Is it time to reframe resuscitation in trauma?

IF 2.7 3区 医学 Q1 EMERGENCY MEDICINE Emergency Medicine Journal Pub Date : 2024-11-19 DOI:10.1136/emermed-2024-214422
Rich Carden, Daniel Horner
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Abstract

Trauma remains a significant cause of mortality and morbidity. Non-compressible torso haemorrhage is one of the key drives of these mortality data. Our contemporary management has focused on damage control resuscitation, with a focus on haemorrhage control, haemostatic resuscitation and permissive hypotension. The evidence for permissive hypotension lacks the robustness as other treatments, such as tranexamic acid. Despite this clinicians still target arbitrary systolic blood pressure cutoffs as both goals and ceilings of therapy. In this paper, we suggest that perhaps more consideration should be given to the diastolic blood pressure in bleeding trauma patients. The diastolic blood pressure is critical for coronary perfusion, and in turn the cardiac output responsible for cerebral blood flow. We suggest that a move to reframing resuscitation in terms of physiology may change the way that we resuscitate these patients and allow for more nuanced treatment strategies.

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现在是重塑创伤复苏的时候了吗?
创伤仍然是导致死亡和发病的重要原因。不可压缩的躯干大出血是造成这些死亡数据的主要原因之一。我们当代的处理方法侧重于损伤控制复苏,重点是出血控制、止血复苏和允许性低血压。与其他治疗方法(如氨甲环酸)相比,允许性低血压缺乏强有力的证据。尽管如此,临床医生仍将任意的收缩压临界值作为治疗的目标和上限。在本文中,我们建议或许应更多地考虑出血创伤患者的舒张压。舒张压对冠状动脉灌注至关重要,而冠状动脉灌注又反过来影响着脑血流的心输出量。我们认为,从生理学角度重新审视复苏,可能会改变我们对这些病人的复苏方式,并允许采取更细致的治疗策略。
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来源期刊
Emergency Medicine Journal
Emergency Medicine Journal 医学-急救医学
CiteScore
4.40
自引率
6.50%
发文量
262
审稿时长
3-8 weeks
期刊介绍: The Emergency Medicine Journal is a leading international journal reporting developments and advances in emergency medicine and acute care. It has relevance to all specialties involved in the management of emergencies in the hospital and prehospital environment. Each issue contains editorials, reviews, original research, evidence based reviews, letters and more.
期刊最新文献
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