{"title":"Evaluation of Diagnostic Accuracy of Wideband Tympanometry Absorbance for Otosclerosis.","authors":"Navid Nourizadeh, Azam Ghezi, Mohamadreza Afzalzadeh, Saeedeh Hajebi Khaniki, Hadi Behzad, Setare Kafashan, Sadegh Jafarzadeh","doi":"10.1007/s12070-024-04876-5","DOIUrl":null,"url":null,"abstract":"<p><p>Otosclerosis is a common cause of hearing loss, yet diagnosing it remains a challenge. Wideband Tympanometry Absorbance (WTA) has been proposed as a potential tool for improving diagnostic accuracy. The aim of study was to investigate the diagnostic value of WTA in diagnosing otosclerosis by comparing its results in patients with clinically diagnosed otosclerosis and a normal control group. This prospective study was conducted in Mashhad, Iran, from 2022 to 2023, involving 64 participants including otosclerosis and control. Inclusion criteria for the otosclerosis group included a clinical diagnosis of otosclerosis confirmed by audiometric tests and conventional tympanometry, and eligibility for surgical intervention. The control group consisted of individuals with normal clinical audiometric and tympanometric results. Both groups underwent conventional and WTA tympanometric assessments. The evaluation of WTA involved 64 participants, divided evenly between otosclerosis a normal ears group. Conventional tympanometry at 226 Hz showed significant differences in compliance between otosclerosis and normal ears (<i>p</i> = 0.02). In contrast, at 1000 Hz did not demonstrate significant differences in compliance (<i>p</i> = 0.2). Also, WTA did not demonstrate significant differences in compliance (<i>p</i> > 0.9). Measurements of gradient and resonance across both 226 and 1000Hz frequencies showed no statistically significant differences. The sensitivity and specificity of WTA, evaluated through compliance, were 72% and 40%, respectively, with an area under the curve of 0.50. The study illustrates that while conventional tympanometry is effective in distinguishing otosclerosis from normal tympanic conditions, WTA shows limited diagnostic efficacy. The moderate sensitivity and specificity of WTA suggest that it should not be relied upon as the sole diagnostic tool.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12070-024-04876-5.</p>","PeriodicalId":49190,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"76 6","pages":"5119-5125"},"PeriodicalIF":0.6000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569078/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Otolaryngology and Head and Neck Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12070-024-04876-5","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/13 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0
Abstract
Otosclerosis is a common cause of hearing loss, yet diagnosing it remains a challenge. Wideband Tympanometry Absorbance (WTA) has been proposed as a potential tool for improving diagnostic accuracy. The aim of study was to investigate the diagnostic value of WTA in diagnosing otosclerosis by comparing its results in patients with clinically diagnosed otosclerosis and a normal control group. This prospective study was conducted in Mashhad, Iran, from 2022 to 2023, involving 64 participants including otosclerosis and control. Inclusion criteria for the otosclerosis group included a clinical diagnosis of otosclerosis confirmed by audiometric tests and conventional tympanometry, and eligibility for surgical intervention. The control group consisted of individuals with normal clinical audiometric and tympanometric results. Both groups underwent conventional and WTA tympanometric assessments. The evaluation of WTA involved 64 participants, divided evenly between otosclerosis a normal ears group. Conventional tympanometry at 226 Hz showed significant differences in compliance between otosclerosis and normal ears (p = 0.02). In contrast, at 1000 Hz did not demonstrate significant differences in compliance (p = 0.2). Also, WTA did not demonstrate significant differences in compliance (p > 0.9). Measurements of gradient and resonance across both 226 and 1000Hz frequencies showed no statistically significant differences. The sensitivity and specificity of WTA, evaluated through compliance, were 72% and 40%, respectively, with an area under the curve of 0.50. The study illustrates that while conventional tympanometry is effective in distinguishing otosclerosis from normal tympanic conditions, WTA shows limited diagnostic efficacy. The moderate sensitivity and specificity of WTA suggest that it should not be relied upon as the sole diagnostic tool.
Supplementary information: The online version contains supplementary material available at 10.1007/s12070-024-04876-5.
期刊介绍：
Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress.
IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc.
The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world.
The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members.
Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
