Comparative impact of the affordable care act on breast cancer outcomes among women in two US states.

IF 3.5 3区 医学 Q2 ONCOLOGY Frontiers in Oncology Pub Date : 2024-11-07 eCollection Date: 2024-01-01 DOI:10.3389/fonc.2024.1460714
Oluwasegun Akinyemi, Mojisola Fasokun, Terhas Weldeslase, Eunice Odusanya, Irene Akinyemi, Kailyn Geter, Meghana Akula, Miriam Michael, Kakra Hughes, Robin Williams
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Abstract

Introduction: Since the implementation of the Patient Protection and Affordable Care Act (ACA) and Medicaid expansion, states that adopted the policy have seen reduced uninsured rates. However, it is unclear whether increased healthcare access, particularly for minority and socioeconomically disadvantaged groups, has translated into measurable improvements in health outcomes.

Objective: Our study aims to evaluate the impact of the ACA and Medicaid expansion on breast cancer outcomes in Louisiana, which has implemented the policy, compared to Georgia, which has not, as of 2024.

Methodology: We conducted a retrospective study using SEER registry data from January 2011 to December 2021, including women aged 18-64 diagnosed with breast cancer. The impact of the ACA and Medicaid expansion on cancer-specific survival (CSS), overall survival (OS), and stage at presentation was evaluated. The cohort was divided into pre-ACA (2011-2015) and post-ACA (2017-2021) periods, with a one-year washout (2016). A difference-in-difference (DID) approach compared outcomes between Louisiana and Georgia.

Results: The study analyzed 62,381 women with breast cancer, with 32,220 cases in the pre-ACA period (51.7%) and 30,161 in the post-ACA period (48.3%). In Georgia, 43,279 women were included (52.3% pre-ACA vs. 47.7% post-ACA), while Louisiana had 19,102 women (50.1% pre-ACA vs. 49.9% post-ACA). Medicaid expansion in Louisiana was associated with a 0.26 percentage point reduction in overall deaths (95% CI: -10.9 to 10.4) and a 5.97 percentage point reduction in cancer-specific mortality (95% CI: -26.1 to 14.2). There was also no significant difference in disease stage at presentation compared to Georgia.

Conclusion: This study found no significant differences in overall mortality, cancer-specific mortality, or disease stage at presentation among women with breast cancer in Louisiana, which implemented Medicaid expansion in 2016, compared to Georgia, which has not expanded Medicaid.

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可负担医疗法案对美国两个州妇女乳腺癌治疗效果的影响比较。
导言:自《患者保护与平价医疗法案》(ACA)实施并扩大医疗补助范围以来,采用该政策的各州的无保险率有所下降。然而,目前还不清楚医疗服务的增加(尤其是对少数民族和社会经济弱势群体而言)是否已转化为健康状况的显著改善:我们的研究旨在评估 ACA 和医疗补助扩展对路易斯安那州乳腺癌治疗效果的影响:我们利用 2011 年 1 月至 2021 年 12 月期间的 SEER 登记数据开展了一项回顾性研究,研究对象包括 18-64 岁确诊为乳腺癌的女性。我们评估了 ACA 和医疗补助扩展对癌症特异性生存率 (CSS)、总生存率 (OS) 和发病分期的影响。队列被分为ACA前(2011-2015年)和ACA后(2017-2021年)两个时期,并有一年的冲洗期(2016年)。采用差异法(DID)比较了路易斯安那州和佐治亚州的结果:研究分析了 62,381 名患乳腺癌的妇女,其中 32,220 例发生在 ACA 前时期(51.7%),30,161 例发生在 AACA 后时期(48.3%)。佐治亚州纳入了 43 279 名妇女(《医疗补助法案》实施前为 52.3%,《医疗补助法案》实施后为 47.7%),路易斯安那州纳入了 19 102 名妇女(《医疗补助法案》实施前为 50.1%,《医疗补助法案》实施后为 49.9%)。路易斯安那州扩大医疗补助计划后,总死亡人数减少了 0.26 个百分点(95% CI:-10.9 至 10.4),癌症特异性死亡率减少了 5.97 个百分点(95% CI:-26.1 至 14.2)。与格鲁吉亚相比,发病时的疾病分期也没有明显差异:本研究发现,2016年扩大医疗补助范围的路易斯安那州与未扩大医疗补助范围的佐治亚州相比,乳腺癌女性患者的总死亡率、癌症特异性死亡率或发病阶段均无明显差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Frontiers in Oncology
Frontiers in Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
6.20
自引率
10.60%
发文量
6641
审稿时长
14 weeks
期刊介绍: Cancer Imaging and Diagnosis is dedicated to the publication of results from clinical and research studies applied to cancer diagnosis and treatment. The section aims to publish studies from the entire field of cancer imaging: results from routine use of clinical imaging in both radiology and nuclear medicine, results from clinical trials, experimental molecular imaging in humans and small animals, research on new contrast agents in CT, MRI, ultrasound, publication of new technical applications and processing algorithms to improve the standardization of quantitative imaging and image guided interventions for the diagnosis and treatment of cancer.
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