Quang Khai Dao, Thuy Quynh Mai, Thanh Van Pham, An Bang Ngac, Chi Hieu Hoang, Ewald Janssens, Hanh Hong Mai
{"title":"ZnO nanorods grown on Cu wire mesh provide a high sensitivity non-enzymatic absorbance glucose sensor","authors":"Quang Khai Dao, Thuy Quynh Mai, Thanh Van Pham, An Bang Ngac, Chi Hieu Hoang, Ewald Janssens, Hanh Hong Mai","doi":"10.1007/s00604-024-06845-9","DOIUrl":null,"url":null,"abstract":"<div><p> A highly sensitive non-enzymatic absorption-based glucose sensor is introduced that combines ZnO nanorods with the ferrous oxidation-xylenol orange (FOX) assay. ZnO nanorods were successfully synthesized on the surface of a copper wire mesh, exhibiting high crystallinity, purity, and a large surface area. The glucose sensor displays a high sensitivity of 0.394 mM<sup>−1</sup> in a wide linear detection range (0 − 6 mM), along with a low limit of detection of 0.25 mM. The proposed assay has an excellent selectivity towards glucose compared with other sugars such as sucrose, maltose, and fructose. The potential use of the non-enzymatic absorbance sensor for diabetes monitoring is demonstrated by measuring the glucose concentration in human blood serum, obtaining values that are consistent with clinical analysis.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-024-06845-9","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
A highly sensitive non-enzymatic absorption-based glucose sensor is introduced that combines ZnO nanorods with the ferrous oxidation-xylenol orange (FOX) assay. ZnO nanorods were successfully synthesized on the surface of a copper wire mesh, exhibiting high crystallinity, purity, and a large surface area. The glucose sensor displays a high sensitivity of 0.394 mM−1 in a wide linear detection range (0 − 6 mM), along with a low limit of detection of 0.25 mM. The proposed assay has an excellent selectivity towards glucose compared with other sugars such as sucrose, maltose, and fructose. The potential use of the non-enzymatic absorbance sensor for diabetes monitoring is demonstrated by measuring the glucose concentration in human blood serum, obtaining values that are consistent with clinical analysis.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
