Validation and reproducibility of the International Study of Asthma and Allergies in Childhood (ISAAC) Written Allergic Rhinitis Questionnaire for phone survey in children aged 6‒7 years
Priscilla Campos , Solange O.R. Valle , Antônio José Ledo Alves da Cunha , Fábio Chigres Kuschnir , Dirceu Solé
{"title":"Validation and reproducibility of the International Study of Asthma and Allergies in Childhood (ISAAC) Written Allergic Rhinitis Questionnaire for phone survey in children aged 6‒7 years","authors":"Priscilla Campos , Solange O.R. Valle , Antônio José Ledo Alves da Cunha , Fábio Chigres Kuschnir , Dirceu Solé","doi":"10.1016/j.bjorl.2024.101531","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To validate and assess the reproducibility of the ISAAC Written Allergic Rhinitis Questionnaire (WARQ) for children aged between 6 and 7 years by telephone contact.</div></div><div><h3>Methods</h3><div>Observational study through interviews with guardians of children aged 6–7 years using the ISAAC Allergic Rhinitis (AR) module questionnaire in three different phases separated by 2 weeks each: telephone interviews in the first and third contacts and face-to-face interviews, with the same guardian of telephone interviews, in the second contact. Reproducibility was estimated using the Kappa index and validation using the sensitivity and specificity coefficients.</div></div><div><h3>Results</h3><div>Data from 94 children (48 from the allergic rhinitis Control Group ‒ CG) were analyzed. Reproducibility showed perfect agreement (100%) for the question number 1 – Which refers to the symptoms of AR, ever: “Has your child ever had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” and for the question number 2 – Which refers to current symptoms of AR: “In the past 12 months, has your child had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” A strong agreement was also observed for the question number 3 (κ = 0.871) – it defines the presence of comorbidity of allergic rhinoconjuntivitis “In the past 12 months, has this nose problem been accompanied by itchy-watery eyes?” The validation showed high specificity (≥76.7%) and sensitivity (≥98%) for all questions, except for the ones related to seasonality and intensity of symptoms.</div></div><div><h3>Conclusions</h3><div>Our results showed that the ISAAC AR module questionnaire by telephone interviews has good reproducibility and high agreement with the clinical diagnosis of AR. It may be an appropriate alternative tool in epidemiological studies of childhood AR, especially in periods of social isolation, such as Coronavirus pandemic.</div></div><div><h3>Level of evidence</h3><div>Cohort Study. Level IV</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 2","pages":"Article 101531"},"PeriodicalIF":1.7000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brazilian Journal of Otorhinolaryngology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1808869424001460","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To validate and assess the reproducibility of the ISAAC Written Allergic Rhinitis Questionnaire (WARQ) for children aged between 6 and 7 years by telephone contact.
Methods
Observational study through interviews with guardians of children aged 6–7 years using the ISAAC Allergic Rhinitis (AR) module questionnaire in three different phases separated by 2 weeks each: telephone interviews in the first and third contacts and face-to-face interviews, with the same guardian of telephone interviews, in the second contact. Reproducibility was estimated using the Kappa index and validation using the sensitivity and specificity coefficients.
Results
Data from 94 children (48 from the allergic rhinitis Control Group ‒ CG) were analyzed. Reproducibility showed perfect agreement (100%) for the question number 1 – Which refers to the symptoms of AR, ever: “Has your child ever had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” and for the question number 2 – Which refers to current symptoms of AR: “In the past 12 months, has your child had a problem with sneezing or a runny or a blocked nose when he/she did not have a cold or the flu?” A strong agreement was also observed for the question number 3 (κ = 0.871) – it defines the presence of comorbidity of allergic rhinoconjuntivitis “In the past 12 months, has this nose problem been accompanied by itchy-watery eyes?” The validation showed high specificity (≥76.7%) and sensitivity (≥98%) for all questions, except for the ones related to seasonality and intensity of symptoms.
Conclusions
Our results showed that the ISAAC AR module questionnaire by telephone interviews has good reproducibility and high agreement with the clinical diagnosis of AR. It may be an appropriate alternative tool in epidemiological studies of childhood AR, especially in periods of social isolation, such as Coronavirus pandemic.
目的通过电话联系，验证和评估针对6至7岁儿童的ISAAC过敏性鼻炎书面问卷（WARQ）的可重复性：通过对 6-7 岁儿童监护人的访谈进行观察研究，使用 ISAAC 过敏性鼻炎 (AR) 模块问卷，分三个不同阶段进行，每个阶段间隔 2 周：第一次和第三次联系时进行电话访谈，第二次联系时与电话访谈的同一监护人进行面对面访谈。再现性采用卡帕指数估算，验证性采用灵敏度和特异性系数估算：分析了 94 名儿童（48 名来自过敏性鼻炎对照组--CG）的数据。可重复性显示，在问题 1（指曾经出现过的 AR 症状）"您的孩子在没有伤风感冒的情况下，是否曾经出现过打喷嚏、流鼻涕或鼻塞的问题？第 3 个问题（κ = 0.871）也具有很高的一致性--它定义了是否存在过敏性鼻并发症："在过去 12 个月中，这种鼻部问题是否伴有眼睛发痒流泪？验证结果显示，除了与季节性和症状强度有关的问题外，所有问题的特异性（≥76.7%）和敏感性（≥98%）都很高：我们的研究结果表明，通过电话访问进行的 ISAAC AR 模块问卷与 AR 的临床诊断具有良好的重现性和高度一致性。在儿童 AR 的流行病学研究中，尤其是在冠状病毒大流行等社会隔离时期，它可能是一种合适的替代工具：证据等级：队列研究：
期刊介绍：
Brazilian Journal of Otorhinolaryngology publishes original contributions in otolaryngology and the associated areas (cranio-maxillo-facial surgery and phoniatrics). The aim of this journal is the national and international divulgation of the scientific production interesting to the otolaryngology, as well as the discussion, in editorials, of subjects of scientific, academic and professional relevance.
The Brazilian Journal of Otorhinolaryngology is born from the Revista Brasileira de Otorrinolaringologia, of which it is the English version, created and indexed by MEDLINE in 2005. It is the official scientific publication of the Brazilian Association of Otolaryngology and Cervicofacial Surgery. Its abbreviated title is Braz J Otorhinolaryngol., which should be used in bibliographies, footnotes and bibliographical references and strips.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
