院居民肌肉疏松症方面的诊断准确性分析。

目的：肌肉疏松症是最重要的老年综合症之一，也是一项公共卫生挑战。本研究评估了 SARC-F、其修订版和肌肉疏松症生活质量（SarQoL）在筛查肌肉疏松症方面的表现：在对 195 名疗养院居民进行的诊断准确性研究中，根据欧洲老年人肌肉疏松症工作组 2 算法对肌肉疏松症进行了评估。对于 SARC-CalFs，使用了小腿围标准及其特定人群参考值（分别为 31 厘米、32/33 厘米），而对于 SARC + 老年人和体重指数信息，则使用了年龄（大于 75 岁）和体重指数（2）。筛查测试的性能通过接收器操作特征分析进行评估，并根据尤登指数确定了最佳截断点：结果：肌肉疏松症的发病率为 33.8%。虽然肌肉疏松症患者的 SarQoL 和 SARC-CalF 分数较低，但标准 SARC-F 和 SARC-F + 老年人及体重指数信息分数并无差异。SARC-F 的筛查效果最差，而 SarQoL 量表的筛查效果最好（曲线下面积为 0.502 vs 0.787）。SARC-CalF（32/33 厘米）是 SARC-F 改良版中筛查效果最好的。SarQoL 的最佳截断点是结论：在养老院样本中，SarQoL 的筛查性能可能有助于提供临床鉴别。将 SarQoL 作为一种潜在的肌肉疏松症筛查策略还需要进一步研究。此外，与标准 SARC-F 相比，SARC-CalF（尤其是针对特定人群的 SARC-CalF（32/33 厘米））可能会提高筛查性能。Geriatr Gerontol Int 2024; --：-----.

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Geriatrics & Gerontology International 医学-老年医学

CiteScore

5.50

自引率

6.10%

发文量

189

审稿时长

4-8 weeks

期刊介绍： Geriatrics & Gerontology International is the official Journal of the Japan Geriatrics Society, reflecting the growing importance of the subject area in developed economies and their particular significance to a country like Japan with a large aging population. Geriatrics & Gerontology International is now an international publication with contributions from around the world and published four times per year.