Brazilian Journal of Otorhinolaryngology最新文献

Explainable machine learning model for predicting hearing recovery in unilateral sudden sensorineural hearing loss 预测单侧突发性感音神经性听力损失听力恢复的可解释机器学习模型。

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-12-17 DOI: 10.1016/j.bjorl.2025.101730

Jueting Wu , Ruru Chen , Yaxuan Liu , Feng Zhao , Huiying Chen , Xiaoyu Lin , Jiping Su

Objective

Sudden Sensorineural Hearing Loss (SSNHL) is routinely encountered in otolaryngology clinics. The prognosis of SSNHL varies dramatically and depends on multiple influence factors. This study aimed to develop an explainable Machine Learning (ML) model with easily accessible features to predict the prognosis of SSNHL.

Methods

This bi-center retrospective study included 534 patients with SSNHL. We randomly split the data into training and validation sets. Univariate analysis and Least Absolute Shrinkage and Selection Operator (LASSO) regression were employed to select predominant features, including demographic, disease-specific characteristics, and laboratory items. We evaluated the performance of five ML models constructed with six crucial variables using the Area Under the receiver operating characteristic Curve (AUC), accuracy, specificity, sensitivity, and F1 scores. These models were further calibrated by calibration curve and Brier score. Clinical utility was evaluated by Decision Curve Analysis (DCA). The Shapley Additive Explanations (SHAP) method was applied to interpret feature contribution and explain the ML models.

Results

The Random Forest (RF) model reached the highest AUC of 0.998. Its accuracy, sensitivity, specificity, and F1 score were 0.981, 0.963, 0.989, and 0.967, respectively. DCA curve analysis revealed a comparable net benefit of the models. The SHAP method revealed that the primary features were degree of hearing loss, audiogram type, age, Mean Corpuscular Volume (MCV), onset to treatment, and serum Albumin (ALB) accordingly.

Conclusions

The explainable ML model was superb in predicting hearing outcome and providing information on feature contributions. Clinicians can better understand the contributors to hearing recovery and guide aural rehabilitation using the SHAP method.

Level of evidence

Level 3.

目的：突发性感音神经性听力损失（SSNHL）是耳鼻喉科临床的常见病。SSNHL的预后差异很大，受多种影响因素的影响。本研究旨在建立一个可解释的机器学习（ML）模型，该模型具有易于访问的特征，用于预测SSNHL的预后。方法：本双中心回顾性研究纳入534例SSNHL患者。我们将数据随机分成训练集和验证集。采用单变量分析和最小绝对收缩和选择算子（LASSO）回归来选择主要特征，包括人口统计学、疾病特异性特征和实验室项目。我们使用受试者工作特征曲线下面积（Area Under the receiver operating characteristic Curve， AUC）、准确性、特异性、敏感性和F1评分来评估由六个关键变量构建的五种ML模型的性能。通过校正曲线和Brier评分对模型进行进一步校正。采用决策曲线分析（DCA）评价临床疗效。采用Shapley加性解释（SHAP）方法对特征贡献进行解释，对ML模型进行解释。结果：随机森林（RF）模型的AUC最高，为0.998。其准确性、敏感性、特异性和F1评分分别为0.981、0.963、0.989和0.967。DCA曲线分析显示了模型的可比净效益。SHAP方法显示的主要特征是听力损失程度、听力图类型、年龄、平均红细胞体积（MCV）、开始治疗和血清白蛋白（ALB）。结论：可解释的ML模型在预测听力结果和提供特征贡献信息方面非常出色。临床医生可以更好地了解听力恢复的影响因素，并使用SHAP方法指导听力康复。证据等级：三级。

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引用次数: 0

Artificial intelligence, emotional intelligence, and helplessness 人工智能、情商和无助感

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-12-05 DOI: 10.1016/j.bjorl.2025.101745

Otavio B. Piltcher , Claire Hopkins

引用次数: 0

P16INK4a protein expression associated with Head and Neck Squamous Cell Carcinoma: A perspective of a public health reference service in São Paulo P16INK4a蛋白表达与头颈部鳞状细胞癌相关：圣保罗公共卫生参考服务的视角

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-12-03 DOI: 10.1016/j.bjorl.2025.101741

Mariah Cristina Antunes do Nascimento , Ana Lívia Silva Galbiatti-Dias , Lucas Brumato Figueiredo , Ludimila Leite Marzochi , Márcia Maria Urbanin Castanhole-Nunes , Rafael Felipe Maciel Andrade , José Victor Maníglia , Lilian Castiglioni , Juliana Garcia de Oliveira-Cucolo , Érika Cristina Pavarino , Eny Maria Goloni-Bertollo

Objectives

Human Papillomavirus (HPV) may be a predictive biomarker predictor for clinical outcome and influence treatment decisions in patients with Head and Neck Squamous Cell Carcinoma (HNSCC).

Methods

We evaluated 253 patients with HNSCC from state of São Paulo, Brazil. The influence of p16^INK4a expression was analyzed with epidemiological and clinical variables.

Results

In total, 32.4% of tumors studied had positive (+) p16^INK4a protein expression, and 67.6% had negative. The variables were similar in both groups being the mostly with age under 64-years, male, white race, functional illiterate, smokers and alcoholics. The most affected primary site was oral cavity with T3/T4 tumoral stage, N1/N2/N3 nodals, M0 metastasis and III/IV clinical stage. Patients with oropharyngeal primary site and (+) p16^INK4a, clinical staging III and chemotherapy treatment had worse survival. The median time of distant metastasis-free was 38.3-months in oropharyngeal (+) p16^INK4a and 15.1-months in negative (−) p16^INK4a.

Conclusion

In the present study, the epidemiological variables are similar in both groups (Positive and negative p16^INK4a expression): age under 64-years, male, white, functionally illiterate, smokers and alcoholics. There is no association of p16^INK4a expression with primary site, however, the (−) p16^INK4a shows better overall survival, higher frequencies in distant metastasis and less free time of the disease. Although the literature shows a greater survival in oropharynx (+) p16^INK4a, our results are contradictory. It is suggested that future studies in different regions and with a larger sample size should be carried out to confirm these findings, because the patients who participated in the present study are only from a specific region of Brazil.

Level of evidence

2B.

目的：人乳头瘤病毒（HPV）可能是头颈部鳞状细胞癌（HNSCC）患者临床结果的预测性生物标志物预测因子，并影响治疗决策。方法：我们评估了来自巴西圣保罗州的253例HNSCC患者。结合流行病学和临床变量分析p16INK4a表达的影响。结果：在所研究的肿瘤中，p16INK4a蛋白阳性（+）表达占32.4%，阴性表达占67.6%。两组的变量相似，大多为64岁以下、男性、白种人、功能性文盲、吸烟者和酗酒者。原发部位以口腔为主，伴T3/T4期肿瘤、N1/N2/N3期淋巴结、M0期转移及III/IV期临床分期。口咽原发部位和（+）p16INK4a、临床分期为III期和化疗的患者生存率较差。口咽p16INK4a阳性患者无远处转移的中位时间为38.3个月，p16INK4a阴性患者为15.1个月。结论：在本研究中，p16INK4a阳性和阴性两组的流行病学变量相似：年龄在64岁以下，男性，白人，功能文盲，吸烟者和酗酒者。p16INK4a的表达与原发部位没有相关性，但（-）p16INK4a表现出更好的总生存率、更高的远处转移频率和更短的疾病空闲时间。虽然文献显示口咽部（+）p16INK4a的存活率更高，但我们的结果是矛盾的。由于参与本研究的患者仅来自巴西的一个特定地区，因此建议在未来进行不同地区和更大样本量的研究来证实这些发现。证据等级：2B。

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引用次数: 0

Hidden in plain sight: why diagnosing asymptomatic congenital cytomegalovirus (cCMV) changes everything 隐藏在显而易见的：为什么诊断无症状先天性巨细胞病毒（cCMV）改变一切。

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-12-02 DOI: 10.1016/j.bjorl.2025.101728

Vagner Antonio Rodrigues Silva, Nicolau Moreira Abrahão, Arthur Menino Castilho

引用次数: 0

Bilobed flap for lower lip reconstruction: A two-case series and technical considerations 双叶瓣下唇重建：两例系列和技术考虑

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-28 DOI: 10.1016/j.bjorl.2025.101738

Victor Bandini Vieira, Giovana Cruz Corsi, Rafael Pereira de Souza, Rafael De Cicco

引用次数: 0

miR-199a-5p inhibits malignant progression and enhances cisplatin sensitivity of nasopharyngeal carcinoma by targeting SLC1A5 miR-199a-5p通过靶向SLC1A5抑制鼻咽癌恶性进展，增强鼻咽癌顺铂敏感性

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-28 DOI: 10.1016/j.bjorl.2025.101739

Anchi Sun , Rongrong Lv , Zhiwei Xing , Yifan He , Xiaomin Wang , Hui Li , Qianqian Shao

Objective

The prevalence of Nasopharyngeal Carcinoma (NPC) is increasing, and the mortality of patients with cisplatin resistance is high. In this study, we aimed to elucidate several potential mechanisms of miR-199a-5p in regulating the progression and cisplatin resistance of NPC.

Methods

Relevant datasets were downloaded from the Gene Expression Omnibus (GEO) database to verify miR-199a-5p expression in NPC. The miR-199a-5p level was evaluated by RT-qPCR, and the prognostic significance was analyzed by K–M curve. Cell proliferation, migration, invasion and apoptosis were detected in vitro. The contents of Epithelial-Mesenchymal Transition (EMT) protein, apoptosis protein and SLC1A5 protein were detected by Western immunoblotting. DLR assay elucidated that miR-199a-5p targets SLC1A5. The effect of miR-199a-5p on subcutaneous tumor in nude mice was detected in vivo.

Results

We found that miR-199a-5p was differentially expressed in nasopharyngeal carcinoma, and patients with high expression showed good prognosis. It was also found to be associated with cisplatin resistance and showed low expression in HNE1/DDP cells. The up-regulation of miR-199a-5p can inhibit the proliferation, migration and invasion of NPC cells, and enhance cell apoptosis. The mechanism may be achieved by targeting SLC1A5.

Conclusion

The high expression of miR-199a-5p can inhibit SLC1A5 and thus the progression of NPC. At the same time, the high expression of miR-199a-5p can increase the sensitivity of NPC to cisplatin.

Level of evidence

Level 5.

目的鼻咽癌（NPC）的发病率呈上升趋势，顺铂耐药患者的死亡率较高。在这项研究中，我们旨在阐明miR-199a-5p调节鼻咽癌进展和顺铂耐药的几种潜在机制。方法从Gene Expression Omnibus （GEO）数据库下载相关数据集，验证miR-199a-5p在NPC中的表达。RT-qPCR检测miR-199a-5p水平，K-M曲线分析预后意义。体外检测细胞增殖、迁移、侵袭和凋亡。Western免疫印迹法检测上皮-间质转化（Epithelial-Mesenchymal Transition， EMT）蛋白、凋亡蛋白和SLC1A5蛋白的含量。DLR分析证实miR-199a-5p靶向SLC1A5。在体内检测miR-199a-5p对裸鼠皮下肿瘤的影响。结果我们发现miR-199a-5p在鼻咽癌中存在差异表达，高表达患者预后良好。它也被发现与顺铂耐药有关，并在HNE1/DDP细胞中低表达。上调miR-199a-5p可抑制鼻咽癌细胞的增殖、迁移和侵袭，促进细胞凋亡。其机制可能通过靶向SLC1A5来实现。结论miR-199a-5p高表达可抑制SLC1A5，从而抑制鼻咽癌的进展。同时，miR-199a-5p的高表达可增加鼻咽癌对顺铂的敏感性。证据等级：5级。

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引用次数: 0

Combined endoscopic and open frontolateral laryngectomy for glottic tumors involving the anterior commissure 内窥镜联合开放额外侧喉切除术治疗声门肿瘤累及前联合

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-28 DOI: 10.1016/j.bjorl.2025.101742

Leonardo Haddad , Fabio Pupo Ceccon , Leticia Angélica da Silva Souza , Beatrice Haase Ceccon , João Vitor Pincelli , Mateus Morais Aires

Objective

The combined endoscopic and open frontolateral laryngectomy technique has been proposed to balance oncologic safety with functional preservation in the management of glottic tumors involving the Anterior Commissure (AC). This study aims to describe this technique in detail, its indications, and to present our institution’s case series.

Methods

A retrospective review was conducted of all patients undergoing surgery for glottic lesions suspected of malignancy between 2017 and 2024 at a single institution. Patients treated with the combined endoscopic and open frontolateral laryngectomy approach were included. Surgical technique, indications, contraindications, and perioperative management were documented. Outcomes assessed included oncologic control, tracheostomy status, and laryngeal function.

Results

Among 138 patients treated surgically for suspected malignant glottic lesions, four patients underwent the combined approach. Tumor stages included T1b (n = 2), T2 (n = 1), and T3 (n = 1). All patients were male, with a mean age of 71.5-years. Local disease control was achieved in three patients (75%), while one T3 patient experienced recurrence requiring salvage radiotherapy, achieving subsequent disease control. All patients retained laryngeal function, with no need for permanent tracheostomy or reports of dysphagia. Postoperative dysphonia was characterized by roughness, breathiness, and high-pitched but functional voices.

Conclusion

The combined approach offers a feasible alternative for managing AC-involving glottic tumors, providing oncologic safety while preserving function. It enables precise tumor resection with limited sacrifice of normal tissue and the potential for phonation-preserving reconstruction. Given the small sample size, further studies are needed to validate its efficacy and long-term benefits.

Level of evidence

4.

目的探讨经内镜联合开放额外侧喉切除术治疗声门前连合（AC）肿瘤时兼顾肿瘤安全性和功能保护的方法。本研究旨在详细描述该技术，其适应症，并介绍本机构的病例系列。方法回顾性分析2017年至2024年在同一医院接受声门病变疑似恶性手术的所有患者。采用内窥镜和开放额外侧喉切除术联合入路治疗的患者包括在内。记录手术技术、适应症、禁忌症和围手术期处理。评估的结果包括肿瘤控制、气管造口状态和喉功能。结果138例疑似声门恶性病变行手术治疗的患者中，4例采用联合入路。肿瘤分期包括T1b （n = 2）、T2 （n = 1）和T3 （n = 1）。所有患者均为男性，平均年龄71.5岁。3例（75%）患者获得局部疾病控制，1例T3患者出现复发，需要补救性放疗，实现了后续疾病控制。所有患者均保留喉功能，无永久性气管切开术或吞咽困难报告。术后语音障碍的特征是粗糙、呼吸困难和高音调但功能正常的声音。结论联合入路是治疗ac累及声门肿瘤的可行选择，在保证功能的同时保证肿瘤的安全性。它可以精确切除肿瘤，同时限制正常组织的牺牲和保留发音重建的潜力。由于样本量小，需要进一步的研究来验证其疗效和长期效益。证据水平4。

{"title":"Combined endoscopic and open frontolateral laryngectomy for glottic tumors involving the anterior commissure","authors":"Leonardo Haddad , Fabio Pupo Ceccon , Leticia Angélica da Silva Souza , Beatrice Haase Ceccon , João Vitor Pincelli , Mateus Morais Aires","doi":"10.1016/j.bjorl.2025.101742","DOIUrl":"10.1016/j.bjorl.2025.101742","url":null,"abstract":"<div><h3>Objective</h3><div>The combined endoscopic and open frontolateral laryngectomy technique has been proposed to balance oncologic safety with functional preservation in the management of glottic tumors involving the Anterior Commissure (AC). This study aims to describe this technique in detail, its indications, and to present our institution’s case series.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of all patients undergoing surgery for glottic lesions suspected of malignancy between 2017 and 2024 at a single institution. Patients treated with the combined endoscopic and open frontolateral laryngectomy approach were included. Surgical technique, indications, contraindications, and perioperative management were documented. Outcomes assessed included oncologic control, tracheostomy status, and laryngeal function.</div></div><div><h3>Results</h3><div>Among 138 patients treated surgically for suspected malignant glottic lesions, four patients underwent the combined approach. Tumor stages included T1b (n = 2), T2 (n = 1), and T3 (n = 1). All patients were male, with a mean age of 71.5-years. Local disease control was achieved in three patients (75%), while one T3 patient experienced recurrence requiring salvage radiotherapy, achieving subsequent disease control. All patients retained laryngeal function, with no need for permanent tracheostomy or reports of dysphagia. Postoperative dysphonia was characterized by roughness, breathiness, and high-pitched but functional voices.</div></div><div><h3>Conclusion</h3><div>The combined approach offers a feasible alternative for managing AC-involving glottic tumors, providing oncologic safety while preserving function. It enables precise tumor resection with limited sacrifice of normal tissue and the potential for phonation-preserving reconstruction. Given the small sample size, further studies are needed to validate its efficacy and long-term benefits.</div></div><div><h3>Level of evidence</h3><div>4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"92 2","pages":"Article 101742"},"PeriodicalIF":1.8,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymphocyte-to-monocyte ratio as a clinical predictor in sudden sensorineural hearing loss 淋巴细胞/单核细胞比值作为突发性感音神经性听力损失的临床预测因子

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-26 DOI: 10.1016/j.bjorl.2025.101744

Elvan Onan, Ozgur Surmelioglu, Caglar Eker, Muhammed Dagkiran, Ilda Tanrisever Pehlivan, Berk Alsancak, Suleyman Ozdemir, Ozgur Tarkan, Mustafa Mete Kiroglu

Objective

This study evaluates the prognostic significance of systemic inflammatory markers ‒ NLR, LMR, PLR, and SII ‒ in patients with SSNHL.

Methods

This retrospective study included 120 patients diagnosed with SSNHL at the Otolaryngology Department of Hospital. Medical records from both SSNHL and healthy control groups were reviewed to collect demographic data, pure tone audiometry results, and routine blood parameters. Hearing recovery was assessed at baseline and after two months using Siegel's criteria, and patients were categorized as either recovered (complete, partial, or slight recovery) or unrecovered.

Results

Compared to controls, SSNHL patients showed significantly elevated neutrophil counts, platelet levels, NLR, PLR, and SII values. Statistically significant differences were observed between recovered and unrecovered groups in neutrophil count (p = 0.021), lymphocyte count (p = 0.001), PDW (p = 0.042), NLR (p = 0.001), PLR (p = 0.001), LMR (p = 0.001), and SII (p = 0.001). Logistic regression analysis identified low LMR as a significant independent predictor of poor prognosis (R² = 0.271).

Conclusion

Elevated NLR, PLR, and SII values may reflect inflammatory processes and microvascular dysfunction in SSNHL. Among these, LMR emerged as a novel and potentially valuable prognostic biomarker for predicting treatment outcomes.

Level of evidence

3.

目的评价全身炎症标志物NLR、LMR、PLR和SII在SSNHL患者中的预后意义。方法回顾性分析我院耳鼻喉科收治的120例SSNHL患者。对SSNHL组和健康对照组的医疗记录进行回顾，收集人口统计数据、纯音听力学结果和常规血液参数。在基线和两个月后使用Siegel标准评估听力恢复情况，并将患者分为完全恢复、部分恢复或轻微恢复或未恢复。结果与对照组相比，SSNHL患者中性粒细胞计数、血小板水平、NLR、PLR和SII值显著升高。恢复组与未恢复组中性粒细胞计数（p = 0.021）、淋巴细胞计数（p = 0.001）、PDW （p = 0.042）、NLR （p = 0.001）、PLR （p = 0.001）、LMR （p = 0.001）、SII （p = 0.001）差异有统计学意义。Logistic回归分析发现低LMR是不良预后的重要独立预测因子（R²= 0.271）。结论NLR、PLR和SII值升高可能反映SSNHL的炎症过程和微血管功能障碍。其中，LMR成为预测治疗结果的一种新颖且具有潜在价值的预后生物标志物。证据水平3。

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引用次数: 0

A case-control study on preauricular congenital fistula surgery outcomes by Propensity Score Matching (PSM) analysis 倾向评分匹配（PSM）分析耳前先天性瘘手术结果的病例对照研究

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-26 DOI: 10.1016/j.bjorl.2025.101729

Jibing Sun, Tingting Wang, Dong Chen, Yanyan Mao, Zhaomin Fan, Yuechen Han

Objective

To explore the propensity matching score to compare the clinical efficacy of infection localized and inflammatory quiescent stage I surgery in the treatment of congenital preauricular fistula.

Methods

120 patients with congenital preauricular fistula treated in our hospital from January 2022 to August 2023 were selected. The patients were divided into infection limited group (n = 63) and inflammation rest group (n = 57) according to the mode of operation. The two groups were matched at 1:1 with Propensity Score Matching (PSM) method, and finally included in infection limitation group and inflammation rest group (n = 50). Patients in both groups were treated with stage I operation.

Results

Before PSM, there were significant differences between the two groups in terms of gender, age, BMI, and the number of patients with previous infection requiring incision and drainage (p < 0.05). After PSM, there were no statistically significant differences in general information between the two groups (p > 0.05). There was no significant difference in healing, incidence of postoperative complications and recurrence rate between the two groups (p > 0.05).

Conclusion

There is no significant difference in the clinical efficacy comparison of surgical treatment for congenital preauricular fistula between the infection-localized phase and inflammation-quiescent stage I surgery with PSM.

Level of Evidence

Level 3.

目的探讨倾向匹配评分，比较局部感染与炎性静止I期手术治疗先天性耳前瘘的临床疗效。方法选择2022年1月~ 2023年8月我院收治的先天性耳前瘘患者120例。根据手术方式分为限制感染组（n = 63）和炎症休止组（n = 57）。采用倾向评分匹配法（Propensity Score Matching， PSM）将两组按1:1进行匹配，最终分为感染限制组和炎症休息组（n = 50）。两组患者均行一期手术治疗。结果PSM治疗前，两组患者在性别、年龄、BMI、既往感染需要切开引流患者数量等方面差异均有统计学意义（p < 0.05）。PSM后，两组一般信息比较，差异无统计学意义（p > 0.05）。两组患者愈合、术后并发症发生率及复发率比较，差异均无统计学意义（p > 0.05）。结论PSM治疗先天性耳前瘘感染局限期与炎症静止期手术治疗的临床疗效比较无显著差异。证据等级：3级。

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引用次数: 0

Posturography techniques to identify balance problems in elderly individuals with vestibulopathy – a comparison study 体位摄影技术识别老年前庭病变患者平衡问题的比较研究

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology

Pub Date : 2025-11-26 DOI: 10.1016/j.bjorl.2025.101743

Cibele Brugnera , Raquel Mezzalira , Lucas Resende Lucinda Mangia , Luiz Cezar da Silveira , Bruno Souza , Roseli Saraiva Moreira Bittar

Objective

To compare the postugraphic outcomes of two different methods in four basic postural conditions.

Methods

The individuals with vestibular disorders were divided into two subgroups according to their age: more than 60-years old and aged between 18 and 60. All the participants underwent to computerized dynamic posturography (EquiTest System®) and a mobile posturography (Vertiguard System®) in four test conditions: (1) Eyes open and stable surface, (2) Eyes closed and stable surface, (4) Eyes open and unstable surface, (5) Eyes closed and unstable surface.

Results

The elderly group presented worse overall outcomes in computerized dynamic posturography compared to controls. These outcomes were not different between groups when mobile posturography was used. For both methods, the results were not different between groups when the Conditions 1, 2 and 5 were evaluated separately. A significantly higher proportion of elderly subjects exhibited alterations in C4 during mobile posturography.

Conclusion

Computerized dynamic posturography was overall more sensitive at detecting abnormal postural sway in elderly individuals with vestibular disorders. In mobile posturography, Condition 4 also seemed particularly sensitive at detecting postural instability.

Level of evidence

2.

目的比较两种方法在四种基本体位条件下的体位成像效果。方法将前庭功能障碍患者按年龄分为60岁以上和18 ~ 60岁两组。所有参与者在四种测试条件下进行了计算机动态体位记录（EquiTest System®）和移动体位记录（Vertiguard System®）：(1)睁眼和稳定表面，(2)闭眼和稳定表面，(4)睁眼和不稳定表面，(5)闭眼和不稳定表面。结果与对照组相比，老年组在计算机动态体位照相中的总体结果较差。当使用移动姿势照相时，这些结果在两组之间没有差异。两种方法分别评价条件1、条件2和条件5时，两组结果均无差异。老年受试者在移动姿势时C4发生改变的比例明显更高。结论计算机动态体位术对老年前庭疾病患者异常体位摆动的检测总体上更为灵敏。在移动姿势照相中，Condition 4在检测姿势不稳定方面似乎也特别敏感。证据水平2。

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引用次数: 0