Efficacy Analysis of Endoscopic Type 1 Tympanoplasty for Chronic Suppurative Otitis Media with Otomycosis.

Linglan Gu, Yuhui Deng, Ying Zhou, Wuqing Wang, Dongdong Ren, Jianghong Xu
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Abstract

Objective: To analyze the clinical effect of tympanoplasty performed for chronic suppurative otitis media (CSOM) patients with otomycosis under the oto-endoscope. Methods: A retrospective analysis was conducted on the healing of the tympanic membrane and hearing improvement of 431 CSOM patients who underwent endoscopic type 1 tympanoplasty. The patients with CSOM were divided into the control group (n = 203, without otomycosis) and the trial group (n = 184, with otomycosis). The patients were followed up for at least 3 months. The graft uptake rate and hearing improvement were compared. Results: The graft uptake rate was 94.57% (174/184) in the trial group and 96.06% (195/203) in the control group, indicating no significant difference between the 2 groups. The preoperative and postoperative average air-conduction hearing thresholds of CSOM with otomycosis were 42.68 ± 11.46 dBHL and 33.01 ± 11.51 dBHL, respectively (P = .000). Mean air-bone gap (ABG) reduction values were 3.96 ± 7.20 dBHL and 3.34 ± 7.96 dBHL, respectively. There was no significant difference in the average ABG (P = .420) and average air-conduction hearing threshold (P = .649) between the trial group and the control group after operation. The culture results of the CSOM group with otomycosis showed that the most common fungal genus was Aspergillus (87/173), with 32 cases of mixed infection of fungi and bacteria, and the most common mixed infection of bacteria was Staphylococcus epidermidis (9/32). The failure graft uptake was noticed in 8.8% (5/57) cases in the trial group with postoperative fungal infection and 3.9% (5/127) without otomycosis (P = .289). No significant difference was found in the successful healing rate among age, duration, perforation size, fungal type, postoperative fungal infection. Conclusion: CSOM with otomycosis is not a contraindication for endoscopic type 1 tympanoplasty, and external auditory canal fungal infection does not affect postoperative healing and hearing improvement. Intraoperative repeated rinsing with povidone-iodine may reduce the occurrence of postoperative infection.

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内窥镜 1 型鼓室成形术治疗慢性化脓性中耳炎合并耳霉菌病的疗效分析。
目的分析在耳内窥镜下为患有耳霉菌病的慢性化脓性中耳炎(CSOM)患者实施鼓室成形术的临床效果。方法:对鼓室成形术的临床效果进行回顾性分析:对 431 名接受内窥镜 1 型鼓室成形术的 CSOM 患者的鼓膜愈合和听力改善情况进行回顾性分析。CSOM 患者被分为对照组(203 人,未患耳霉菌病)和试验组(184 人,患耳霉菌病)。对患者进行了至少 3 个月的随访。比较移植物吸收率和听力改善情况。结果显示试验组的移植物吸收率为 94.57%(174/184),对照组为 96.06%(195/203),两组之间无显著差异。耳霉菌病 CSOM 的术前和术后平均气导听阈分别为 42.68 ± 11.46 dBHL 和 33.01 ± 11.51 dBHL(P = .000)。平均气骨间隙(ABG)降低值分别为 3.96 ± 7.20 dBHL 和 3.34 ± 7.96 dBHL。试验组和对照组术后的平均气骨间隙(ABG)(P = .420)和平均气导听阈(P = .649)无明显差异。耳霉菌病 CSOM 组的培养结果显示,最常见的真菌属是曲霉菌(87/173),真菌和细菌混合感染 32 例,最常见的细菌混合感染是表皮葡萄球菌(9/32)。试验组中有 8.8%(5/57)的病例术后出现真菌感染,3.9%(5/127)的病例未出现耳霉菌病(P = .289),移植物吸收失败。在成功愈合率方面,年龄、病程、穿孔大小、真菌类型、术后真菌感染均无明显差异。结论CSOM合并耳霉菌病并非内窥镜下1型鼓室成形术的禁忌症,外耳道真菌感染不会影响术后愈合和听力改善。术中用聚维酮碘反复冲洗可减少术后感染的发生。
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